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Antipsychotic Medications: Mechanism of Action and Classification

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Antipsychotic Medications: Mechanism of Action and Classification

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Questions and Answers

What is the primary mechanism of action of typical antipsychotics in the brain?

Inhibition of GABAergic neurotransmission

Blockage of dopamine D2 receptors in the mesolimbic pathway (correct)

Blockage of serotonin 5-HT2A receptors

Stimulation of dopamine D1 receptors in the prefrontal cortex

Which of the following antipsychotics is classified as a typical antipsychotic?

Chlorpromazine (correct)

Aripiprazole

Quetiapine

Risperidone

What is a potential side effect of typical antipsychotics?

Increased libido

Weight loss

Extrapyramidal symptoms such as dystonia (correct)

Improved cognitive function

What is a characteristic of atypical antipsychotics compared to typical antipsychotics?

Broader receptor profile Signup and view all the answers

Which of the following is an example of an atypical antipsychotic?

Olanzapine Signup and view all the answers

What is a characteristic of aripiprazole as an atypical antipsychotic?

It acts as a partial agonist at dopamine D2 receptors Signup and view all the answers

What is a potential side effect of atypical antipsychotics?

Weight gain and increased risk of diabetes Signup and view all the answers

What is a factor to consider when choosing an antipsychotic and dosing regimen?

The patient's age and medical comorbidities Signup and view all the answers

What is the mechanism of aripiprazole's action in treating psychotic symptoms?

It stabilizes dopamine activity Signup and view all the answers

What is the benefit of atypical antipsychotics compared to typical antipsychotics?

They have a lower risk of extrapyramidal side effects Signup and view all the answers