Podcast
Questions and Answers
Which of the following is a contraindication for radioactive iodine therapy?
Which of the following is a contraindication for radioactive iodine therapy?
- Pregnancy (correct)
- Allergy to iodine
- Breastfeeding
- History of thyroid surgery
What is the goal of radioactive iodine therapy (131I)?
What is the goal of radioactive iodine therapy (131I)?
- To reduce thyroid hormone production by 50%
- To provide symptomatic relief without affecting thyroid function
- To prevent the development of thyroid nodules
- To eliminate the hyperthyroid state with the administration of sufficient radiation in a single dose (correct)
Why is radioactive iodine considered the treatment of choice for hyperthyroidism?
Why is radioactive iodine considered the treatment of choice for hyperthyroidism?
- It is less expensive than other treatment options
- It has no side effects
- It can be used during pregnancy
- A single dose is effective in treating 80% to 90% of cases (correct)
What is the recommended timing for taking antithyroid medications?
What is the recommended timing for taking antithyroid medications?
What is the principal test used for monitoring patients early after radioactive iodine treatment?
What is the principal test used for monitoring patients early after radioactive iodine treatment?
Which medication is recommended during the first trimester of pregnancy due to teratogenic effects of the other?
Which medication is recommended during the first trimester of pregnancy due to teratogenic effects of the other?
What is the plasma half-life of propylthiouracil?
What is the plasma half-life of propylthiouracil?
In which population is radioactive iodine preferred over propylthiouracil?
In which population is radioactive iodine preferred over propylthiouracil?
What is the only contraindication to propylthiouracil?
What is the only contraindication to propylthiouracil?
Which drug is similar to propylthiouracil and carries a risk of fetal abnormalities?
Which drug is similar to propylthiouracil and carries a risk of fetal abnormalities?
What is the radioactive isotope used to treat hyperthyroidism and thyroid cancer?
What is the radioactive isotope used to treat hyperthyroidism and thyroid cancer?
Which drug is recommended for all patients with symptomatic hyperthyroidism to control symptoms such as tachycardia and palpitations?
Which drug is recommended for all patients with symptomatic hyperthyroidism to control symptoms such as tachycardia and palpitations?
What should patients avoid after therapy with sodium iodide 131I?
What should patients avoid after therapy with sodium iodide 131I?
What is used in short-term treatment of hyperthyroidism but should not be followed by certain antithyroid drugs?
What is used in short-term treatment of hyperthyroidism but should not be followed by certain antithyroid drugs?
What should patients receive instructions about in relation to antithyroid drugs and acute liver failure?
What should patients receive instructions about in relation to antithyroid drugs and acute liver failure?
Patients should avoid \underline{seafood} or iodized salt
Patients should avoid \underline{seafood} or iodized salt
Strong iodine solution and saturated solution of potassium iodide are iodine preparations used in short-term treatment of hyperthyroidism, but should not be followed by certain ______ drugs
Strong iodine solution and saturated solution of potassium iodide are iodine preparations used in short-term treatment of hyperthyroidism, but should not be followed by certain ______ drugs
Methimazole is similar to propylthiouracil and carries a risk of \underline{fetal} ______, requiring a pregnancy test before use during the first trimester
Methimazole is similar to propylthiouracil and carries a risk of \underline{fetal} ______, requiring a pregnancy test before use during the first trimester
Sodium iodide 131I is a radioactive isotope used to treat hyperthyroidism and thyroid cancer, but can lead to \underline{______} and requires lifelong hormone replacement therapy
Sodium iodide 131I is a radioactive isotope used to treat hyperthyroidism and thyroid cancer, but can lead to \underline{______} and requires lifelong hormone replacement therapy
The therapeutic benefits of sodium iodide 131I may not be apparent for 3 months or longer, and patients should avoid \underline{______} or coughing freely for 24 hours after therapy
The therapeutic benefits of sodium iodide 131I may not be apparent for 3 months or longer, and patients should avoid \underline{______} or coughing freely for 24 hours after therapy
Propranolol is particularly useful in older adults with resting heart rates greater than 90 beats/min or a history of \underline{______} conditions
Propranolol is particularly useful in older adults with resting heart rates greater than 90 beats/min or a history of \underline{______} conditions
Patients should receive instructions about signs and symptoms of acute \underline{______} failure and seek immediate medical treatment if these symptoms occur
Patients should receive instructions about signs and symptoms of acute \underline{______} failure and seek immediate medical treatment if these symptoms occur
Anti______ drugs are used to treat an overactive ______ gland by decreasing the production of \underline{______} hormone
Anti______ drugs are used to treat an overactive ______ gland by decreasing the production of \underline{______} hormone
Once patients become euthyroid and definitive treatment has controlled hyperthyroid symptoms, propranolol should be \underline{______} and discontinued
Once patients become euthyroid and definitive treatment has controlled hyperthyroid symptoms, propranolol should be \underline{______} and discontinued
Propranolol is a beta-adrenergic–blocking agent recommended for all patients with symptomatic hyperthyroidism to control symptoms such as \underline{______}, palpitations, excessive sweating, and nervousness
Propranolol is a beta-adrenergic–blocking agent recommended for all patients with symptomatic hyperthyroidism to control symptoms such as \underline{______}, palpitations, excessive sweating, and nervousness
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Study Notes
Antithyroid Drug Patient Teaching and Other Drugs
- Antithyroid drugs are used to treat an overactive thyroid gland by decreasing the production of thyroid hormone.
- Patients should receive instructions about signs and symptoms of acute liver failure and seek immediate medical treatment if these symptoms occur.
- Patient teaching guidelines for propylthiouracil include regular thyroid and liver function tests, avoiding seafood or iodized salt, and taking the drug at regular intervals.
- Patients should report adverse effects to the prescriber and consult a healthcare provider before taking over-the-counter drugs.
- Methimazole is similar to propylthiouracil and carries a risk of fetal abnormalities, requiring a pregnancy test before use during the first trimester.
- Strong iodine solution and saturated solution of potassium iodide are iodine preparations used in short-term treatment of hyperthyroidism, but should not be followed by certain antithyroid drugs.
- Sodium iodide 131I is a radioactive isotope used to treat hyperthyroidism and thyroid cancer, but can lead to hypothyroidism and requires lifelong hormone replacement therapy.
- The therapeutic benefits of sodium iodide 131I may not be apparent for 3 months or longer, and patients should avoid expectorating or coughing freely for 24 hours after therapy.
- Propranolol is a beta-adrenergic–blocking agent recommended for all patients with symptomatic hyperthyroidism to control symptoms such as tachycardia, palpitations, excessive sweating, and nervousness.
- Propranolol is particularly useful in older adults with resting heart rates greater than 90 beats/min or a history of cardiovascular conditions.
- Propranolol is used to control symptoms during the delayed response to other hyperthyroidism treatments, before thyroidectomy, and in treating thyrotoxic crisis.
- Once patients become euthyroid and definitive treatment has controlled hyperthyroid symptoms, propranolol should be tapered and discontinued.
Antithyroid Drug Patient Teaching and Other Drugs
- Antithyroid drugs are used to treat an overactive thyroid gland by decreasing the production of thyroid hormone.
- Patients should receive instructions about signs and symptoms of acute liver failure and seek immediate medical treatment if these symptoms occur.
- Patient teaching guidelines for propylthiouracil include regular thyroid and liver function tests, avoiding seafood or iodized salt, and taking the drug at regular intervals.
- Patients should report adverse effects to the prescriber and consult a healthcare provider before taking over-the-counter drugs.
- Methimazole is similar to propylthiouracil and carries a risk of fetal abnormalities, requiring a pregnancy test before use during the first trimester.
- Strong iodine solution and saturated solution of potassium iodide are iodine preparations used in short-term treatment of hyperthyroidism, but should not be followed by certain antithyroid drugs.
- Sodium iodide 131I is a radioactive isotope used to treat hyperthyroidism and thyroid cancer, but can lead to hypothyroidism and requires lifelong hormone replacement therapy.
- The therapeutic benefits of sodium iodide 131I may not be apparent for 3 months or longer, and patients should avoid expectorating or coughing freely for 24 hours after therapy.
- Propranolol is a beta-adrenergic–blocking agent recommended for all patients with symptomatic hyperthyroidism to control symptoms such as tachycardia, palpitations, excessive sweating, and nervousness.
- Propranolol is particularly useful in older adults with resting heart rates greater than 90 beats/min or a history of cardiovascular conditions.
- Propranolol is used to control symptoms during the delayed response to other hyperthyroidism treatments, before thyroidectomy, and in treating thyrotoxic crisis.
- Once patients become euthyroid and definitive treatment has controlled hyperthyroid symptoms, propranolol should be tapered and discontinued.
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