Aromatase Inhibitors vs. Tamoxifen: Side Effects Quiz
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Questions and Answers

Which medication is associated with loss of bone mineral density that may lead to osteoporosis or bone fractures?

  • Exemestane
  • Tamoxifen
  • Letrozole
  • Anastrozole (correct)

    • Which side effect is common to both Aromatase Inhibitors and Tamoxifen?

  • Bone loss in premenopausal women
  • Vaginal discharge
  • Hot flashes (correct)
  • Loss of sex drive

    • Which hormone replacement therapy medication is a Selective Estrogen Receptor Modulator (SERM)?

  • Anastrozole
  • Bazedoxifene (correct)
  • Premarin
  • Exemestane

    • Which group of medications is more likely to cause joint and muscle pain as a side effect?

    <p>Aromatase Inhibitors (C)</p> Signup and view all the answers

    What is a side effect specifically mentioned as rare and only in premenopausal women when taking Tamoxifen?

    <p>Bone loss (A)</p> Signup and view all the answers

    Which compound is the most potent natural estrogen?

    <p>Estradiol (C)</p> Signup and view all the answers

    What is the main reason for the increased half-life of Ethinyl Estradiol compared to other estrogens?

    <p>Carbon-carbon triple bond (C)</p> Signup and view all the answers

    Which substance is commonly used in birth control methods?

    <p>Ethinyl Estradiol (B)</p> Signup and view all the answers

    What is the main difference between Progesterone and Progestins?

    <p>Chemical composition (B)</p> Signup and view all the answers

    Which form of Progesterone is orally active and has better absorption due to faster dissolution?

    <p>Micronized Progesterone (D)</p> Signup and view all the answers

    What are the two C-21 progestins mentioned that are injected intramuscularly?

    <p>Megestrol Acetate and Medroxyprogesterone Acetate (A)</p> Signup and view all the answers

    Which contraceptive option is NOT suitable for a 30-year-old woman with a history of osteopenia and diabetes type 2, who smokes and does not have time to exercise?

    <p>Jolessa (Ethinyl estradiol/levonorgestrel) (D)</p> Signup and view all the answers

    Considering her weight and BMI, which contraceptive option might be less effective for this 30-year-old woman?

    <p>Depo-Provera IM injection (Medroxyprogesterone) (D)</p> Signup and view all the answers

    Which contraceptive option could potentially worsen acne for this 30-year-old woman?

    <p>Depo-Provera IM injection (Medroxyprogesterone) (B)</p> Signup and view all the answers

    Considering her preference for a contraceptive that does not require daily intake, which option would be the most suitable for her?

    <p>Mirena IUD (Levonorgestrel) (C)</p> Signup and view all the answers

    Considering her desire for a highly effective contraception, which option would be the best choice for this patient?

    <p>Mirena IUD (Levonorgestrel) (C)</p> Signup and view all the answers

    What should be done if a person forgets to change the Twirla patch on time?

    <p>Apply a new patch as soon as remembered and use backup contraception for 7 days. (C)</p> Signup and view all the answers

    What is the important action of C-19's in contraception?

    <p>Promoting thick mucous secretion in the cervix (D)</p> Signup and view all the answers

    What action is recommended if the Twirla patch gets detached for less than 24 hours?

    <p>Apply a new patch and consider the new day of application as the new patch change date. (B)</p> Signup and view all the answers

    Which type of C-19 progestins demonstrate little or no androgenic activity?

    <p>Those containing 'No-' or 'Nor-' in the drug name (C)</p> Signup and view all the answers

    How do C-19 progestins with anti-androgenic activity impact testosterone levels?

    <p>Tie up serum testosterone with SHBG (D)</p> Signup and view all the answers

    What is the weekly application schedule for Twirla patch during a menstrual cycle?

    <p>Once weekly application for 3 consecutive weeks, followed by 1 week patch-free per cycle. (A)</p> Signup and view all the answers

    In which areas of the body can the Twirla patch be placed?

    <p>Abdomen, buttock, or upper torso (rotate sites). (B)</p> Signup and view all the answers

    Which of the following is true regarding C-19 progestins with minimal androgenic activity?

    <p>They demonstrate overall little or no androgenic effects (A)</p> Signup and view all the answers

    What is a significant contraindication for using Twirla patch?

    <p>Women with a BMI greater than 30 kg/m2. (C)</p> Signup and view all the answers

    Which type of C-19 progestins are used in combination with ethinyl estradiol for contraception?

    <p>Those with anti-androgenic activity (C)</p> Signup and view all the answers

    How does weight affect the efficacy of Twirla patch?

    <p>Efficacy decreases as weight increases above or equal to 90 kg. (D)</p> Signup and view all the answers

    What is the role of C-19 progestins in decreasing androgenic effects?

    <p>Binding serum testosterone with SHBG (B)</p> Signup and view all the answers

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