Podcast
Questions and Answers
What is the primary mechanism of action of sulfonylureas?
What is the primary mechanism of action of sulfonylureas?
- Increasing peripheral insulin resistance
- Stimulation of insulin release by blocking ATP-sensitive K+ channels (correct)
- Inhibition of hepatic glucose production
- Enhancing gluconeogenesis in the liver
Which sulfonylurea has the shortest half-life?
Which sulfonylurea has the shortest half-life?
- Glyburide
- Repaglinide
- Glimepiride
- Glipizide (correct)
What adverse effect is commonly associated with sulfonylureas?
What adverse effect is commonly associated with sulfonylureas?
- Hypoglycemia (correct)
- Weight loss
- Hyperglycemia
- Hypercholesterolemia
Which sulfonylurea has minimal transfer across the placenta and can be used as an alternative to insulin during pregnancy?
Which sulfonylurea has minimal transfer across the placenta and can be used as an alternative to insulin during pregnancy?
In which conditions should sulfonylureas be used with caution due to the risk of hypoglycemia?
In which conditions should sulfonylureas be used with caution due to the risk of hypoglycemia?
What distinguishes Meglitidines from Sulfonylureas in terms of duration of action?
What distinguishes Meglitidines from Sulfonylureas in terms of duration of action?
Which of the following statements about Metformin is true?
Which of the following statements about Metformin is true?
What is a common side effect of α-glucosidase inhibitors like Acarbose and Miglitol?
What is a common side effect of α-glucosidase inhibitors like Acarbose and Miglitol?
Why should Acarbose and Miglitol be used with caution in combination with insulin secretagogues or insulin?
Why should Acarbose and Miglitol be used with caution in combination with insulin secretagogues or insulin?
What distinguishes Biguanides like Metformin from Sulfonylureas in terms of their mechanism of action?
What distinguishes Biguanides like Metformin from Sulfonylureas in terms of their mechanism of action?
Which group of medications is contraindicated in patients with irritable or inflammatory bowel disease?
Which group of medications is contraindicated in patients with irritable or inflammatory bowel disease?
What is a risk factor for hypoglycemia associated with Insulin Sensitizers like Metformin?
What is a risk factor for hypoglycemia associated with Insulin Sensitizers like Metformin?