Aspirin Therapeutic Effects and Actions
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Questions and Answers

What are the therapeutic effects of Aspirin? (Select all that apply)

  • Decreased incidence of transient ischemic attacks and MI (correct)
  • Analgesia (correct)
  • Reduction of inflammation (correct)
  • Increase of blood pressure
  • What is the action of Aspirin?

    Thought to produce analgesia and exert its anti-inflammatory effect by inhibiting prostaglandin and other substances that sensitize pain receptors.

    What are the classifications of Aspirin?

  • Therapeutic class: Analgesics
  • Pharmacologic class: Salicylates (correct)
  • Pharmacologic class: NSAIDs
  • Pregnancy risk: C; D if used full dose in third trimester (correct)
  • Aspirin may increase liver function test values, BUN, creatinine, and potassium levels.

    <p>True</p> Signup and view all the answers

    What are the routes of Aspirin?

    <p>P.O.- non-enteric-coated and rectal: suppositories.</p> Signup and view all the answers

    What are the specific nursing interventions for administering Aspirin?

    <p>Give drug with food, milk, antacid, or a large glass of water to reduce GI effects.</p> Signup and view all the answers

    What are the side effects of Aspirin? (Select all that apply)

    <p>GI reaction</p> Signup and view all the answers

    What are the cautions of Aspirin?

    <p>Use cautiously in patients hypersensitive to the drug, with NSAID induced sensitivity, G6PD deficiency, bleeding disorders, or GI problems.</p> Signup and view all the answers

    What are the symptoms of Aspirin overdose? (Select all that apply)

    <p>Tinnitus</p> Signup and view all the answers

    What are the Nurse teachings regarding Aspirin?

    <p>Avoid Aspirin if allergic to tartrazine, take with food or milk, check with prescriber before regular use, and avoid during the last trimester of pregnancy.</p> Signup and view all the answers

    Study Notes

    Therapeutic Effects of Aspirin

    • Provides analgesia, reducing pain.
    • Anti-inflammatory properties help decrease inflammation.
    • Reduces fever, aiding in the management of pyrexia.
    • Lowers the incidence of transient ischemic attacks and myocardial infarctions (MI).

    Action Mechanism of Aspirin

    • Inhibits the production of prostaglandins, substances that sensitize pain receptors.
    • Relieves fever by acting on the hypothalamic heat-regulating center.
    • In low doses, prevents platelet aggregation, thereby interfering with blood clotting.

    Classifications of Aspirin

    • Pharmacologic class: Salicylates.
    • Therapeutic class: Nonsteroidal anti-inflammatory drugs (NSAIDs).
    • Pregnancy risk: Category C; Category D if used at full dose in the third trimester.

    Laboratory Interferences Caused by Aspirin

    • May elevate liver function tests, blood urea nitrogen (BUN), creatinine, and potassium levels.
    • Can decrease platelet and white blood cell (WBC) counts.
    • Alters protein-bound iodine levels, possibly increasing them.
    • Interferes with urine glucose analysis and certain urinary tests, affecting the accuracy of results.

    Routes of Administration for Aspirin

    • Administered orally (P.O.), non-enteric-coated.
    • Available rectally as suppositories.

    Nursing Interventions for Aspirin Administration

    • Administer with food, milk, antacids, or a large glass of water to minimize gastrointestinal side effects.
    • Sustained-release (SR) or enteric-coated (EC) forms should be given whole.
    • Refrigerate rectal suppositories prior to administration.

    Side Effects of Aspirin

    • Potential gastrointestinal reactions, including discomfort and irritation.
    • Possible appearance of small round red pinprick spots on the skin.
    • Symptoms may include bleeding gums.

    Cautions and Contraindications for Aspirin

    • Avoid in patients with hypersensitivity to NSAIDs or a history of induced sensitivity reactions.
    • Use cautiously in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency or bleeding disorders.
    • Should be administered with care to patients with gastrointestinal issues.

    Symptoms of Aspirin Overdose

    • Causes severe acid-base and electrolyte disturbances.
    • Symptoms may include hyperthermia, dehydration, tinnitus, vertigo, headache, and confusion.
    • Additional signs: drowsiness, diaphoresis, hyperventilation, vomiting, and diarrhea.
    • Advise avoiding aspirin if allergic to tartrazine.
    • Emphasize taking the medication with food, milk, antacid, or a large glass of water.
    • Recommend consulting a healthcare provider prior to regular aspirin use.
    • Pregnant women should avoid aspirin during the last trimester due to potential risks.

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    Description

    This quiz explores the therapeutic effects and mechanisms of action of Aspirin. It provides key insights into how Aspirin works as an analgesic, anti-inflammatory, and antipyretic agent. Test your knowledge of this common medication's benefits and functions!

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