Aromatase Inhibitors vs. Tamoxifen: Side Effects Quiz

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28 Questions

Which medication is associated with loss of bone mineral density that may lead to osteoporosis or bone fractures?

Anastrozole

Which side effect is common to both Aromatase Inhibitors and Tamoxifen?

Hot flashes

Which hormone replacement therapy medication is a Selective Estrogen Receptor Modulator (SERM)?

Bazedoxifene

Which group of medications is more likely to cause joint and muscle pain as a side effect?

Aromatase Inhibitors

What is a side effect specifically mentioned as rare and only in premenopausal women when taking Tamoxifen?

Bone loss

Which compound is the most potent natural estrogen?

Estradiol

What is the main reason for the increased half-life of Ethinyl Estradiol compared to other estrogens?

Carbon-carbon triple bond

Which substance is commonly used in birth control methods?

Ethinyl Estradiol

What is the main difference between Progesterone and Progestins?

Chemical composition

Which form of Progesterone is orally active and has better absorption due to faster dissolution?

Micronized Progesterone

What are the two C-21 progestins mentioned that are injected intramuscularly?

Megestrol Acetate and Medroxyprogesterone Acetate

Which contraceptive option is NOT suitable for a 30-year-old woman with a history of osteopenia and diabetes type 2, who smokes and does not have time to exercise?

Jolessa (Ethinyl estradiol/levonorgestrel)

Considering her weight and BMI, which contraceptive option might be less effective for this 30-year-old woman?

Depo-Provera IM injection (Medroxyprogesterone)

Which contraceptive option could potentially worsen acne for this 30-year-old woman?

Depo-Provera IM injection (Medroxyprogesterone)

Considering her preference for a contraceptive that does not require daily intake, which option would be the most suitable for her?

Mirena IUD (Levonorgestrel)

Considering her desire for a highly effective contraception, which option would be the best choice for this patient?

Mirena IUD (Levonorgestrel)

What should be done if a person forgets to change the Twirla patch on time?

Apply a new patch as soon as remembered and use backup contraception for 7 days.

What is the important action of C-19's in contraception?

Promoting thick mucous secretion in the cervix

What action is recommended if the Twirla patch gets detached for less than 24 hours?

Apply a new patch and consider the new day of application as the new patch change date.

Which type of C-19 progestins demonstrate little or no androgenic activity?

Those containing 'No-' or 'Nor-' in the drug name

How do C-19 progestins with anti-androgenic activity impact testosterone levels?

Tie up serum testosterone with SHBG

What is the weekly application schedule for Twirla patch during a menstrual cycle?

Once weekly application for 3 consecutive weeks, followed by 1 week patch-free per cycle.

In which areas of the body can the Twirla patch be placed?

Abdomen, buttock, or upper torso (rotate sites).

Which of the following is true regarding C-19 progestins with minimal androgenic activity?

They demonstrate overall little or no androgenic effects

What is a significant contraindication for using Twirla patch?

Women with a BMI greater than 30 kg/m2.

Which type of C-19 progestins are used in combination with ethinyl estradiol for contraception?

Those with anti-androgenic activity

How does weight affect the efficacy of Twirla patch?

Efficacy decreases as weight increases above or equal to 90 kg.

What is the role of C-19 progestins in decreasing androgenic effects?

Binding serum testosterone with SHBG

Test your knowledge on the common side effects of aromatase inhibitors (AIs) versus the side effects of Tamoxifen. Learn about the potential effects on joint and muscle pain, sex drive, bone health, and more.

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