Aspirin Therapeutic Effects and Actions
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Questions and Answers

What are the therapeutic effects of Aspirin? (Select all that apply)

  • Decreased incidence of transient ischemic attacks and MI (correct)
  • Analgesia (correct)
  • Reduction of inflammation (correct)
  • Increase of blood pressure

What is the action of Aspirin?

Thought to produce analgesia and exert its anti-inflammatory effect by inhibiting prostaglandin and other substances that sensitize pain receptors.

What are the classifications of Aspirin?

  • Therapeutic class: Analgesics
  • Pharmacologic class: Salicylates (correct)
  • Pharmacologic class: NSAIDs
  • Pregnancy risk: C; D if used full dose in third trimester (correct)

Aspirin may increase liver function test values, BUN, creatinine, and potassium levels.

<p>True (A)</p> Signup and view all the answers

What are the routes of Aspirin?

<p>P.O.- non-enteric-coated and rectal: suppositories.</p> Signup and view all the answers

What are the specific nursing interventions for administering Aspirin?

<p>Give drug with food, milk, antacid, or a large glass of water to reduce GI effects.</p> Signup and view all the answers

What are the side effects of Aspirin? (Select all that apply)

<p>GI reaction (A), Small round red pinprick spots (B), Bleeding gums (D)</p> Signup and view all the answers

What are the cautions of Aspirin?

<p>Use cautiously in patients hypersensitive to the drug, with NSAID induced sensitivity, G6PD deficiency, bleeding disorders, or GI problems.</p> Signup and view all the answers

What are the symptoms of Aspirin overdose? (Select all that apply)

<p>Tinnitus (A), Severe acid-base imbalance (B), Hyperventilation (D)</p> Signup and view all the answers

What are the Nurse teachings regarding Aspirin?

<p>Avoid Aspirin if allergic to tartrazine, take with food or milk, check with prescriber before regular use, and avoid during the last trimester of pregnancy.</p> Signup and view all the answers

Flashcards

Aspirin's therapeutic effects

Aspirin reduces pain, inflammation, and fever, and lowers risk of heart attacks and strokes.

Aspirin's action mechanism

Aspirin blocks the production of prostaglandins, reducing pain and inflammation.

Aspirin's classifications

Aspirin is a salicylate and NSAID, with pregnancy concerns (Category C or D).

Aspirin's lab interferences

Aspirin can affect lab results (liver, kidney, blood counts, etc.).

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Aspirin administration routes

Aspirin is typically taken orally and can also be used rectally.

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Aspirin administration tips

Take aspirin with food/drinks to protect stomach, and refrigerate suppositories.

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Aspirin's side effects

Potential stomach issues and skin reactions may occur.

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Aspirin's cautions

Avoid in allergies, G6PD deficiency, and bleeding problems.

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Aspirin overdose symptoms

Overdose can cause severe side effects like acid-base imbalances, confusion, and discomfort.

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Nurse teaching on aspirin use

Counsel patients about proper use, potential risks, and when to seek medical help.

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Study Notes

Therapeutic Effects of Aspirin

  • Provides analgesia, reducing pain.
  • Anti-inflammatory properties help decrease inflammation.
  • Reduces fever, aiding in the management of pyrexia.
  • Lowers the incidence of transient ischemic attacks and myocardial infarctions (MI).

Action Mechanism of Aspirin

  • Inhibits the production of prostaglandins, substances that sensitize pain receptors.
  • Relieves fever by acting on the hypothalamic heat-regulating center.
  • In low doses, prevents platelet aggregation, thereby interfering with blood clotting.

Classifications of Aspirin

  • Pharmacologic class: Salicylates.
  • Therapeutic class: Nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Pregnancy risk: Category C; Category D if used at full dose in the third trimester.

Laboratory Interferences Caused by Aspirin

  • May elevate liver function tests, blood urea nitrogen (BUN), creatinine, and potassium levels.
  • Can decrease platelet and white blood cell (WBC) counts.
  • Alters protein-bound iodine levels, possibly increasing them.
  • Interferes with urine glucose analysis and certain urinary tests, affecting the accuracy of results.

Routes of Administration for Aspirin

  • Administered orally (P.O.), non-enteric-coated.
  • Available rectally as suppositories.

Nursing Interventions for Aspirin Administration

  • Administer with food, milk, antacids, or a large glass of water to minimize gastrointestinal side effects.
  • Sustained-release (SR) or enteric-coated (EC) forms should be given whole.
  • Refrigerate rectal suppositories prior to administration.

Side Effects of Aspirin

  • Potential gastrointestinal reactions, including discomfort and irritation.
  • Possible appearance of small round red pinprick spots on the skin.
  • Symptoms may include bleeding gums.

Cautions and Contraindications for Aspirin

  • Avoid in patients with hypersensitivity to NSAIDs or a history of induced sensitivity reactions.
  • Use cautiously in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency or bleeding disorders.
  • Should be administered with care to patients with gastrointestinal issues.

Symptoms of Aspirin Overdose

  • Causes severe acid-base and electrolyte disturbances.
  • Symptoms may include hyperthermia, dehydration, tinnitus, vertigo, headache, and confusion.
  • Additional signs: drowsiness, diaphoresis, hyperventilation, vomiting, and diarrhea.
  • Advise avoiding aspirin if allergic to tartrazine.
  • Emphasize taking the medication with food, milk, antacid, or a large glass of water.
  • Recommend consulting a healthcare provider prior to regular aspirin use.
  • Pregnant women should avoid aspirin during the last trimester due to potential risks.

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Description

This quiz explores the therapeutic effects and mechanisms of action of Aspirin. It provides key insights into how Aspirin works as an analgesic, anti-inflammatory, and antipyretic agent. Test your knowledge of this common medication's benefits and functions!

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