Antithyroid Medications Quiz

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What is the objective of using antithyroid medications?

To enhance the coupling of iodotyrosines

To increase iodine utilization

To promote thyroid hormone synthesis

To inhibit thyroid hormone synthesis or hormone release (correct)

How do antithyroid agents affect the synthesis of thyroid hormones?

By blocking the utilization of iodine and interfering with the iodination of tyrosine (correct)

By increasing the coupling of iodotyrosines

By promoting the utilization of iodine and enhancing the iodination of tyrosine

By inhibiting the release of iodine

Which medications are commonly used as antithyroid drugs in the United States?

Methimazole or propylthiouracil (correct)

Thyroid-stimulating hormone (TSH)

Levothyroxine or liothyronine

Iodine or iodide

What baseline blood tests are performed prior to initiating therapy with antithyroid drugs?

Complete blood count and liver profile Signup and view all the answers

How is the therapeutic dose of antithyroid medications determined?

On the basis of clinical criteria, including changes in pulse rate, pulse pressure, body weight, size of the goiter, and results of laboratory studies Signup and view all the answers

When should the patient be instructed to take the antithyroid medication?

In the morning on an empty stomach 30 minutes before eating Signup and view all the answers

What is the purpose of instructing the patient to take the medication on an empty stomach?

To avoid decrease in absorption associated with some foods Signup and view all the answers

What is the recommended antithyroid medication during the first trimester of pregnancy?

Propylthiouracil Signup and view all the answers

What should the patient do if any sign of infection, especially pharyngitis and fever, occurs while taking antithyroid medication?

Stop the medication, notify the primary provider immediately, and undergo hematologic studies Signup and view all the answers

What is the consequence of discontinuing antithyroid medications before therapy is complete?

Relapse within 6 months Signup and view all the answers

What is the risk associated with propylthiouracil use after the first trimester of pregnancy?

Hepatotoxicity Signup and view all the answers

What is the recommended action if fever, rash, urticaria, or agranulocytosis develops while taking antithyroid medication?

Stop the medication and consult the primary provider Signup and view all the answers

How long may it take for symptom relief to occur after starting antithyroid medication?

Several weeks Signup and view all the answers

What is the outcome of toxic complications associated with antithyroid medications?

Relatively uncommon Signup and view all the answers

When should methimazole be used during pregnancy?

Throughout the entire pregnancy Signup and view all the answers

What is the recommended antithyroid medication during the first trimester of pregnancy?

Propylthiouracil Signup and view all the answers

What may develop if a patient experiences medication sensitization, fever, rash, or urticaria?

Agranulocytosis and thrombocytopenia Signup and view all the answers

What is the consequence of discontinuing antithyroid medications before therapy is complete?

Relapse within 6 months Signup and view all the answers

What should a patient do if they experience any sign of infection while on antithyroid medication?

Stop the medication and notify the primary provider immediately Signup and view all the answers

What is the risk associated with propylthiouracil during pregnancy?

Hepatotoxicity Signup and view all the answers

When is methimazole recommended during pregnancy?

After the first trimester and when breast-feeding Signup and view all the answers

What is the effect of antithyroid medications on previously formed thyroid hormones?

They do not interfere with the release or activity Signup and view all the answers

What is the importance of periodic follow-up for patients on antithyroid medications?

To monitor for toxic complications and medication sensitization Signup and view all the answers

What is the mechanism of action of antithyroid medications?

Inhibiting the utilization of iodine and interfering with the synthesis of thyroid hormones Signup and view all the answers

What is the recommended timing for taking antithyroid medication?

In the morning on an empty stomach 30 minutes before eating Signup and view all the answers

What is the objective of using antithyroid medications?

To inhibit one or more stages in thyroid hormone synthesis or hormone release Signup and view all the answers

What baseline blood tests are performed prior to initiating therapy with antithyroid drugs?

Complete blood count and liver profile Signup and view all the answers

What is the consequence of discontinuing antithyroid medications before therapy is complete?

Rebound hyperthyroidism Signup and view all the answers

What is the risk associated with propylthiouracil use after the first trimester of pregnancy?

Risk of hepatotoxicity Signup and view all the answers

What may develop if a patient experiences medication sensitization, fever, rash, or urticaria while taking antithyroid medication?

Agranulocytosis and thrombocytopenia Signup and view all the answers

When should methimazole be used during pregnancy?

After the first trimester Signup and view all the answers

What is the consequence of discontinuing antithyroid medications before therapy is complete?

Relapse within 6 months Signup and view all the answers

What is the effect of antithyroid medications on previously formed thyroid hormones?

Do not interfere with release or activity Signup and view all the answers

What is the risk of hepatotoxicity associated with propylthiouracil use during pregnancy?

It is relatively uncommon Signup and view all the answers

What is the consequence of discontinuing antithyroid medications before therapy is complete?

Relapse within 6 months Signup and view all the answers

What is the recommended antithyroid medication during the first trimester of pregnancy?

Propylthiouracil Signup and view all the answers

What should a patient do if any sign of infection, especially pharyngitis and fever, occurs while taking antithyroid medication?

Stop the medication and notify the primary provider immediately Signup and view all the answers

What is the outcome of toxic complications associated with antithyroid medications?

They are rare and unlikely Signup and view all the answers

Antithyroid Medications Quiz

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Questions and Answers

What is the objective of using antithyroid medications?

How do antithyroid agents affect the synthesis of thyroid hormones?

Which medications are commonly used as antithyroid drugs in the United States?

What baseline blood tests are performed prior to initiating therapy with antithyroid drugs?

How is the therapeutic dose of antithyroid medications determined?

When should the patient be instructed to take the antithyroid medication?

What is the purpose of instructing the patient to take the medication on an empty stomach?

What is the recommended antithyroid medication during the first trimester of pregnancy?

What should the patient do if any sign of infection, especially pharyngitis and fever, occurs while taking antithyroid medication?

What is the consequence of discontinuing antithyroid medications before therapy is complete?

What is the risk associated with propylthiouracil use after the first trimester of pregnancy?

What is the recommended action if fever, rash, urticaria, or agranulocytosis develops while taking antithyroid medication?

How long may it take for symptom relief to occur after starting antithyroid medication?

What is the outcome of toxic complications associated with antithyroid medications?

When should methimazole be used during pregnancy?

What is the recommended antithyroid medication during the first trimester of pregnancy?

What may develop if a patient experiences medication sensitization, fever, rash, or urticaria?

What is the consequence of discontinuing antithyroid medications before therapy is complete?

What should a patient do if they experience any sign of infection while on antithyroid medication?

What is the risk associated with propylthiouracil during pregnancy?

When is methimazole recommended during pregnancy?

What is the effect of antithyroid medications on previously formed thyroid hormones?

What is the importance of periodic follow-up for patients on antithyroid medications?

What is the mechanism of action of antithyroid medications?

What is the recommended timing for taking antithyroid medication?

What is the objective of using antithyroid medications?

What baseline blood tests are performed prior to initiating therapy with antithyroid drugs?

What is the consequence of discontinuing antithyroid medications before therapy is complete?

What is the risk associated with propylthiouracil use after the first trimester of pregnancy?

What may develop if a patient experiences medication sensitization, fever, rash, or urticaria while taking antithyroid medication?

When should methimazole be used during pregnancy?

What is the consequence of discontinuing antithyroid medications before therapy is complete?

What is the effect of antithyroid medications on previously formed thyroid hormones?

What is the risk of hepatotoxicity associated with propylthiouracil use during pregnancy?

What is the consequence of discontinuing antithyroid medications before therapy is complete?

What is the recommended antithyroid medication during the first trimester of pregnancy?

What should a patient do if any sign of infection, especially pharyngitis and fever, occurs while taking antithyroid medication?

What is the outcome of toxic complications associated with antithyroid medications?

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