Psychopharmacology: Antipsychotics and Mood Disorders

Phenothiazines exhibit anti-H2 activity.

Droperidol is used to produce neuroleptanesthesia.

Tardive dyskinesia is a rare side effect of antipsychotic drugs.

Molindone is an antipsychotic that can cause weight gain.

Thioridazine can cause retinal deposits leading to blindness.

Clozapine is a first-generation antipsychotic.

The serotonin hypothesis suggests that abnormal transmission in 5-HT1A and 5-HT1C leads to hallucinatory effects in schizophrenia.

Dopamine hypothesis is related to the negative symptoms of schizophrenia.

The glutamate hypothesis suggests that hyperactivity of NMDA receptor leads to cognitive impairment and psychosis.

Avolition/Apathy is a positive symptom of schizophrenia.

Affective flattening is a symptom of schizophrenia characterized by excessive emotional expression.

Delusions are a type of negative symptom of schizophrenia.

Levetiracetam is metabolized extensively in the liver.

Topiramate is used as an adjunct therapy for myoclonic seizures only.

Levetiracetam binds to synaptic vesicle protein 2B (SV2B) which is responsible for modulating NT release (glutamate).

Levetiracetam has significant drug interactions.

Topiramate is primarily excreted in the feces.

Levetiracetam is used as a monotherapy for generalized tonic-clonic seizures.