Podcast
Questions and Answers
Which step is NOT involved in understanding disease and testing drugs?
Which step is NOT involved in understanding disease and testing drugs?
- Testing drugs for activity in vitro
- Producing a model disease in animals
- Having a simple system for looking at relevant activity
- Testing drugs for activity in vivo (correct)
Which activity is NOT tested in a simple system to understand disease?
Which activity is NOT tested in a simple system to understand disease?
- Reversing an agent that causes bronchoconstriction in vivo
- Lowering blood pressure in normal animals (correct)
- Relaxing blood vessels in vitro
- Relaxing airway muscles in vitro
What is the risk of false positives in disease models?
What is the risk of false positives in disease models?
- Agents that might have been active in disease but are rejected
- Agents that resemble human disease
- Agents that are only models
- Agents that are active in model but inactive in disease (correct)
What is the risk of false negatives in disease models?
What is the risk of false negatives in disease models?
Why is it important to show that existing drugs work in model diseases?
Why is it important to show that existing drugs work in model diseases?