Asthma and Drugs Interaction Quiz

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What is the main difference between acute and chronic conditions?

Acute conditions always lead to irreversible harm, while chronic conditions only cause temporary issues.

Acute conditions are new complaints, while chronic conditions are usually present long-term. (correct)

Chronic conditions always have a higher mortality risk compared to acute conditions.

Acute conditions are usually present long-term, while chronic conditions are new complaints.

What does increasing mortality in a patient indicate?

No impact on the patient's health

Improved survival

Increased risk of death (correct)

Decreased risk of death

How are 'risk for toxicity' and 'toxicity' related?

'Risk for toxicity' and 'toxicity' have the same meaning.

'Risk for toxicity' always leads to irreversible harm, while 'toxicity' may be reversible.

'Toxicity' is interchangeable with adverse effects (side effects), unlike 'risk for toxicity.'

'Risk for toxicity' refers to the negative effects harming the patient, while 'toxicity' indicates conditions increasing this risk. (correct)

What is the main characteristic of Allergic Rhinitis?

Characterized by hypersensitivity, exudation, hypersecretion, inflammatory cell infiltration, and remodeling Signup and view all the answers

In pharmacology, why is it important to be able to apply knowledge about medications?

To make the safest & most effective use of medications in patient care Signup and view all the answers

What does an acute on chronic presentation usually indicate?

A new complaint occurring in a patient with a long-term existing condition Signup and view all the answers

Which medication prevents bronchoconstriction by blocking M3 receptors?

Tiotropium Signup and view all the answers

Which drug class improves FEV1 and symptoms in COPD primarily through bronchial smooth muscle relaxation?

Long-acting muscarinic antagonists (LAMAs) Signup and view all the answers

Which medication is NOT associated with the side effect of tremor in COPD treatment?

Levalbuterol Signup and view all the answers

Which drug class inhibits NF-kB to exert its anti-inflammatory effects in COPD?

Inhaled corticosteroids Signup and view all the answers

Which medication is considered central to symptom management in COPD due to its bronchodilatory effects?

Ipratropium Signup and view all the answers

Which drug class is most beneficial in COPD if eosinophilia is present due to its mode of action?

Inhaled Corticosteroids (ICS) Signup and view all the answers

What is the recommended pharmacological therapy for chronic control of asthma in all patients, except for those with specific triggers?

Inhaled corticosteroids Signup and view all the answers

Which group of patients with asthma may benefit from Anti-Leukotrienes?

Patients with an allergic component Signup and view all the answers

Why are Cromolyn and anti-muscarinic agents rarely used in asthma?

They are ineffective in asthma treatment Signup and view all the answers

What is a key aspect of COPD assumptions regarding airway obstruction?

Airway obstruction related to emphysema and chronic bronchitis Signup and view all the answers

What is the first step recommended for prevention and maintenance therapy in COPD management?

Quitting smoking Signup and view all the answers

For what type of asthma patients are LABAs contraindicated for acute use?

Patients with specific triggers Signup and view all the answers

What is the pharmacologic strategy for the treatment of severe acute asthma (status asthmaticus) or asthma exacerbation?

Albuterol by nebulizer or metered dose inhalation Signup and view all the answers

Which class of drugs should be usually avoided in asthma due to causing bronchoconstriction?

Histamine-releasing drugs Signup and view all the answers

What is the purpose of using methacholine in the context of asthma management?

To diagnose hyper-reactivity of the airways Signup and view all the answers

What effect does aspirin have on prostaglandins in the context of asthma management?

Blocks PGE2 & promotes PGF2a Signup and view all the answers

Which drug may be administered if life-threatening bronchoconstriction is present in severe acute asthma?

Epinephrine by IV or IM Signup and view all the answers

What is a common adverse effect of systemic anti-muscarinic drugs used in asthma?

Airway constriction Signup and view all the answers

Which group(s) of COPD patients generally benefit from LABA?

Both Group B and Group E Signup and view all the answers

What is the compelling indication for the use of inhaled corticosteroids (ICS) in COPD patients?

Eosinophilia Signup and view all the answers

Which antimicrobial therapy is commonly used in hospitalized patients with acute exacerbation of COPD (ABECB)?

Piperacillin + Tazobactam Signup and view all the answers

Which antibiotic decreases microbial cell wall synthesis via peptidoglycan cross-linking, similar to penicillin?

Cefepime Signup and view all the answers

What is a common side effect of centrally-acting antitussives like codeine and dextromethorphan?

Constipation Signup and view all the answers

Why are cough suppressants like codeine and dextromethorphan generally avoided in children under 2 years of age?

They can cause jitters/irritability Signup and view all the answers