8. Contraceptives

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Questions and Answers

A 28-year-old patient who weighs 210 lbs is interested in using the transdermal contraceptive patch. What is the MOST appropriate counseling point regarding its effectiveness?

  • The patch should be applied to the upper thigh for optimal absorption.
  • She should use two patches simultaneously to ensure adequate hormone levels.
  • The patch is highly effective regardless of weight.
  • The patch may have decreased efficacy due to her weight. (correct)

A patient is prescribed a vaginal ring for contraception. Which instruction should the patient receive regarding the ring's usage?

  • Insert the ring at the start of menses, leave it in place for three weeks, and remove it for one week to allow for withdrawal bleeding. (correct)
  • Insert the ring at any point during the menstrual cycle and leave it in place continuously.
  • Replace the ring daily to ensure consistent hormone levels.
  • Insert the ring after intercourse, removing it 6-8 hours later.

A patient using a diaphragm for contraception should be counseled to:

  • Use talcum powder to ensure proper insertion and placement.
  • Insert the diaphragm no more than 1 hour prior to intercourse.
  • Leave the diaphragm in place for at least 24 hours post-intercourse, but no longer.
  • Combine the diaphragm with spermicidal jelly or cream for enhanced effectiveness. (correct)

Which of the following is a CONTRAINDICATION for the placement of a cervical cap to prevent pregnancy?

<p>Abnormal pap smear. (B)</p> Signup and view all the answers

A patient using a contraceptive sponge should be MOST concerned about which potential complication if the sponge is left in place for longer than the recommended duration?

<p>Increased risk of toxic shock syndrome (TSS) (A)</p> Signup and view all the answers

A 36-year-old patient with a history of migraines with aura is seeking contraception. Which of the following options is most appropriate?

<p>A progestin-only pill. (D)</p> Signup and view all the answers

A patient reports experiencing breakthrough bleeding while taking a low-dose combined oral contraceptive. What is the most appropriate initial course of action?

<p>Reassure the patient that this is common and usually resolves spontaneously. (A)</p> Signup and view all the answers

Which of the following is a major benefit of combined oral contraceptive pills, besides pregnancy prevention?

<p>Reduced risk of ovarian cancer. (D)</p> Signup and view all the answers

A 28-year-old lactating woman is seeking contraception. Which of the following is the most appropriate contraceptive method for her?

<p>Progestin-only pill (C)</p> Signup and view all the answers

Which of the following characteristics makes adolescents ideal candidates for IUDs, according to the American Academy of Pediatrics (AAP)?

<p>Suitability for long-acting reversible contraception (LARC) methods, reducing reliance on user compliance. (B)</p> Signup and view all the answers

A patient presents with unilateral numbness, weakness, and severe leg pain after starting combined oral contraceptives. What is the most appropriate next step?

<p>Discontinue the contraceptive and switch to a non-hormonal method. (B)</p> Signup and view all the answers

A 28-year-old patient is interested in the copper IUD (ParaGard). Which mechanism of action should you explain to her?

<p>Creation of a cytotoxic environment in the endometrium, impairing sperm motility and fertilization, and potentially inhibiting implantation. (C)</p> Signup and view all the answers

A patient using progestin-only pills calls the clinic and states she took her pill 5 hours late. What instructions should the provider give?

<p>Take the pill now, continue with the regular schedule, and use backup contraception for the next 48 hours. (C)</p> Signup and view all the answers

A patient on continuous combined oral contraceptives reports experiencing a severe headache. Which of the following is the most important next step?

<p>Assess the patient for signs and symptoms of stroke or migraine, and evaluate for other potential causes. (D)</p> Signup and view all the answers

What is the recommended administration schedule for depot medroxyprogesterone acetate (Depo-Provera) injections?

<p>Every 3 months, administered within the first 5 days of menstruation, with a safety margin of at least 14 weeks. (D)</p> Signup and view all the answers

A 30-year-old patient with a history of well-controlled hypertension and who smokes less than half a pack of cigarettes daily is seeking contraception. Which of the following is the MOST appropriate contraceptive method?

<p>Etonogestrel implant (Nexplanon). (B)</p> Signup and view all the answers

Which of the following scenarios presents an absolute contraindication to the use of combined hormonal contraceptives?

<p>A 38-year-old patient with a history of migraine with aura. (B)</p> Signup and view all the answers

Which of the following is a contraindication to the use of etonogestrel implants (Nexplanon)?

<p>Unexplained abnormal vaginal bleeding. (D)</p> Signup and view all the answers

A 25-year-old patient presents requesting emergency contraception 80 hours after unprotected intercourse. Which of the following is the MOST appropriate recommendation?

<p>Insert a copper IUD (ParaGard). (C)</p> Signup and view all the answers

A 34-year-old patient with a history of irregular menstrual cycles and suspected endometriosis is seeking contraception. She expresses concern about potential bone density loss due to hormonal methods. Which of the following contraceptive options would be MOST appropriate, considering her concerns and history?

<p>Copper IUD (ParaGard). (A)</p> Signup and view all the answers

A 26-year-old patient with a BMI of 35 requests contraception. She is concerned about weight gain, has a history of migraines with aura, and has undiagnosed vaginal bleeding. Her blood pressure is consistently around 145/95 mmHg. Which of the following contraceptive methods is MOST appropriate and safe for this patient?

<p>Copper IUD (ParaGard). (A)</p> Signup and view all the answers

What is the MOST common surgical approach employed for female sterilization?

<p>Minilaparotomy (A)</p> Signup and view all the answers

Which of the following is a potential long-term complication following a male vasectomy?

<p>Chronic testicular pain (C)</p> Signup and view all the answers

Which of the following is a component of pre-sterilization counseling that is essential for informed consent?

<p>Discussion of the permanent nature of the procedure (A)</p> Signup and view all the answers

After how long of regular, unprotected intercourse should a couple, where the woman is over 35 years old, be evaluated for infertility?

<p>6 months (B)</p> Signup and view all the answers

Which anatomical or physiological factor is NOT typically required for successful conception?

<p>Absence of cervical mucus (D)</p> Signup and view all the answers

Which of the following is the MOST common cause of female infertility?

<p>Ovulatory dysfunction (B)</p> Signup and view all the answers

Azoospermia is not obtained until how many weeks post vasectomy?

<p>10 weeks (D)</p> Signup and view all the answers

Which of the following is a common method of assisted reproductive technology (ART)?

<p>In vitro fertilization (IVF) (B)</p> Signup and view all the answers

A couple is undergoing intrauterine insemination (IUI), and the woman is prescribed clomiphene citrate. What is the PRIMARY purpose of this medication in this context?

<p>To induce and stimulate ovulation (D)</p> Signup and view all the answers

What ethical consideration should be discussed with couples undergoing infertility treatment, particularly IVF?

<p>The ethical issues surrounding multifetal pregnancy reduction (D)</p> Signup and view all the answers

Which of the following is the MOST likely mechanism of action of combination oral contraceptive pills?

<p>Preventing ovulation and thickening cervical mucus. (D)</p> Signup and view all the answers

A 25-year-old woman who is breastfeeding her 2-month-old infant is seeking contraception. Considering the information provided, which of the following would be the MOST appropriate recommendation?

<p>A progestin-only pill. (D)</p> Signup and view all the answers

A 42-year-old patient with a history of well-controlled hypertension and no other significant medical issues is seeking contraception. Which of the following methods would be least appropriate for her?

<p>Combined oral contraceptive pill. (B)</p> Signup and view all the answers

Which of the following is a potential advantage of continuous combined oral contraceptive regimens compared to the classic 21-day active hormone/7-day placebo regimen?

<p>Shorter or less frequent menstrual periods. (D)</p> Signup and view all the answers

A patient taking combination oral contraceptives reports experiencing new-onset headaches. Which of the following headache characteristics would warrant immediate evaluation and discontinuation of the OCP?

<p>Severe headache accompanied by slurred speech. (A)</p> Signup and view all the answers

A patient presents with a chief complaint of new onset amenorrhea while taking OCPs. What is the MOST appropriate course of action?

<p>Obtain a pregnancy test. (C)</p> Signup and view all the answers

A patient presents to the clinic complaining of right upper quadrant (RUQ) pain. She is sexually active and currently takes OCPs. What is the MOST appropriate course of action?

<p>Evaluate for cholecystitis or cholelithiasis. (B)</p> Signup and view all the answers

A patient is interested in starting birth control. She is currently 36 years old and smokes occasionally. What is the MOST appropriate birth control for this patient?

<p>Nonhormonal birth control. (B)</p> Signup and view all the answers

Which of the following is the MOST likely side effect of Progestin only pills?

<p>Increases breakthrough bleeding (C)</p> Signup and view all the answers

Nextstellis is a new oral contraceptive pill that combines estetrol with drospirenone. Which of the following is the MOST accurate description of estetrol?

<p>A novel estrogen. (D)</p> Signup and view all the answers

A new oral contraceptive (OC) containing estetrol is being marketed as having less impact on coagulation markers compared to traditional OCs. What is the primary distinguishing characteristic of estetrol in this new formulation?

<p>It is a naturally occurring estrogen derived from a plant source. (C)</p> Signup and view all the answers

When counseling a patient on the use of the transdermal contraceptive patch, which of the following application sites is MOST appropriate to recommend?

<p>The buttocks, upper outer arm, or lower abdomen. (A)</p> Signup and view all the answers

Compared to daily oral contraceptive pills, how is the hormone release pattern of a vaginal contraceptive ring designed to function?

<p>To release a consistent, low dose of hormones daily over a three-week period. (A)</p> Signup and view all the answers

Barrier contraceptives, such as condoms and diaphragms, offer benefits beyond pregnancy prevention. Which of the following sexually transmitted infections (STIs) are barrier methods known to provide some protection against?

<p>Gonorrhea, herpes, chlamydia, HIV, and HPV. (B)</p> Signup and view all the answers

A patient was initially fitted for a diaphragm three years ago and has been using it successfully. Which of the following scenarios would MOST necessitate refitting for her diaphragm?

<p>She has undergone a vaginal birth. (B)</p> Signup and view all the answers

Compared to the diaphragm, the cervical cap has a potentially higher incidence of which of the following complications?

<p>Toxic Shock Syndrome (TSS) and cervicitis. (D)</p> Signup and view all the answers

The contraceptive sponge demonstrates varying levels of effectiveness depending on a woman's parity. In which population is the contraceptive sponge generally considered more effective?

<p>Nulliparous women who have not given birth. (D)</p> Signup and view all the answers

Which of the following uterine conditions is considered an acquired contraindication to the placement of an intrauterine device (IUD)?

<p>Uterine fibroids causing distortion of the cavity. (B)</p> Signup and view all the answers

The FDA has issued a warning regarding the use of depot medroxyprogesterone acetate (DMPA) injections and bone mineral density (BMD). How does the American College of Obstetricians and Gynecologists (ACOG) currently recommend managing this concern in clinical practice?

<p>ACOG suggests that the effects of DMPA on BMD are intermediate and reversible, and does not recommend routinely limiting use to 2 years. (B)</p> Signup and view all the answers

A patient weighing 180 lbs (82 kg) requests emergency contraception approximately 48 hours after unprotected intercourse. Considering weight-related efficacy, which of the following options is likely to be MOST effective for this patient?

<p>EllaOne (ulipristal acetate 30mg) prescription. (C)</p> Signup and view all the answers

A patient started using the transdermal contraceptive patch. When should she replace the patch?

<p>Every week for three weeks, followed by a patch-free week for withdrawal bleeding. (C)</p> Signup and view all the answers

When is the vaginal ring placed for contraception?

<p>At the start of menses and left in place for three weeks. (D)</p> Signup and view all the answers

Which of the following statements about barrier contraceptives is correct?

<p>They provide some protection against the transmission of STIs. (A)</p> Signup and view all the answers

A patient asks how long a diaphragm should be left in place after intercourse. What is the correct duration?

<p>At least 6-8 hours, but not more than 24 hours. (C)</p> Signup and view all the answers

Compared to diaphragms, cervical caps have a higher association with which of the following adverse effects?

<p>Toxic Shock Syndrome (TSS) and Cervicitis. (D)</p> Signup and view all the answers

A nulliparous (never given birth) woman asks about the effectiveness of the contraceptive sponge. What is the MOST accurate counseling point?

<p>The sponge is more effective in women who have never given birth. (B)</p> Signup and view all the answers

What is a significant advantage of long-acting reversible contraceptives (LARCs) like IUDs and implants?

<p>They are 99% effective and good options for those with contraindications to estrogen. (C)</p> Signup and view all the answers

Why are adolescents considered ideal candidates for IUDs?

<p>Adolescents are more compliant with IUDs than with daily oral contraceptives. (A)</p> Signup and view all the answers

The FDA issued a warning regarding the use of depot medroxyprogesterone acetate (DMPA) injections. What was the primary concern?

<p>Concern over bone mineral density (BMD) loss. (D)</p> Signup and view all the answers

A 27 year old female presents for emergency contraception after unprotected intercourse 4 days (96 hours) prior. Which is her best option?

<p>Copper IUD (B)</p> Signup and view all the answers

Which of the following BEST describes the primary mechanism by which progestin-only pills prevent pregnancy?

<p>Thickening cervical mucus to inhibit sperm penetration. (C)</p> Signup and view all the answers

A 45-year-old patient is seeking contraception but has a history of migraines without aura. Which of the following hormonal contraceptive options would be the SAFEST to initiate?

<p>Progestin-only pill (mini-pill). (A)</p> Signup and view all the answers

What is the MOST significant advantage of continuous combined oral contraceptive regimens compared to traditional cyclic regimens?

<p>Fewer or less frequent menstrual periods. (A)</p> Signup and view all the answers

A patient using combined oral contraceptives reports experiencing new, persistent headaches. Which characteristic of the headache would necessitate IMMEDIATE discontinuation of the OCPs and further evaluation?

<p>Severe, unilateral headache preceded by visual disturbances. (C)</p> Signup and view all the answers

A patient on combined oral contraceptives presents with new-onset right upper quadrant (RUQ) pain. What is the MOST appropriate initial step in management?

<p>Order liver function tests and abdominal imaging to evaluate for hepatic issues. (B)</p> Signup and view all the answers

A 19-year-old patient who is sexually active asks about the effectiveness of different contraceptive methods. What is the BEST response?

<p>&quot;Combined hormone pills are the most effective reversible pregnancy prevention available.&quot; (B)</p> Signup and view all the answers

A patient taking a combination birth control pill reports experiencing a new breast mass. What is the most appropriate next step.

<p>Schedule an immediate evaluation to rule out possible breast cancer. (C)</p> Signup and view all the answers

A woman > 35 years of age presents and is a smoker. Which of the following hormonal contraception has a contraindication to initiation in this patient population?

<p>Combined Oral Contraceptive Pill. (D)</p> Signup and view all the answers

A patient reports to the clinic that they have been experiencing loss of vision and diplopia while taking oral contraceptive pills. What is MOST likely occurring?

<p>The patient is experiencing retinal artery thrombosis. (B)</p> Signup and view all the answers

How does the hormone release pattern of a transdermal contraceptive patch compare to daily oral contraceptive pills?

<p>Sustained Hormone Release. (A)</p> Signup and view all the answers

Following a male vasectomy, how long is typically required before complete azoospermia is achieved, necessitating a follow-up semen analysis to confirm sterility?

<p>10 weeks (B)</p> Signup and view all the answers

Which of the following is the MOST reversible female sterilization method?

<p>Hulka clip (B)</p> Signup and view all the answers

A 29-year-old female is undergoing a hysteroscopic sterilization procedure. Which of the following materials are utilized in the Essure system?

<p>Stainless steel and nickel titanium (C)</p> Signup and view all the answers

During pre-sterilization counseling, which of the following is the MOST important to emphasize to a patient?

<p>The permanent nature of the procedure. (A)</p> Signup and view all the answers

A 37-year-old woman and her partner have been trying to conceive for 7 months with regular, unprotected intercourse. What is the MOST appropriate next step in their care?

<p>Initiate infertility evaluation, including semen analysis and ovulation assessment. (C)</p> Signup and view all the answers

Which factor is LEAST critical for successful natural conception?

<p>Specific coital positioning to enhance sperm motility. (A)</p> Signup and view all the answers

A 32-year-old woman is diagnosed with infertility. What percentage of infertility cases are attributed to female factors?

<p>65% (B)</p> Signup and view all the answers

A couple is undergoing infertility treatment. The male partner's semen analysis reveals oligozoospermia. What does this finding indicate?

<p>Low sperm count in the ejaculate. (C)</p> Signup and view all the answers

During IUI, washed semen is introduced via catheter into which location?

<p>Uterus (B)</p> Signup and view all the answers

A couple is exploring IVF as an infertility treatment option. What is a critical ethical consideration that should be discussed with the couple?

<p>The ethical issues surrounding multifetal pregnancy reduction. (D)</p> Signup and view all the answers

A patient presents requesting a non-prescription oral contraceptive. Considering the information provided, what would it contain?

<p>Estetrol (D)</p> Signup and view all the answers

Following unprotected intercourse 60 hours prior, a 200 lb patient requests emergency contraception. Which agent would be MOST appropriate?

<p>Copper IUD (B)</p> Signup and view all the answers

A patient reports that their condom broke during intercourse. They seek medical care 96 hours after the incident. What contraceptive intervention is still indicated?

<p>Ulipristal acetate (A)</p> Signup and view all the answers

A patient presents requesting a diaphragm for contraception. Beyond pregnancy prevention, what additional protection does this barrier method provide?

<p>Sexually Transmitted Infections (A)</p> Signup and view all the answers

A 30-year-old patient with a history of heavy menstrual bleeding desires long-acting reversible contraception but has a known uterine fibroid distorting the cavity. Which LARC is LEAST appropriate?

<p>Copper IUD (A)</p> Signup and view all the answers

A 32-year-old nulliparous patient with a history of well-managed essential hypertension, currently controlled with lifestyle modifications alone, seeks initiation of combined oral contraceptives (COCs). Upon further questioning, she reports experiencing episodic migraines without aura, occurring approximately twice monthly and effectively managed with over-the-counter analgesics. Considering her clinical profile and the nuanced contraindications to COC use, which of the following physiological mechanisms poses the MOST significant theoretical risk necessitating judicious evaluation prior to COC initiation?

<p>Endothelial dysfunction potentiated by ethinyl estradiol, synergistically augmenting migraine frequency and severity. (C)</p> Signup and view all the answers

A 24-year-old woman, postpartum at 6 weeks and exclusively breastfeeding, presents for contraceptive counseling. She is adamant about avoiding any hormonal contraception that could potentially impact lactation. Considering the subtle pharmacodynamics of progestin-only pills (POPs) and their minimal systemic exposure compared to other hormonal methods, which of the following statements MOST accurately reflects the contemporary consensus regarding POPs and breastfeeding, informing optimal clinical decision-making?

<p>POPs are generally considered safe for use in breastfeeding women and are classified as a category 1 or 2 by WHO, with minimal impact on milk supply or infant well-being. (C)</p> Signup and view all the answers

In the context of combination oral contraceptive (COC) pharmacology, the inclusion of ethinyl estradiol serves a multifaceted role beyond endometrial stabilization and cycle regulation. Considering the intricate interplay between estrogen and progesterone components, which of the following mechanisms BEST elucidates the synergistic contribution of ethinyl estradiol to the overall contraceptive efficacy of COCs, particularly in scenarios of potential progestin breakthrough ovulation?

<p>Exerts a direct negative feedback effect on follicle-stimulating hormone (FSH) release from the anterior pituitary, effectively inhibiting follicular development and preventing dominant follicle selection. (A)</p> Signup and view all the answers

A 39-year-old patient with a history of migraines with aura and well-controlled hyperlipidemia, managed with a statin, is seeking contraception. She is a non-smoker and has no personal or family history of thromboembolic events. Given the absolute contraindications to estrogen-containing contraceptives and the nuances of migraine subtypes, which of the following progestin-based contraceptive modalities would be considered the MOST judicious initial approach, mitigating potential cerebrovascular risk while providing effective contraception?

<p>Levonorgestrel-releasing intrauterine system (LNG-IUS), offering highly localized progestin delivery with minimal systemic absorption and prolonged duration of action. (A)</p> Signup and view all the answers

A 21-year-old patient using combination oral contraceptives presents to the emergency department with acute onset of severe, unilateral leg pain, edema, and palpable cord-like tenderness in the posterior calf. She denies any recent trauma or prolonged immobilization. Considering the temporal association with COC initiation and the concerning symptomatology, which of the following represents the MOST critical and immediate next step in diagnostic and therapeutic management?

<p>Urgent duplex ultrasonography of the lower extremity to evaluate for deep vein thrombosis (DVT) and guide subsequent anticoagulant therapy. (C)</p> Signup and view all the answers

A patient using progestin-only pills (POPs) for contraception reports consistently taking her pill approximately 4 hours late each day due to her work schedule. To optimize contraceptive efficacy and mitigate the risk of unintended pregnancy, which of the following counseling points is MOST crucial regarding POP administration and the need for adjunctive contraceptive measures?

<p>Instruct the patient to use barrier contraception, such as condoms, for the subsequent 7 days whenever intercourse occurs, considering the inconsistent POP timing. (B)</p> Signup and view all the answers

Nextstellis, a novel oral contraceptive containing estetrol (E4) and drospirenone, is marketed with claims of a potentially improved safety profile compared to traditional ethinyl estradiol (EE)-based COCs, particularly regarding coagulation parameters. Which of the following pharmacological properties of estetrol BEST differentiates it from ethinyl estradiol and underpins the purported coagulation safety advantage?

<p>Estetrol demonstrates a markedly shorter half-life and reduced receptor occupancy in hepatic tissues compared to EE, potentially minimizing impact on coagulation factor production. (C)</p> Signup and view all the answers

A 27-year-old patient presents requesting initiation of a transdermal contraceptive patch. She weighs 240 lbs (109 kg) and expresses concern about contraceptive effectiveness in the context of her weight. Considering the pharmacokinetic limitations associated with transdermal hormone delivery in higher BMI individuals, which of the following counseling points MOST accurately reflects the evidence-based recommendations regarding patch efficacy and weight?

<p>Transdermal patch efficacy is significantly reduced in women weighing &gt; 90 kg (198 lbs), and alternative contraceptive methods should be strongly considered. (B)</p> Signup and view all the answers

A 41-year-old patient is considering discontinuing her long-term use of depot medroxyprogesterone acetate (DMPA) injections due to concerns about potential bone mineral density (BMD) loss, despite its contraceptive convenience. She is otherwise healthy and has no other risk factors for osteoporosis. Which of the following strategies represents the MOST evidence-based and clinically recommended approach to mitigate BMD concerns in the context of continued DMPA use, according to current ACOG guidelines?

<p>Counseling regarding weight-bearing exercise, smoking cessation, and adequate calcium intake, without routine BMD monitoring or pharmacological intervention, unless clinically indicated. (C)</p> Signup and view all the answers

In the evaluation of a couple presenting with primary infertility, the initial assessment of the male partner's semen analysis reveals normozoospermia, but with 45% of spermatozoa exhibiting hyperactivation upon capacitation assays. Considering the complex cascade of events leading to fertilization, which of the following interpretations MOST accurately reflects the potential implications of this finding for the couple's fertility prognosis?

<p>Elevated hyperactivation rates may paradoxically impair fertility by reducing directional motility and premature acrosome reaction, hindering successful oocyte penetration. (A)</p> Signup and view all the answers

What coil materials comprise Essure?

<p>Nickel, titanium (A)</p> Signup and view all the answers

Minilaparotomy facilitates occlusion of fallopian tubes via?

<p>Cautery (B)</p> Signup and view all the answers

Complete azoospermia post-vasectomy typically requires?

<p>10 weeks (C)</p> Signup and view all the answers

First line infertility treatment includes?

<p>Clomiphene citrate (A)</p> Signup and view all the answers

Female infertility accounts for what percent of infertility cases?

<p>65% (B)</p> Signup and view all the answers

Estetrol's impact on coagulation is _____ ethinyl estradiol.

<p>less than (A)</p> Signup and view all the answers

Combined pills are contraindicated in smokers over _____ years.

<p>35 (B)</p> Signup and view all the answers

Progestin thickens cervical mucus impeding _____ migration.

<p>sperm (B)</p> Signup and view all the answers

A patient on Progestin-Only Pills must take it at the same time EVERY day, and if they are more than ____ hours late, they must use back up contraception.

<p>3 (C)</p> Signup and view all the answers

Combination pills prevent _____, if that occurs the progestin will thicken cervical mucus.

<p>ovulation (C)</p> Signup and view all the answers

Besides pregnancy prevention, combination pills LOWER endometrial cancer risk by _____%

<p>50 (B)</p> Signup and view all the answers

After starting hormonal birth control, diplopia may indicate retinal _____ thrombosis.

<p>artery (C)</p> Signup and view all the answers

A patient who is lactating would benefit MOST from _____ pills.

<p>progestin-only (A)</p> Signup and view all the answers

The most effective, reversible pregnancy prevention available are _____.

<p>OCPs (B)</p> Signup and view all the answers

The hormone, _____, increases the efficacy of progesterone & stabilizes the endometrium.

<p>estrogen (C)</p> Signup and view all the answers

Compared to ethinyl estradiol, what is a primary distinguishing feature of estetrol in newer oral contraceptives?

<p>Natural origin (E)</p> Signup and view all the answers

A transdermal contraceptive patch demonstrates decreased efficacy in patients exceeding _____ lbs.

<p>198 (A)</p> Signup and view all the answers

Regarding vaginal contraceptive rings, at which point in the menstrual cycle should placement occur?

<p>Start of menses (C)</p> Signup and view all the answers

Besides pregnancy prevention, what STI does a condom NOT provide some protection against?

<p>Syphilis (B)</p> Signup and view all the answers

Post-coital, how long must a diaphragm remain inside a patient?

<p>6-8 hours (B)</p> Signup and view all the answers

Compared to diaphragms, cervical caps pose an increased incidence of _________.

<p>TSS (D)</p> Signup and view all the answers

Contraceptive sponges are MOST effective in which population?

<p>Nulliparous women (D)</p> Signup and view all the answers

Within what timeframe must Plan B be administered to be most effective?

<p>72 hours (B)</p> Signup and view all the answers

What is the MOST effective method of emergency contraception?

<p>Copper IUD (C)</p> Signup and view all the answers

If a condom breaks, advise patients to seek medical care within how many hours?

<p>120 hours (B)</p> Signup and view all the answers

Following a vasectomy, complete azoospermia, indicating sterility, is typically achieved after approximately how many weeks?

<p>Ten (D)</p> Signup and view all the answers

Among the female sterilization methods listed, which is explicitly identified as the most reversible in the provided text?

<p>Hulka clip (E)</p> Signup and view all the answers

The Essure hysteroscopic sterilization system employs a coil inserted into each fallopian tube. This coil is comprised of which combination of materials?

<p>Steel and nickel-titanium (E)</p> Signup and view all the answers

In pre-sterilization counseling, particularly for female patients, which element should be most strongly emphasized to ensure truly informed consent and minimize potential regret?

<p>Permanent nature (A)</p> Signup and view all the answers

According to the guidelines provided, a woman over the age of 35 should be evaluated for infertility after how many months of consistent, unprotected intercourse without conception?

<p>Six (A)</p> Signup and view all the answers

Within the context of natural conception, as outlined, which factor is LEAST directly related to the initial stages of fertilization and embryo formation itself?

<p>Uterine transport (D)</p> Signup and view all the answers

Female factors are implicated in a significant proportion of infertility cases. According to the provided data, approximately what percentage of infertility cases are attributed to female-related causes?

<p>Sixty-five (C)</p> Signup and view all the answers

Oligozoospermia, a term frequently used in male infertility evaluations, specifically refers to a deficiency in which semen parameter?

<p>Sperm count (C)</p> Signup and view all the answers

In the intrauterine insemination (IUI) procedure, washed semen is introduced directly into which anatomical location within the female reproductive system?

<p>Uterus (C)</p> Signup and view all the answers

When counseling couples undergoing infertility treatment, particularly in vitro fertilization (IVF), which ethical consideration regarding potential pregnancy outcomes is most critical to address?

<p>Multifetal reduction (D)</p> Signup and view all the answers

A patient using combination oral contraceptives reports new onset of unilateral visual disturbances. Which of the following is the MOST concerning potential etiology?

<p>Retinal artery thrombosis (B)</p> Signup and view all the answers

Compared to traditional cyclic combined oral contraceptive regimens, continuous regimens are designed to MOST significantly reduce the frequency of:

<p>Withdrawal bleeding (B)</p> Signup and view all the answers

A patient consistently takes her progestin-only pill (POP) four hours later than her scheduled time. To maintain optimal efficacy, she should be advised to use backup contraception for the next:

<p>48 hours (E)</p> Signup and view all the answers

In female sterilization via minilaparotomy, fallopian tube occlusion is MOST commonly achieved through which method?

<p>Filshie clips (C)</p> Signup and view all the answers

Which of the following BEST describes the primary mechanism by which estetrol, a novel estrogen in Nextstellis, is suggested to have a potentially improved coagulation profile compared to ethinyl estradiol?

<p>Reduced hepatic impact on coagulation factors (D)</p> Signup and view all the answers

For a couple with unexplained infertility, the INITIAL first-line treatment approach, prior to considering advanced reproductive technologies, typically includes:

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A 38-year-old woman, gravida 0, is interested in a diaphragm for contraception. Which of the following instructions regarding diaphragm refitting is MOST accurate and clinically relevant?

<p>Refitting is recommended after each pregnancy. (D)</p> Signup and view all the answers

Following a successful vasectomy, complete azoospermia, confirming sterility, is typically achieved after approximately how many weeks?

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The Essure system for hysteroscopic sterilization utilizes micro-inserts primarily composed of which materials?

<p>Titanium and polyethylene terephthalate (PET) fibers (B)</p> Signup and view all the answers

In the context of infertility evaluation, a semen analysis result indicating 'oligozoospermia' MOST accurately denotes:

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Flashcards

Contraceptive Patch

A contraceptive skin patch that releases hormones for one week, replaced weekly for three weeks, followed by a patch-free week.

Vaginal Ring

Estrogen and progestin releasing ring placed vaginally for 3 weeks then removed for 1 week to allow for withdrawal bleeding. Releases hormones daily.

Diaphragm Contraceptive

A dome-shaped latex device used with spermicide that fits over the cervix, inserted up to 6 hours before intercourse and left in place for 6-8 hours after, not exceeding 24 hours total.

Cervical Cap

A barrier method that covers only the cervix, needs to stay in place for 6 hours post sex. Higher risk of TSS.

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Contraceptive Sponge

A spermicide-containing sponge placed over the cervix, effective for 24 hours, and more effective in women who have not given birth.

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Most effective contraception?

Most effective pregnancy prevention method, includes pills, injectable preparations, implantable rods, IU systems, patches and rings.

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Hormonal contraceptive serious SE

Loss of vision, diplopia; unilateral numbness/weakness; severe chest/neck pain; severe leg pain/tenderness; hemoptysis, acute SOB; hepatic mass/tenderness.

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Hormonal contraceptive concerning SE

Amenorrhea, breast mass, RUQ pain, severe headache, galactorrhea.

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Combo Pill MOA

Estrogen & Progesterone: Prevents ovulation, thickens cervical mucus, creates atrophic endometrium.

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Combo pill CIs

Women >35 who smoke; Hx of thromboembolism, CAD, CHF, CVA; Hx of migraine w/ aura.

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Combo pill benefits

Shorter, less painful periods; lower incidence of endometrial & ovarian Ca, benign breast/ovarian diseases, pelvic infection, ectopic pregnancies.

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Progestin-only pill MOA

Thickens cervical mucus, must be taken at the same time every day.

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Progestin-only pill indications

Lactating women; women >40 yrs; when estrogen is contraindicated.

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Hormonal IUD/Implant Advantages

Very effective (99%) but higher up-front costs. Rapid return to fertility.

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IUD Ideal Candidate

Adolescents are ideal candidates per AAP. Check placement in weeks after insertion.

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IUD Contraindications

Congenital/acquired anatomical distortions of uterus, current AUB, active pelvic infection, pregnancy.

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IUD Risks

Increased incidence of PID, spontaneous expulsion, uterine perforation, embedded in uterine wall (10-16%).

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Hormonal IUD Action/SE

Thickens cervical mucus; place w/n 7 days of LMP or during menses. Side effects: irregular bleeding/spotting, amenorrhea, increased risk of ovarian cysts

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Copper IUD (ParaGard)

Interferes w/ sperm motility & fertilization; may inhibit implantation. Creates cytotoxic response in endometrium.

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Depot Medroxyprogesterone Use

Injectable progesterone every 3 months w/in 1st 5 days of menses (last at least 14 weeks: “safety margin”).

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Implant Contraindications

Pts with hormone responsive conditions (breast ca), unevaluated vaginal bleeding, breast malignancy, H/O thromboembolism or cerebrovascular disease, liver dysfunction

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Contraception

Methods to prevent pregnancy; effectiveness varies based on correct and consistent use.

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Hormonal Contraception

Hormone-based methods like pills, patches, rings, injections, and implants.

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Barrier Contraceptives

Physical barriers like condoms, diaphragms, and cervical caps.

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Intrauterine Devices (IUDs)

Devices inserted into the uterus to prevent pregnancy.

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Natural Family Planning

Tracking menstrual cycles and avoiding intercourse during fertile periods.

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Emergency Contraception

Methods used after unprotected intercourse to prevent pregnancy.

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Sterilization

Permanent methods of birth control for men and women.

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Infertility

The inability to conceive after one year of unprotected intercourse.

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Combination Pills

Most contain a combination of estrogen and progestin; prevent ovulation

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Nextstellis

A birth control pill that combines estetrol with drospirenone.

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Ethinyl Estradiol

Synthetic estrogen used in many oral contraceptives, now with a naturally occurring alternative.

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Estetrol

Approved by the FDA in 2021, produced from a plant source.

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Transdermal Patch

A combination method lasting one week, replaced 3x, followed by a patch-free week for withdrawal bleeding.

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Contraceptive Ring

Releases hormones daily; placed in the vagina at the start of menses and left for three weeks, then removed resulting in withdrawal bleeding.

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Condoms

Sheaths worn over the penis or inside the vagina to prevent sperm from entering.

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Long-Acting Reversible Contraceptives (LARCs)

Offer highly effective, reversible contraception via IUDs and implants.

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LARC Benefits

Good for patients with contraindications to estrogen, like smokers over the age of 35, and those desiring a rapid return to fertility.

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Depo-Provera

Injectable progestin given every 3 months. FDA advises limiting use to 2 years due to bone mineral density concerns.

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Fertility Awareness

Avoiding intercourse during ovulation or using barrier methods during ovulation. Includes the calendar, BBT, and cervical mucus methods.

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Vasectomy & Azoospermia

Azoospermia (absence of sperm) is typically achieved about 10 weeks after the vasectomy procedure.

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Vasectomy Complications

Common complications include: bleeding, hematoma, acute & chronic pain, local skin infection, depression & altered body image.

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Female Sterilization Methods

Electrocautery, Hulka clip (most reversible), Falope ring, and Filshie clip.

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Minilaparotomy

Minilaparotomy is the most common surgical approach for female sterilization

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Essure System

A stainless steel & nickel titanium coil is inserted into each fallopian tube.

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Sterilization Counseling

Permanent nature, alternative options, reasons for sterilization, risk screening, procedure risks/benefits, failure possibility, STD protection.

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Infertility Definition

Inability to conceive after 12 months of frequent, unprotected intercourse (or 6 months if the woman is >35 years old).

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Conception Requirements

Ovulation, sperm, patent tract/fertilization, viable embryo, transport to uterus, implantation.

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Infertility Causes

Female factors (65%), male factors (20%), unexplained/other (15%).

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Assisted Reproductive Technology (ART)

Artificial insemination (IUI) and in vitro fertilization (IVF).

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OCPs

The most effective reversible pregnancy prevention available, including pills, injectables, IUDs, patches & rings.

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Progestin Compounds

Synthetic progestins, including norgesterel, norethindrone, desogestrel, norgestimate and drespirenone

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Estrogen Compounds

Synthetic estrogens found in oral contraceptives, including ethinyl estradiol and estradiol valerate

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Continuous Regimens

Shorter or less frequent menstrual periods achieved through extended regimens.

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When to D/C Combination Pills

Increases in BP, worsening migraines

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Progestin-Only Pills

Thickens cervical mucus, take at the same time EVERY day, starting on 1st day of menses.

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Hormonal Contraceptives - Serious SE

Loss of vision, diplopia; unilateral numbness/weakness; severe chest/neck pain; hemoptysis, acute SOB; hepatic mass/tenderness.

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Hormonal Contraceptives - Concerning SE

Amenorrhea, breast mass, RUQ pain, severe headache, galactorrhea.

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Contraceptive Patch Schedule

Replaced weekly for 3 weeks, followed by a week without a patch to allow for withdrawal bleeding.

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Contraceptive Ring Use

Inserted into the vagina at the start of menses and left in place for 3 weeks, followed by removal to allow for withdrawal bleeding.

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Barrier Contraceptive Limitations

Offer some STI protection but have higher failure rates due to user error or damage.

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Latex Condom Benefit

Provide protection against HIV and other STIs.

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Diaphragm Side Effects & Fitting

Higher rate of UTIs and requires fitting from a healthcare practitioner.

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Hormonal IUD Side Effects

Irregular bleeding/spotting, amenorrhea, or increased risk of ovarian cysts.

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Emergency Contraception MOA

Work by preventing ovulation or fertilization; they do not affect implantation.

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Azoospermia Post-Vasectomy

Complete absence of sperm in ejaculate, usually achieved about 10 weeks post-vasectomy.

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Vasectomy

Surgical contraception for men. Severing the vas deferens.

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Female Sterilization

Surgical contraception in females involving occlusion of fallopian tubes

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Fallopian Tube Occlusion Methods

Clips, rings, cautery

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Hysteroscopic Sterilization

Outpatient procedure to access fallopian tubes via the cervix

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Requirements for Conception

Ovulation, sperm, patent tract/fertilization, viable embryo, transport to uterus, implantation.

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Diaphragm

Barrier method, dome-shaped, placed over cervix with spermicide; requires fitting.

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Contraceptive Implant

Hormone-releasing (progestin) inserted under the skin of the upper arm, effective for up to 3 years.

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Emergency Contraception (ECP)

Inhibit ovulation following unprotected sex; most effective when taken within 72 hours.

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Estrogen in Combination Pills

Estrogen increases efficacy of progesterone & stabilizes the endometrium.

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Progestin-Only Pill Instructions

Must be taken at the same time EVERY day, starting on 1st day of menses.

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Condom Types

Sheaths worn over the penis or inside the vagina; protect against HIV (latex only).

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Diaphragm Use

Inserted 6 hrs before intercourse; left in place for 6-8 hrs after, but no more than 24 hrs; requires fitting.

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LARCs

Highly effective and reversible, includes IUDs and hormone-eluting subdermal implants.

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Contraception Defined

Methods to prevent pregnancy. Effectiveness depends on correct and consistent use.

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OCPs Effectiveness

Pills, injectables, IUDs, patches and rings; most effective reversible method.

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Combined Hormonal Contraceptives

Estrogen + progestin that prevent ovulation, thicken cervical mucus, and create an atrophic endometrium

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Combination Pill CIs

Women >35 who smoke; Hx of thromboembolism, CAD, CHF, CVA; Hx of migraine w/ aura

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Combination Pill Benefits

Shorter, less painful periods; lower incidence of endometrial & ovarian ca; benign breast/ovarian disease, pelvic infection, ectopic pregnancies

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Hormonal Contraceptives - Critical SEs

Loss of vision, diplopia; unilateral numbness/weakness; severe chest/neck pain; hemoptysis, acute SOB; hepatic mass/tenderness

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Hormonal Contraceptives - Concerning Side Effects

Amenorrhea, breast mass, RUQ pain, severe headache, or galactorrhea.

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Nextstellis Pill

Combines estetrol (new estrogen) with drospirenone.

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Azoospermia After Vasectomy

Absence of sperm in ejaculate; typically achieved 10 weeks post-vasectomy.

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Minilaparotomy in Sterilization

Occlusion of fallopian tubes via clips, rings, or cautery.

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Essure Sterilization System

Stainless steel and nickel titanium coil inserted into each fallopian tube

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Sterilization Counseling Components

Permanent nature of the procedure, alternative methods available, reasons for choosing sterilization, screening for regret, details of procedure, possibility of failure, STD protection.

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Infertility Defined

Inability to conceive after 12 months of frequent, unprotected intercourse (or 6 months if woman is >35).

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Main Components of Infertility

Female factors (65%), male factors (20%), unexplained/other (15%).

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Study Notes

Contraception Stats

  • 45% of pregnancies in the U.S. are unintended.
  • Most unintended pregnancies occur in women didn't use contraception or used it incorrectly.
  • Birth control pills, OCPs, OCs, or BC pills are the most effective method of pregnancy prevention.
  • Injectable preparations and implantable hormonal rod are methods of hormonal birth control.
  • Hormonal contraceptives methods include injectable preparations, implantable rods, IU systems, patches, and rings.
  • Not diaphragms
  • Choice of contraceptive involves many factors, like lifestyle, career choices, and who is responsible
  • It is critical to discuss the high-risk behaviors, safer sex, and the need for condoms for additional protection from STIs.
  • Contraceptive methods do not provide protection from STIs.
  • It is paramount to always considers the overall risk-to-benefit ratio on an individual basis when choosing contraception

Contraceptive Components

  • Ethinyl estradiol and Estradiol valerate are estrogen compounds
  • Norgesterel, Ethynodiol diacetate, Norethynodrel, Norethindrone, Desogestrel, Norgestimate, and Drisporenone are progestin compounds.

Combination pills (OCPs)

  • Hormonal contraceptive side effects necessitate discontinuing the method and starting a nonhormonal one.
    • Examples include vision loss, diplopia, unilateral numbness/weakness, severe chest/neck pain, severe leg pain/tenderness, hemoptysis, acute SOB, hepatic mass, tenderness.
  • Discontinue combined hormone therapy if an Increase in the patients Blood Pressure as well as Worsening migraines are seen
  • It is imperative to seek Immediate Evaluation for these symptoms
    • Loss of vision/diplopia - possible retinal artery thrombosis Unilateral numbness, weakness, slurred speech - possible stroke Severe chest/neck pain - possible MI Severe leg pain, tenderness - possible thrombophlebitis Hemoptysis, acute Shortness of Breath - possible pulmonary embolism Hepatic mass, tenderness - possible hepatic neoplasm or adenoma
  • Not nausea
  • Some hormonal contraceptive side effects warrant further investigation while continuing the same method.
    • Immediate Evaluation to Continue if: Amenorrhea - possible pregnancy RUQ pain - possible cholecystitis, cholelithiasis Breast Mass- possible breast cancer Severe headache- possible stroke, migraine Galactorrhea- possible pituitary adenoma
  • Examples include amenorrhea (possible pregnancy), breast mass (possible cancer), RUQ pain (cholecystitis, cholelithiasis), severe headache (stroke, migraine headache), and galactorrhea (pituitary adenoma).
  • Combo pills prevent ovulation; if ovulation occurs, progesterone thickens cervical mucus, inhibiting sperm migration, and creating an atrophic endometrium.
  • Combo pills predominantly use estrogen and progesterone helping to regulate Cycles as well as produce less breakthrough bleeding.
  • Estrogen increases the efficacy of progesterone and stabilizes the endometrium.
  • Women over 35 who smoke; Hx of thromboembolism; Hx of CAD, CHF, CVA; Hx of migraine with or without aura are contraindications for combo pills.
  • The standard combo pill regime is 21 days of active pills, followed by 7 days of placebo pills. Continuous regimens produce shorter or less frequent menstrual periods - One period every 3 or 12 months.
  • Benefits of combo pills include shorter/less painful periods, lower incidence of endometrial/ovarian cancer, benign breast/ovarian diseases, pelvic infection, ectopic pregnancies.
  • Breakthrough bleeding occurs in roughly 10-30% of women using low-dose Ocs and usually resolves spontaneously.
  • Not Controlled HTN patients is not a contraindication

Safer Birth Control Pills

  • Nextstellis combines a novel estrogen, estetrol, with the progestin drospirenone and was approved by the FDA on April 16, 2021.
  • Estetrol is naturally occurring and produced from a plant source, unlike ethinyl estradiol.
  • A clinical trial found that an OC formulated with estetrol and drospirenone had substantially less impact on coagulation markers than an ethinyl estradiol-drospirenone or an ethinyl estradiol-levonorgestrel OC.

Non-prescription birth control

  • A new OCP(Opill) was approved and will be available in early 2024

Progestin Only Pills

  • Progestin-only pills ("mini pill") thicken cervical mucus, rendering it relatively impermeable.
  • Patients must always take the mini pill at approximately the same time every day; if more than 3 hours late, another form of birth control must be used for 48 hours.
  • Patient education regarding progestin-only pills: take at approximately the same time every day, starting on the 1st day of menses.
  • Mini pills area beneficial for use with lactating women, women over 40, and when estrogen formulas are contraindicated.
  • Not smokers

Transdermal Patch

  • Apply during the first 5 days of menses; replace weekly for 3 weeks, followed by a patch-free 4th week to allow for withdrawal bleeding
  • Patients place patch clean, dry skin (butt, upper outer arm, or lower abdomen).
  • A transdermal patch is a combo patch lasting 1 week.

Rings

  • Rings release same amount of hormones daily.
  • Rings are used once a month.
  • Inserted monthly (placed in the vagina at the start of menses and left in place for 3 weeks).
  • Withdrawal bleeding occurs upon ring removal.

Diaphragms

  • A diaphragm is a barrier method, dependent on proper use.
  • Dome-shaped latex device fitting over the anterior vaginal wall and cervix. Used with contraceptive jelly/cream
  • Fitted 6hrs prior to intercourse
    • Left in place for 6-8 hrs after, but not > 24 hrs
  • A side effect is a higher rate of UTIs.

Cervical Caps

  • A cervical cap works as a barrier method, dependent on proper use.
  • Covers only the cervix.
  • Easier to displace, harder to fit.
  • Higher incidence of toxic shock syndrome (TSS) and cervicitis.

Sponges

  • Contains spermicide.
  • Small, pillow-shaped sponge that fits over the cervix containing spermicide.
  • Can remain in place for 24 hours and is more effective in nulliparous women.
  • Increased risk of TSS if left in place for >30 hours.

Contraceptives - Condoms

  • Advise pts to seek medical care with 120 hrs if the condom slips/breaks so emergency contraceptive can happen
    • Two Types: sheaths worn over the penis and worn inside the vagina (female condom)
    • For either they must be left in place 6–8 hours after intercourse
    • Advise patients to seek emergency care within 120 hrs if it slips or breaks.

Long Acting Reversible Contraceptives

  • Long-acting reversible contraceptives include IUDs and hormone-eluting subdermal implants and is a 99% effective form of birth control Good options include, Those with contraindications to estrogen containing compounds Those who desire a rapid return to fertility or Have Higher up-front costs

IUDS

  • All IUDs must be checked for ideal placement after in 4 weeks
  • adolescents are ideal candidates to use as AAP
  • Contraindications include Congenital or Aquired or distortions of uterus Bicornuate or a septate fiberoids the CUB pregnancy and active are PID
  • Risks associated is increased incidence of PID, spontaneous expulsion as well as uterine incorporation.
  • Copper IUDs and Levonorgestrel releasing IUDs are available to use in the US
    • Hormonal thicken cervical mucus for the place where the first seven days a place of the LMP. Place side effect of the Irregular the spotting in Aminorhea A rise in and copper can use while breathfeeding it can also have a response to its toxic to speed over for printing your pregnancy.

Copper IUD

  • Copper IUD- ParaGard interferes withsperm motility and fertilization and may inhibit implantation
    • The Copper IUD can be used in breastfeeding mothers.
  • Copper IUD creates a cytotoxic response in the endometrium and may inhibit implantation of the embro

Depot Medroxyprogesterone

  • Depot medroxyprogesterone (Depo-Provera) is an injectable progestin given IM/SC every 3 mos within first 5 days of menses. Lasts for at least 14 wks (“safety margin").
  • It has an FDA warning has FDA over to years over bone loss

Etonogestrel

  • Etonogestrel (Nexplanon, Implanon), Insert it in other upper AR
  • It place to it's always and as in dysmenorrhea for those to contraindications that 3 yrs

Emergency Contraception

  • Must be used or the 7072
  • In patient EC
  • Plan B in OTC
  • Ella is Rx only
  • copper is most

Sterilization

  • Sterilization should be pretested.
  • Is always should be a long there.
  • Huldka method has be used.

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