Drug Testing Methods for Hypertension and Asthma
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Questions and Answers

Which step is NOT involved in understanding disease and testing drugs?

  • Testing drugs for activity in vitro
  • Producing a model disease in animals
  • Having a simple system for looking at relevant activity
  • Testing drugs for activity in vivo (correct)

Which activity is NOT tested in a simple system to understand disease?

  • Reversing an agent that causes bronchoconstriction in vivo
  • Lowering blood pressure in normal animals (correct)
  • Relaxing blood vessels in vitro
  • Relaxing airway muscles in vitro

What is the risk of false positives in disease models?

  • Agents that might have been active in disease but are rejected
  • Agents that resemble human disease
  • Agents that are only models
  • Agents that are active in model but inactive in disease (correct)

What is the risk of false negatives in disease models?

<p>Agents that might have been active in disease but are rejected (B)</p> Signup and view all the answers

Why is it important to show that existing drugs work in model diseases?

<p>To understand mechanisms of existing drugs (A)</p> Signup and view all the answers

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