Antiviral and Antifungal Medications Effects Quiz
38 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which type of Demodex mite is found solitarily in sebaceous and Meibomian glands?

  • Demodex canis
  • Demodex brevis (correct)
  • Demodex folliculorum
  • Demodex cati
  • Which medication is NOT FDA approved for corneal ulcers but can be fortified for corneal ulcers?

  • Fluconazole
  • Amphotericin B drops
  • Voriconazole (correct)
  • Natamycin 5% drops
  • Which essential oil is known for its anti-inflammatory, antimicrobial, antifungal, and acaricidal effects against Demodex mites?

  • Peppermint oil
  • Eucalyptus oil
  • Tea tree oil (correct)
  • Lavender oil
  • What is the common ectoparasite found on human skin that is associated with blepharitis?

    <p>Demodex mites</p> Signup and view all the answers

    What is the life cycle duration of Demodex mites from egg to larval to adult stage?

    <p>14-18 days</p> Signup and view all the answers

    What do Demodex mites feed on that can cause epithelial abrasions in the eyelash follicles?

    <p>Sebum</p> Signup and view all the answers

    Which type of Demodex mite is associated with anterior blepharitis?

    <p>Demodex folliculorum</p> Signup and view all the answers

    Which drug is considered for fungal keratitis treatment after Amphotericin B drops or fortified voriconazole?

    <p>Both A and B</p> Signup and view all the answers

    Which medication is commonly used to eradicate Demodex mites and reduce ocular surface inflammation?

    <p>Tea tree oil (Cliradex)</p> Signup and view all the answers

    What do Demodex mites do in eyelash follicles that can cause collarettes?

    <p>Cause hyperkeratinization</p> Signup and view all the answers

    Which family of compounds does XDEMVY belong to?

    <p>Isoxazoline</p> Signup and view all the answers

    What is the main mechanism of action of Tea tree oil (Cliradex) against bacterial and fungal cells?

    <p>Disrupting cell wall and membrane integrity</p> Signup and view all the answers

    What is the mechanism of action of XDEMVY against Demodex mites?

    <p>Inhibits GABA-gated chloride channels</p> Signup and view all the answers

    How often should Tea tree oil (Cliradex) be used for mild to moderate symptoms of Demodex?

    <p>Once a day for 6-8 weeks</p> Signup and view all the answers

    What is the dosage regimen for XDEMVY in the treatment of Demodex blepharitis?

    <p>BID for 6 weeks</p> Signup and view all the answers

    Why is Cliradex considered a cosmetic product that does not require FDA approval?

    <p>It is used for Demodex and severe ocular irritation</p> Signup and view all the answers

    Which adverse drug reaction (ADR) is commonly associated with XDEMVY use?

    <p>Stinging and burning</p> Signup and view all the answers

    Which of the following statements about using Tea tree oil (Cliradex) is FALSE?

    <p>It should be applied once a week for blepharitis</p> Signup and view all the answers

    What effect does inhibiting GABA channels with XDEMVY have on mammals?

    <p>No effect on mammals</p> Signup and view all the answers

    What is the primary benefit of using Natamycin drops over Amphotericin B drops in fungal keratitis treatment?

    <p>Broader spectrum of antifungal activity</p> Signup and view all the answers

    In the context of fungal keratitis treatment, when is the optimal window to use povidone-iodine and ATs to reduce symptoms like redness and tearing?

    <p>Within 4 days</p> Signup and view all the answers

    What type of microorganisms do antifungal drugs primarily target?

    <p>Both molds and yeasts</p> Signup and view all the answers

    Which type of infection is commonly associated with candida, a yeast fungus?

    <p>Oral cavity infections</p> Signup and view all the answers

    How many species of microorganisms belong to the group that includes fungi, as mentioned in the text?

    <p>100,000 species</p> Signup and view all the answers

    Which type of drops are typically used for fungal keratitis treatment against yeast and molds?

    <p>Natamycin drops</p> Signup and view all the answers

    Which antifungal drug is specifically mentioned as a topical ophthalmic treatment for fungal keratitis?

    <p>Natamycin</p> Signup and view all the answers

    What is the mechanism of action of polyenes like Amphotericin B in treating fungal infections?

    <p>Binding to ergosterol in the fungal cell membrane, increasing membrane permeability</p> Signup and view all the answers

    Which systemic antifungal drug is NOT mentioned in the text as a treatment option for fungal keratitis?

    <p>Flucytosine</p> Signup and view all the answers

    What is the clinical use of Amphotericin B in relation to ophthalmic conditions?

    <p>Fungal keratitis and corneal ulcers treatment</p> Signup and view all the answers

    In the context of the text, what is the significance of topical ophthalmic drops being 'fortified'?

    <p>Enhanced bioavailability of the drug</p> Signup and view all the answers

    What is the main indication for Zirgan 0.15% (Ganciclovir Ophthalmic Gel) according to the text?

    <p>Dendritic ulcers in herpetic keratitis</p> Signup and view all the answers

    What is the mechanism of action of Ganciclovir in Zirgan 0.15%?

    <p>Inhibition of DNA replication of HSV by disrupting viral and cellular kinases</p> Signup and view all the answers

    What is a common adverse reaction associated with Zirgan 0.15% use, as mentioned in the text?

    <p>Blurred vision</p> Signup and view all the answers

    How frequently should Zirgan 0.15% (Ganciclovir Ophthalmic Gel) be initially used according to the text's dosing instructions?

    <p>Five times a day</p> Signup and view all the answers

    Which drug is Zirgan analogous to, as mentioned in the text?

    <p>Acyclovir</p> Signup and view all the answers

    What is the main adverse effect that might be experienced by patients using Zirgan 0.15%?

    <p>Hyperemia</p> Signup and view all the answers

    In what condition should Zirgan be very frequently used, as suggested in the text?

    <p><strong>Viral</strong> keratitis</p> Signup and view all the answers

    How long should Zirgan 0.15% (Ganciclovir Ophthalmic Gel) be tapered to after initially using it every 3 hours for 7 days?

    <p><strong>Once</strong> a day</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser