5 Questions
What are the main pathways of temporary ammonia detoxification?
Synthesis of glutamine, synthesis of asparagine, reductive amination of α-ketoglutarate, transreamination, and the glucose-alanine cycle.
What are the main pathways of ammonia formation?
Temporary reductive amination of α-ketoglutarate, transreamination, synthesis of glutamine, synthesis of asparagine, and the glucose-alanine cycle.
How is glutamine transported to the liver and kidneys for detoxification?
With bloodstream glutamine is transported to the liver and kidneys.
What is formed in muscles during the glucose-alanine cycle?
Pyruvate.
What inhibits the enzyme glutamine synthetase during the synthesis of glutamine?
AMP, ADP, GDP, Ala, and glycine.
Test your knowledge of ammonia detoxification in tissues and its pathways with this quiz. Explore the main pathways of ammonia formation, temporary and final detoxification methods, hyperazotemia causes, and lab diagnostic techniques for protein metabolism.
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