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A.S Metabolism of Ammonia Overview

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Questions and Answers

What is the role of N-acetyl glutamate in the urea cycle?

Regulating the transport of ornithine across the mitochondrial membrane
Allosterically activating carbamoyl phosphate synthase 1 (correct)
Promoting the conversion of ornithine to citrulline
Inhibiting carbamoyl phosphate synthase 1

What is the result of a defect in the ornithine transporter in the urea cycle?

Hyperammonemia due to increased ornithine transport
Homocitrullinuria due to abnormal ornithine metabolism
Hyperornithinemia due to decreased ornithine transport (correct)
Hyperammonemia due to decreased ornithine transport

What is the primary source of CO2 for urea formation in the urea cycle?

The citric acid cycle (TCA) (correct)
The electron transport chain
Glycolysis
The pentose phosphate pathway

What is the normal level of ammonia in the blood?

Below 0.05 mg/dl (D) Signup and view all the answers

What is the relationship between the urea cycle and the citric acid cycle (TCA)?

The TCA provides CO2 for the urea cycle (C) Signup and view all the answers

What is the result of a liver cell dysfunction in the urea cycle?

Decreased conversion of ammonia to urea (C) Signup and view all the answers

What is the function of carbamoyl phosphate synthase 1 in the urea cycle?

Converting ammonia to carbamoyl phosphate (C) Signup and view all the answers

What is the relationship between arginine and the urea cycle?

Arginine promotes the urea cycle (A) Signup and view all the answers

What is the result of homocitrullinuria?

Abnormal production of homocitrulline (B) Signup and view all the answers

What is the role of ATP in the urea cycle?

To provide energy for the urea cycle (D) Signup and view all the answers