Podcast
Questions and Answers
Hyperhomocysteinemia has been positively correlated with the risk of peripheral, cerebrovascular, and coronary artery disease as well as venous thromboembolism (VTE).
Hyperhomocysteinemia has been positively correlated with the risk of peripheral, cerebrovascular, and coronary artery disease as well as venous thromboembolism (VTE).
True
Homocysteine promotes coagulation by decreasing factor V and factor XI activity.
Homocysteine promotes coagulation by decreasing factor V and factor XI activity.
False
Folic acid and vitamin B12 have been reported to increase serum homocysteine levels.
Folic acid and vitamin B12 have been reported to increase serum homocysteine levels.
False
The use of B complex vitamins to reduce cardiovascular disease in patients with PAD is recommended.
The use of B complex vitamins to reduce cardiovascular disease in patients with PAD is recommended.
Signup and view all the answers
There are data demonstrating that folic acid and vitamin B12 therapy reduces adverse cardiovascular events.
There are data demonstrating that folic acid and vitamin B12 therapy reduces adverse cardiovascular events.
Signup and view all the answers
Arteriosclerosis affects the intima of large and medium-sized arteries.
Arteriosclerosis affects the intima of large and medium-sized arteries.
Signup and view all the answers
Atherosclerosis is a diffuse process affecting the muscle fibers and the endothelial lining of the walls of small arteries and arterioles.
Atherosclerosis is a diffuse process affecting the muscle fibers and the endothelial lining of the walls of small arteries and arterioles.
Signup and view all the answers
Atherosclerosis rarely occurs without arteriosclerosis, and the terms are used interchangeably.
Atherosclerosis rarely occurs without arteriosclerosis, and the terms are used interchangeably.
Signup and view all the answers
The most common direct results of atherosclerosis in arteries include dilation of the lumen.
The most common direct results of atherosclerosis in arteries include dilation of the lumen.
Signup and view all the answers
Atherosclerosis indirectly results in malnutrition and subsequent fibrosis of the organs supplied by the sclerotic arteries.
Atherosclerosis indirectly results in malnutrition and subsequent fibrosis of the organs supplied by the sclerotic arteries.
Signup and view all the answers
HDL and low-density lipoprotein are two types of atherosclerotic lesions.
HDL and low-density lipoprotein are two types of atherosclerotic lesions.
Signup and view all the answers
Fibrous plaques are composed of smooth muscle cells, collagen fibers, plasma components, and lipids.
Fibrous plaques are composed of smooth muscle cells, collagen fibers, plasma components, and lipids.
Signup and view all the answers
Fatty streaks predispose a person to the formation of fibrous plaques and are reversible.
Fatty streaks predispose a person to the formation of fibrous plaques and are reversible.
Signup and view all the answers
Injury to the endothelium decreases the aggregation of platelets and monocytes at the site of injury.
Injury to the endothelium decreases the aggregation of platelets and monocytes at the site of injury.
Signup and view all the answers
Collateral circulation arises from preexisting vessels that enlarge to reroute blood flow around a hemodynamically significant stenosis or occlusion.
Collateral circulation arises from preexisting vessels that enlarge to reroute blood flow around a hemodynamically significant stenosis or occlusion.
Signup and view all the answers
Peripheral artery disease (PAD) is less severe in patients with diabetes compared to patients without diabetes.
Peripheral artery disease (PAD) is less severe in patients with diabetes compared to patients without diabetes.
Signup and view all the answers
Diabetes affects the onset and progression of atherosclerosis through a single factor.
Diabetes affects the onset and progression of atherosclerosis through a single factor.
Signup and view all the answers
C-reactive protein (CRP) levels are not associated with an increased risk of damage in the vasculature.
C-reactive protein (CRP) levels are not associated with an increased risk of damage in the vasculature.
Signup and view all the answers
Elevated blood glucose levels do not pose any risk to cardiovascular health.
Elevated blood glucose levels do not pose any risk to cardiovascular health.
Signup and view all the answers
HDL (high-density lipoprotein) levels are not mentioned as a risk factor for cardiovascular disease.
HDL (high-density lipoprotein) levels are not mentioned as a risk factor for cardiovascular disease.
Signup and view all the answers
Atherosclerosis can develop in any part of the vascular system.
Atherosclerosis can develop in any part of the vascular system.
Signup and view all the answers
Females are more likely to have below-the-knee pathology than males.
Females are more likely to have below-the-knee pathology than males.
Signup and view all the answers
Atherosclerosis can occur only in the proximal lower extremity, and not distal to the knee.
Atherosclerosis can occur only in the proximal lower extremity, and not distal to the knee.
Signup and view all the answers
The reaction-to-injury theory completely explains the pathogenesis of atherosclerosis.
The reaction-to-injury theory completely explains the pathogenesis of atherosclerosis.
Signup and view all the answers
Vascular endothelial cell injury can result from prolonged hemodynamic forces, chemical exposure, and chronic hyperlipidemia.
Vascular endothelial cell injury can result from prolonged hemodynamic forces, chemical exposure, and chronic hyperlipidemia.
Signup and view all the answers
