Aspergillus Fungi and Associated Diseases
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Questions and Answers

Which type of hypersensitivity is associated with allergic bronchopulmonary aspergillosis (ABPA)?

  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type I hypersensitivity (correct)
  • Type IV hypersensitivity
  • What is the characteristic of the branching pattern of Aspergillus?

  • Acute branching with septations (correct)
  • Obtuse branching with septations
  • Right-angled branching without septations
  • Obtuse branching without septations
  • What is the name of the fruiting bodies produced by Aspergillus?

  • Conidiophores (correct)
  • Hyphae
  • Sporangia
  • Aspergillomas
  • Which of the following is a characteristic of aspergillomas?

    <p>They are gravity-dependent and found at the bottom of cavities</p> Signup and view all the answers

    What is the name of the antifungal medication used to treat less serious Aspergillus infections?

    <p>Voriconazole</p> Signup and view all the answers

    Which of the following conditions increases the susceptibility to aspergillosis?

    <p>Tuberculosis</p> Signup and view all the answers

    What is the primary source of fungal infection in humans?

    <p>Inhaling spores from the environment</p> Signup and view all the answers

    What is the typical location of aspergillomas in the lung?

    <p>At the base of the lung</p> Signup and view all the answers

    Which of the following is a risk factor for angioinvasive aspergillosis?

    <p>Neutropenia from leukemia or lymphoma</p> Signup and view all the answers

    What is a common complication of invasive aspergillosis?

    <p>Kidney failure</p> Signup and view all the answers

    What is the association between peanuts and Aspergillus flavus?

    <p>Peanuts are a common food source contaminated with Aspergillus flavus</p> Signup and view all the answers

    What is the characteristic morphology of Aspergillus?

    <p>Acute branching with septations</p> Signup and view all the answers

    Study Notes

    Aspergillus Fumigatus

    • Aspergillus has acute branching with septations

    Risk Factors and Associations

    • Peanuts are associated with aflatoxins produced by Aspergillus flavus
    • Aflatoxins are also associated with grains
    • Hepatocellular carcinoma is associated with Aspergillus infection

    Infections and Clinical Features

    • Allergic bronchopulmonary aspergillosis (ABPA) causes wheezing, fever, and migratory pulmonary infiltrate
    • Susceptibility to aspergillosis increases with TB cavities
    • Aspergillosis can cause aspergillomas, which are gravity-dependent and typically form at the bottom of cavities

    Angioinvasive Aspergillosis

    • Occurs in patients with neutropenia, often due to leukemia or lymphoma
    • Invades blood vessels and surrounding tissues
    • Can cause kidney failure, endocarditis, and ring-enhancing lesions in the brain
    • Can invade nasal sinuses

    Treatment

    • Voriconazole is used for less serious infections
    • Amphotericin B is used for angioinvasive disease

    Diagnosis

    • Histology is the best way to identify Aspergillus, characterized by 45-degree branching septae

    Aspergillus Fumigatus

    • Aspergillus has acute branching with septations

    Risk Factors and Associations

    • Peanuts are associated with aflatoxins produced by Aspergillus flavus
    • Aflatoxins are also associated with grains
    • Hepatocellular carcinoma is associated with Aspergillus infection

    Infections and Clinical Features

    • Allergic bronchopulmonary aspergillosis (ABPA) causes wheezing, fever, and migratory pulmonary infiltrate
    • Susceptibility to aspergillosis increases with TB cavities
    • Aspergillosis can cause aspergillomas, which are gravity-dependent and typically form at the bottom of cavities

    Angioinvasive Aspergillosis

    • Occurs in patients with neutropenia, often due to leukemia or lymphoma
    • Invades blood vessels and surrounding tissues
    • Can cause kidney failure, endocarditis, and ring-enhancing lesions in the brain
    • Can invade nasal sinuses

    Treatment

    • Voriconazole is used for less serious infections
    • Amphotericin B is used for angioinvasive disease

    Diagnosis

    • Histology is the best way to identify Aspergillus, characterized by 45-degree branching septae

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    Description

    This quiz covers various aspects of Aspergillus fungi, including their characteristics, associated diseases, and food associations. Identify the different species and their connections to food and health.

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