ASPIRIN Trial: Low-dose Aspirin for Preterm Delivery Prevention

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14 Questions

What was the main focus of the study described in the text?

Investigating the effect of low-dose aspirin on preterm birth in women

What was the percentage of preterm births before 37 weeks among women who took placebo?

13.1%

Which outcome showed a significant reduction in women who took aspirin compared to placebo?

Perinatal mortality

What term is used to describe infant death after 16 weeks’ gestation and before 7 days post partum?

Neonatal death

What was the primary outcome measured in the ASPIRIN trial?

Incidence of preterm birth before 37 weeks of gestation

How were participants randomly assigned to treatment groups in the ASPIRIN trial?

1:1 ratio of aspirin to placebo, stratified by site

When were participants enrolled in the ASPIRIN trial?

Between 6 weeks and 13 weeks 6 days of pregnancy

Which population was included in the ASPIRIN trial?

Nulliparous women with singleton pregnancies

In which countries were study sites for the ASPIRIN trial located?

India, Democratic Republic of the Congo, Guatemala, Kenya, Pakistan, Zambia

Which statement regarding preterm birth is true, according to the information provided?

Preterm birth remains a common cause of neonatal mortality, with a higher burden in low-income and middle-income countries

What was the primary objective of the ASPIRIN study?

To investigate the use of low-dose aspirin in preventing preterm delivery in nulliparous women with a singleton pregnancy

What type of study design was used in the ASPIRIN trial?

Randomized, double-blind, placebo-controlled trial

Which of the following statements is NOT true about the study population in the ASPIRIN trial?

The study excluded women with a history of previous preterm births

What was the primary intervention being evaluated in the ASPIRIN trial?

Administration of low-dose aspirin

This quiz covers the results and findings of the ASPIRIN trial, a randomized, double-blind, placebo-controlled study focusing on the use of low-dose aspirin for preventing preterm delivery in nulliparous women with a singleton pregnancy. The trial was conducted by various healthcare professionals and researchers.

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