17 Questions
What percentage of 'mild asthmatics' died from asthma events?
15-20%
What type of medication is used as a 'reliever' in asthma pharmacotherapy?
SABA
Which of the following is NOT a goal of asthma control?
Achieve normal body weight
What percentage of 'mild asthmatics' have near-fatal asthma events?
16%
What is the paradigm shift in focus for asthma management?
From treatment of presentation to asthma control
What is the primary target for reliever asthma therapy in bronchodilation?
B2-adrenergic receptors
What is the preferred agent for quick onset bronchodilation during asthma exacerbation?
Short acting β2-agonist
What is the mechanism of bronchodilation in asthma therapy?
Stimulation of B2-adrenergic receptors
What is the characteristic of fast-onset LABA + ICS as an alternative to short acting β2-agonists?
Limited by cost
What does the duration of action of a β2-agonist tell us about the dosing frequency of the agent?
The longer the duration, the less frequent the dosing
Do all LABAs have a delayed onset of action?
No, not all LABAs have a delayed onset of action
What is the primary mechanism of action of β2-agonists?
Activation of G-protein coupled receptors
What is the primary role of β2-agonists in asthma therapy?
Reliever medication
What is a common adverse effect of β2-agonists?
Tremor
How do inhaled corticosteroids act on the airways?
By binding to glucocorticoid response elements
What is the benefit of combining β2-agonists with inhaled corticosteroids?
Synergistic improvement in symptom control
What is a contraindication for the use of β2-agonists?
Hyperthyroidism
Learn about the different types of medications used to treat asthma, including relievers and controllers. Understand the mechanisms of bronchodilators and their effects on airways.
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