Podcast
Questions and Answers
What are the effects of blocking D2R in the tuberoinfundibular pathway?
What are the effects of blocking D2R in the tuberoinfundibular pathway?
Increased prolactin secretion and gynaecomastia
How does blocking D2R in the nigrostriatal pathway lead to extrapyramidal side-effects?
How does blocking D2R in the nigrostriatal pathway lead to extrapyramidal side-effects?
It leads to extrapyramidal side-effects such as parkinsonism and tardive dyskinesia.
In which pathway does hypofunction of the dopaminergic system underlie negative symptoms?
In which pathway does hypofunction of the dopaminergic system underlie negative symptoms?
Mesocortical pathway
What evidence supports the dopamine hypothesis of schizophrenia?
What evidence supports the dopamine hypothesis of schizophrenia?
What are the three main dopamine pathways in the brain?
What are the three main dopamine pathways in the brain?
What side effects can be caused by the blockade of dopamine D2 receptors by typical antipsychotic drugs, and why do they occur?
What side effects can be caused by the blockade of dopamine D2 receptors by typical antipsychotic drugs, and why do they occur?
What are the lecture outcomes related to schizophrenia symptoms and pathophysiology?
What are the lecture outcomes related to schizophrenia symptoms and pathophysiology?
What are the lecture outcomes related to current antipsychotic drugs?
What are the lecture outcomes related to current antipsychotic drugs?
What is the incidence of schizophrenia in the general population?
What is the incidence of schizophrenia in the general population?
What is the percentage of incidence for schizophrenia if there is a family history?
What is the percentage of incidence for schizophrenia if there is a family history?
