ASPIRIN Trial: Low-dose Aspirin for Preterm Delivery Prevention

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Questions and Answers

What was the main focus of the study described in the text?

  • Analyzing the benefits of high-dose aspirin in pregnant women
  • Evaluating the impact of low-dose aspirin on cardiovascular health
  • Comparing the side effects of different pain medications on women
  • Investigating the effect of low-dose aspirin on preterm birth in women (correct)

What was the percentage of preterm births before 37 weeks among women who took placebo?

  • 11.6%
  • 13.1% (correct)
  • 12.3%
  • 10.8%

Which outcome showed a significant reduction in women who took aspirin compared to placebo?

  • Prolonged labor
  • Multiple gestations
  • Gestational diabetes
  • Perinatal mortality (correct)

What term is used to describe infant death after 16 weeks’ gestation and before 7 days post partum?

<p>Neonatal death (A)</p> Signup and view all the answers

What was the primary outcome measured in the ASPIRIN trial?

<p>Incidence of preterm birth before 37 weeks of gestation (D)</p> Signup and view all the answers

How were participants randomly assigned to treatment groups in the ASPIRIN trial?

<p>1:1 ratio of aspirin to placebo, stratified by site (A)</p> Signup and view all the answers

When were participants enrolled in the ASPIRIN trial?

<p>Between 6 weeks and 13 weeks 6 days of pregnancy (C)</p> Signup and view all the answers

Which population was included in the ASPIRIN trial?

<p>Nulliparous women with singleton pregnancies (C)</p> Signup and view all the answers

In which countries were study sites for the ASPIRIN trial located?

<p>India, Democratic Republic of the Congo, Guatemala, Kenya, Pakistan, Zambia (D)</p> Signup and view all the answers

Which statement regarding preterm birth is true, according to the information provided?

<p>Preterm birth remains a common cause of neonatal mortality, with a higher burden in low-income and middle-income countries (A)</p> Signup and view all the answers

What was the primary objective of the ASPIRIN study?

<p>To investigate the use of low-dose aspirin in preventing preterm delivery in nulliparous women with a singleton pregnancy (C)</p> Signup and view all the answers

What type of study design was used in the ASPIRIN trial?

<p>Randomized, double-blind, placebo-controlled trial (B)</p> Signup and view all the answers

Which of the following statements is NOT true about the study population in the ASPIRIN trial?

<p>The study excluded women with a history of previous preterm births (D)</p> Signup and view all the answers

What was the primary intervention being evaluated in the ASPIRIN trial?

<p>Administration of low-dose aspirin (D)</p> Signup and view all the answers

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