59 Questions
What is the generic name for Aspirin?
Acetylsalicylic Acid
Which of the following is a contraindication for Aspirin?
Active bleeding
What is the mechanism of action for Aspirin?
Blocks the formation of thromboxane A and inhibits platelet aggregation
What is the first-line agent for treating pulmonary edema from congestive heart failure?
Nitroglycerin
What is the recommended dosage of Nitroglycerin for an adult with chest pain?
0.4 mg (2% solution) SL spray
Which of the following is a contraindication for Nitroglycerin?
Hypotension
What is the mechanism of action for Nitroglycerin?
Vascular smooth muscle relaxation
What is the recommended dosage of Nitroglycerin for an adult with pulmonary edema from congestive heart failure?
10-20 mcg/min IV drip
What is the recommended dosage of Aspirin for an adult with chest pain, myocardial infarction, or unstable angina?
162-324 mg PO
What is the recommended dosage of Nitroglycerin for a pediatric patient?
No prehospital administration suggested
What is the generic name for Pressin?
Vasopressin
Which of the following is NOT a contraindication or caution for atropine?
Hypothermic bradycardia
What is the maximum adult dose of atropine for cardiac indications?
3.0 mg
Which of the following is NOT a serious adverse reaction of vasopressin?
Hyperkalemia
What is the pediatric dose of atropine for organophosphate poisoning in children under 12 years old?
0.05 mg/kg IVP initially, repeat doubling dose q 5 min until muscarinic symptoms reverse
What is the indication for vasopressin according to the ACLS algorithm?
Alternative to epinephrine for ventricular fibrillation
Which of the following is NOT a mechanism of action for atropine?
Causes vasoconstriction
What is the adult dosage of vasopressin?
40 units IV push single dose only
Which of the following is NOT a common adverse reaction of vasopressin?
Hypoglycemia
What is the minimum dose of atropine for pediatric cardiac indications?
0.1 mg
Which of the following is a serious adverse reaction of Aspirin (Acetylsalicylic Acid)?
GI bleeding
What is the mechanism of action of Nitroglycerin?
Vascular smooth muscle relaxation
Which of the following is a contraindication for Aspirin (Acetylsalicylic Acid)?
Active GI ulcers
What is the recommended adult dosage of Nitroglycerin for chest pain or angina?
0.4mg SL spray or tablet every 3-5 minutes
Which of the following is a contraindication for Nitroglycerin?
All of the above
What is the recommended adult dosage of Aspirin (Acetylsalicylic Acid) for chest pain, myocardial infarction, or unstable angina?
162-324mg PO
Which of the following is a serious adverse reaction of Nitroglycerin?
Hypotension
What is the generic name for Nitrostat, Nitrospan, Nitrodisc, Nitrodur, and Tridil?
Nitroglycerin
Which of the following is a less serious adverse reaction of Aspirin (Acetylsalicylic Acid)?
Nausea
What is the classification of Nitroglycerin?
Nitrate, Vasodilator
Which of the following is NOT a consideration for the use of vasopressin?
It should be administered as a continuous infusion
Which of the following is a serious adverse reaction associated with vasopressin?
Myocardial infarction
What is the mechanism of action for vasopressin?
All of the above
Which of the following is a contraindication for the use of atropine?
All of the above
What is the mechanism of action for atropine?
All of the above
Which of the following is NOT an indication for atropine?
Supraventricular tachycardia
What is the maximum adult dose of atropine for cardiac indications?
3 mg
Which of the following is a common adverse reaction of atropine?
All of the above
What is the minimum dose of atropine for pediatric cardiac indications?
0.02 mg/kg
Which of the following is a consideration for the use of atropine?
All of the above
What is the primary classification of Aspirin (Acetylsalicylic Acid)?
Analgesic
Which of the following best describes the indication for Nitroglycerin?
Chest Pain
What is a common adverse reaction associated with Aspirin (Acetylsalicylic Acid)?
Bronchospasm
Which of the following is a serious adverse reaction to Nitroglycerin?
Hypotension
What action does Aspirin (Acetylsalicylic Acid) have on platelets?
Inhibits aggregation
Which condition is Aspirin (Acetylsalicylic Acid) relatively contraindicated with?
Pregnancy
What is the primary action mechanism of Nitroglycerin?
Relaxes vascular smooth muscle
Which of the following is a less serious adverse reaction to Nitroglycerin?
Tinnitus
What is a common adverse reaction associated with Nitroglycerin?
Headache
What is the mechanism of action for vasopressin that causes uterine contractions in large doses?
Naturally occurring hormone - ADH released from pituitary
Which of the following is a serious adverse reaction associated with atropine administration?
Paradoxical bradycardia if given too slowly
What is the recommended maximum adult dose of atropine for cardiac indications?
3 mg
Which of the following is a contraindication for the use of atropine?
Angle-closure glaucoma
Which of the following is NOT a mechanism of action for atropine?
Inhibiting insulin secretion
What is the recommended adult dosage of vasopressin according to the ACLS algorithm for ventricular fibrillation?
40 units IV push as a single dose only
Which of the following is a common adverse reaction associated with vasopressin administration?
Abdominal cramps
Which of the following is a contraindication or caution for the use of atropine?
All of the above
What is the mechanism of action for atropine that causes relaxation of smooth muscle in the bronchial tree?
Parasympatholytic effect
Which of the following is a serious adverse reaction associated with vasopressin administration?
Hypertension
Study Notes
-
Vasopressin:
- Trade Name: Pressin
- Generic Name: Vasopressin
- Classification: Vasopressor, similar to catecholamine
- Indication: Alternative to epinephrine in ACLS algorithm for Ventricular fib
- Dosage: Adult 40 units IV Push single dose only
- Action Mechanism: Natural hormone - ADH released from pituitary, non-adrenergic peripheral vasoconstrictor, increases water absorption in renal tubules, causes uterine contractions
- Adverse Reactions: Serious - MI, bradycardia, angina; Common - abdominal cramps, N/V, tremors, headache
-
Atropine:
- Trade Name: Atropine
- Generic Name: Atropine
- Classification: Anticholinergic
- Indication: Hemodynamically compromised symptomatic bradycardia (non-AMI), other specific conditions
- Dosage: Adult 1.0 mg rapid IVP q 3-5 min up to max 3 mg or 0.04 mg/kg
- Action Mechanism: Parasympatholytic, increases myocardial oxygen demand, relaxes smooth muscle in GI tract, causes bronchial relaxation
- Adverse Reactions: Serious - paradoxical bradycardia if given too slowly or below minimum dose, dry mouth, blurred vision, tachycardia
-
Aspirin:
- Trade Name: Aspirin
- Generic Name: Acetylsalicylic Acid
- Classification: Antiplatelet, non-narcotic analgesic, antipyretic
- Indication: Cardiac chest pain, angina, AMI, fever, inflammation
- Dosage: Adult 162-324 mg PO for chest pain/MI/unstable angina
- Action Mechanism: Blocks thromboxane A formation, inhibits platelet aggregation
- Adverse Reactions: Serious - GI bleeding, anaphylaxis; Common - nausea, vomiting, rash
-
Nitroglycerin:
- Trade Names: Nitrostat, Nitrospan, Nitrodisc, Nitrodur, Tridil
- Generic Name: Nitroglycerin
- Classification: Nitrate, Vasodilator
- Indication: Chest Pain/Angina, MI, pulmonary edema from CHF
- Dosage: Adult 0.4mg SL spray or tablet q. 3-5 minutes; IV drip at 10-20 mcg/min
- Action Mechanism: Vascular smooth muscle relaxation, decreases preload and myocardial O2 demand, coronary artery dilation
- Adverse Reactions: Serious - hypotension, bradycardia; Common - headache, lightheadedness
Test your knowledge on Aspirin and Acetylsalicylic Acid with questions on classification, indications, dosages, contraindications, and action mechanism.
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