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ASPIRIN Trial: Low-dose Aspirin for Preterm Delivery Prevention

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ASPIRIN Trial: Low-dose Aspirin for Preterm Delivery Prevention

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Questions and Answers

What was the main focus of the study described in the text?

Analyzing the benefits of high-dose aspirin in pregnant women

Evaluating the impact of low-dose aspirin on cardiovascular health

Comparing the side effects of different pain medications on women

Investigating the effect of low-dose aspirin on preterm birth in women (correct)

What was the percentage of preterm births before 37 weeks among women who took placebo?

11.6%

13.1% (correct)

12.3%

10.8%

Which outcome showed a significant reduction in women who took aspirin compared to placebo?

Prolonged labor

Multiple gestations

Gestational diabetes

Perinatal mortality (correct)

What term is used to describe infant death after 16 weeks’ gestation and before 7 days post partum?

Neonatal death Signup and view all the answers

What was the primary outcome measured in the ASPIRIN trial?

Incidence of preterm birth before 37 weeks of gestation Signup and view all the answers

How were participants randomly assigned to treatment groups in the ASPIRIN trial?

1:1 ratio of aspirin to placebo, stratified by site Signup and view all the answers

When were participants enrolled in the ASPIRIN trial?

Between 6 weeks and 13 weeks 6 days of pregnancy Signup and view all the answers

Which population was included in the ASPIRIN trial?

Nulliparous women with singleton pregnancies Signup and view all the answers

In which countries were study sites for the ASPIRIN trial located?

India, Democratic Republic of the Congo, Guatemala, Kenya, Pakistan, Zambia Signup and view all the answers

Which statement regarding preterm birth is true, according to the information provided?

Preterm birth remains a common cause of neonatal mortality, with a higher burden in low-income and middle-income countries Signup and view all the answers

What was the primary objective of the ASPIRIN study?

To investigate the use of low-dose aspirin in preventing preterm delivery in nulliparous women with a singleton pregnancy Signup and view all the answers

What type of study design was used in the ASPIRIN trial?

Randomized, double-blind, placebo-controlled trial Signup and view all the answers

Which of the following statements is NOT true about the study population in the ASPIRIN trial?

The study excluded women with a history of previous preterm births Signup and view all the answers

What was the primary intervention being evaluated in the ASPIRIN trial?

Administration of low-dose aspirin Signup and view all the answers