Antipsychotic Medications: Mechanism of Action and Classification

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Questions and Answers

What is the primary mechanism of action of typical antipsychotics in the brain?

  • Inhibition of GABAergic neurotransmission
  • Blockage of dopamine D2 receptors in the mesolimbic pathway (correct)
  • Blockage of serotonin 5-HT2A receptors
  • Stimulation of dopamine D1 receptors in the prefrontal cortex

Which of the following antipsychotics is classified as a typical antipsychotic?

  • Chlorpromazine (correct)
  • Aripiprazole
  • Quetiapine
  • Risperidone

What is a potential side effect of typical antipsychotics?

  • Increased libido
  • Weight loss
  • Extrapyramidal symptoms such as dystonia (correct)
  • Improved cognitive function

What is a characteristic of atypical antipsychotics compared to typical antipsychotics?

<p>Broader receptor profile (A)</p> Signup and view all the answers

Which of the following is an example of an atypical antipsychotic?

<p>Olanzapine (D)</p> Signup and view all the answers

What is a characteristic of aripiprazole as an atypical antipsychotic?

<p>It acts as a partial agonist at dopamine D2 receptors (C)</p> Signup and view all the answers

What is a potential side effect of atypical antipsychotics?

<p>Weight gain and increased risk of diabetes (C)</p> Signup and view all the answers

What is a factor to consider when choosing an antipsychotic and dosing regimen?

<p>The patient's age and medical comorbidities (C)</p> Signup and view all the answers

What is the mechanism of aripiprazole's action in treating psychotic symptoms?

<p>It stabilizes dopamine activity (B)</p> Signup and view all the answers

What is the benefit of atypical antipsychotics compared to typical antipsychotics?

<p>They have a lower risk of extrapyramidal side effects (B)</p> Signup and view all the answers

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