Asthma and Drugs Interaction Quiz

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Questions and Answers

What is the main difference between acute and chronic conditions?

  • Acute conditions always lead to irreversible harm, while chronic conditions only cause temporary issues.
  • Acute conditions are new complaints, while chronic conditions are usually present long-term. (correct)
  • Chronic conditions always have a higher mortality risk compared to acute conditions.
  • Acute conditions are usually present long-term, while chronic conditions are new complaints.

What does increasing mortality in a patient indicate?

  • No impact on the patient's health
  • Improved survival
  • Increased risk of death (correct)
  • Decreased risk of death

How are 'risk for toxicity' and 'toxicity' related?

  • 'Risk for toxicity' and 'toxicity' have the same meaning.
  • 'Risk for toxicity' always leads to irreversible harm, while 'toxicity' may be reversible.
  • 'Toxicity' is interchangeable with adverse effects (side effects), unlike 'risk for toxicity.'
  • 'Risk for toxicity' refers to the negative effects harming the patient, while 'toxicity' indicates conditions increasing this risk. (correct)

What is the main characteristic of Allergic Rhinitis?

<p>Characterized by hypersensitivity, exudation, hypersecretion, inflammatory cell infiltration, and remodeling (B)</p> Signup and view all the answers

In pharmacology, why is it important to be able to apply knowledge about medications?

<p>To make the safest &amp; most effective use of medications in patient care (A)</p> Signup and view all the answers

What does an acute on chronic presentation usually indicate?

<p>A new complaint occurring in a patient with a long-term existing condition (A)</p> Signup and view all the answers

Which medication prevents bronchoconstriction by blocking M3 receptors?

<p>Tiotropium (D)</p> Signup and view all the answers

Which drug class improves FEV1 and symptoms in COPD primarily through bronchial smooth muscle relaxation?

<p>Long-acting muscarinic antagonists (LAMAs) (D)</p> Signup and view all the answers

Which medication is NOT associated with the side effect of tremor in COPD treatment?

<p>Levalbuterol (D)</p> Signup and view all the answers

Which drug class inhibits NF-kB to exert its anti-inflammatory effects in COPD?

<p>Inhaled corticosteroids (D)</p> Signup and view all the answers

Which medication is considered central to symptom management in COPD due to its bronchodilatory effects?

<p>Ipratropium (D)</p> Signup and view all the answers

Which drug class is most beneficial in COPD if eosinophilia is present due to its mode of action?

<p>Inhaled Corticosteroids (ICS) (C)</p> Signup and view all the answers

What is the recommended pharmacological therapy for chronic control of asthma in all patients, except for those with specific triggers?

<p>Inhaled corticosteroids (A)</p> Signup and view all the answers

Which group of patients with asthma may benefit from Anti-Leukotrienes?

<p>Patients with an allergic component (D)</p> Signup and view all the answers

Why are Cromolyn and anti-muscarinic agents rarely used in asthma?

<p>They are ineffective in asthma treatment (B)</p> Signup and view all the answers

What is a key aspect of COPD assumptions regarding airway obstruction?

<p>Airway obstruction related to emphysema and chronic bronchitis (A)</p> Signup and view all the answers

What is the first step recommended for prevention and maintenance therapy in COPD management?

<p>Quitting smoking (D)</p> Signup and view all the answers

For what type of asthma patients are LABAs contraindicated for acute use?

<p>Patients with specific triggers (A)</p> Signup and view all the answers

What is the pharmacologic strategy for the treatment of severe acute asthma (status asthmaticus) or asthma exacerbation?

<p>Albuterol by nebulizer or metered dose inhalation (B)</p> Signup and view all the answers

Which class of drugs should be usually avoided in asthma due to causing bronchoconstriction?

<p>Histamine-releasing drugs (D)</p> Signup and view all the answers

What is the purpose of using methacholine in the context of asthma management?

<p>To diagnose hyper-reactivity of the airways (D)</p> Signup and view all the answers

What effect does aspirin have on prostaglandins in the context of asthma management?

<p>Blocks PGE2 &amp; promotes PGF2a (B)</p> Signup and view all the answers

Which drug may be administered if life-threatening bronchoconstriction is present in severe acute asthma?

<p>Epinephrine by IV or IM (C)</p> Signup and view all the answers

What is a common adverse effect of systemic anti-muscarinic drugs used in asthma?

<p>Airway constriction (A)</p> Signup and view all the answers

Which group(s) of COPD patients generally benefit from LABA?

<p>Both Group B and Group E (B)</p> Signup and view all the answers

What is the compelling indication for the use of inhaled corticosteroids (ICS) in COPD patients?

<p>Eosinophilia (B)</p> Signup and view all the answers

Which antimicrobial therapy is commonly used in hospitalized patients with acute exacerbation of COPD (ABECB)?

<p>Piperacillin + Tazobactam (A)</p> Signup and view all the answers

Which antibiotic decreases microbial cell wall synthesis via peptidoglycan cross-linking, similar to penicillin?

<p>Cefepime (A)</p> Signup and view all the answers

What is a common side effect of centrally-acting antitussives like codeine and dextromethorphan?

<p>Constipation (C)</p> Signup and view all the answers

Why are cough suppressants like codeine and dextromethorphan generally avoided in children under 2 years of age?

<p>They can cause jitters/irritability (B)</p> Signup and view all the answers

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