Podcast
Questions and Answers
What are the two major categories of antipsychotic drugs?
What are the two major categories of antipsychotic drugs?
- Typical and atypical (correct)
- Dopaminergic and non-dopaminergic
- Neuroleptic and major tranquilizers
- Conventional and atypical
What is the theory that overstimulation of dopamine (D) receptors is at the heart of schizophrenia called?
What is the theory that overstimulation of dopamine (D) receptors is at the heart of schizophrenia called?
- The serotonin hypothesis
- The GABA hypothesis
- The glutamate hypothesis
- The dopamine hypothesis (correct)
Which class of antipsychotic drugs includes the drug chlorpromazine (Thorazine)?
Which class of antipsychotic drugs includes the drug chlorpromazine (Thorazine)?
- Benzisoxazoles
- Quinolinones
- Thienobenzodiazepines
- Phenothiazines (correct)
What is the primary effect of typical antipsychotics in reducing the positive symptoms of schizophrenia?
What is the primary effect of typical antipsychotics in reducing the positive symptoms of schizophrenia?
Which class of antipsychotics includes the drug asenapine?
Which class of antipsychotics includes the drug asenapine?
What was the first antipsychotic drug used to treat psychosis, according to the passage?
What was the first antipsychotic drug used to treat psychosis, according to the passage?
Which side effect of typical antipsychotics is characterized by involuntary, painful movements?
Which side effect of typical antipsychotics is characterized by involuntary, painful movements?
What is the term used to describe the side effect characterized by restlessness?
What is the term used to describe the side effect characterized by restlessness?
Which drug interaction poses the most serious risk of CNS depression when combined with antipsychotics?
Which drug interaction poses the most serious risk of CNS depression when combined with antipsychotics?
Among the listed side effects, which one may be irreversible if it occurs?
Among the listed side effects, which one may be irreversible if it occurs?
What is a common symptom of pseudoparkinsonism associated with typical antipsychotics?
What is a common symptom of pseudoparkinsonism associated with typical antipsychotics?
Which side effect of typical antipsychotics is related to difficulty speaking and swallowing?
Which side effect of typical antipsychotics is related to difficulty speaking and swallowing?
Which of the following is NOT a characteristic of the newer atypical antipsychotic agents?
Which of the following is NOT a characteristic of the newer atypical antipsychotic agents?
According to the passage, what should practitioners do after 3 months of prescribing an atypical antipsychotic?
According to the passage, what should practitioners do after 3 months of prescribing an atypical antipsychotic?
What is the primary mechanism of action by which atypical antipsychotics reduce the negative symptoms of schizophrenia?
What is the primary mechanism of action by which atypical antipsychotics reduce the negative symptoms of schizophrenia?
Which of the following is a true statement about the pharmacokinetics of atypical antipsychotics?
Which of the following is a true statement about the pharmacokinetics of atypical antipsychotics?
Which of the following is a contraindication for the use of atypical antipsychotics?
Which of the following is a contraindication for the use of atypical antipsychotics?
Which of the following adverse effects is LEAST likely to occur with the use of atypical antipsychotics compared to typical antipsychotics?
Which of the following adverse effects is LEAST likely to occur with the use of atypical antipsychotics compared to typical antipsychotics?
What is the primary reason why clozapine is reserved for the treatment of severe schizophrenia refractory to other antipsychotics?
What is the primary reason why clozapine is reserved for the treatment of severe schizophrenia refractory to other antipsychotics?
Which of the following atypical antipsychotics is associated with the highest incidence of weight gain and sedation?
Which of the following atypical antipsychotics is associated with the highest incidence of weight gain and sedation?
What is the primary reason why atypical antipsychotics should be prescribed cautiously in the presence of hepatic or renal disease?
What is the primary reason why atypical antipsychotics should be prescribed cautiously in the presence of hepatic or renal disease?
Which of the following is a true statement about the onset of action and time to steady state for atypical antipsychotics?
Which of the following is a true statement about the onset of action and time to steady state for atypical antipsychotics?
According to the current hypothesis, what is thought to contribute to the positive symptoms of schizophrenia?
According to the current hypothesis, what is thought to contribute to the positive symptoms of schizophrenia?
What are typical antipsychotics less effective in treating?
What are typical antipsychotics less effective in treating?
At approximately what percentage of D2 receptor occupancy do extrapyramidal symptoms become more prominent?
At approximately what percentage of D2 receptor occupancy do extrapyramidal symptoms become more prominent?
Which of the following is a typical antipsychotic from the phenothiazine group?
Which of the following is a typical antipsychotic from the phenothiazine group?
What is a life-threatening adverse reaction associated with typical antipsychotics?
What is a life-threatening adverse reaction associated with typical antipsychotics?
Which of the following statements about the pharmacokinetics of typical antipsychotics is true?
Which of the following statements about the pharmacokinetics of typical antipsychotics is true?
What percentage of D2 receptor blockade is associated with clinical effectiveness of typical antipsychotics?
What percentage of D2 receptor blockade is associated with clinical effectiveness of typical antipsychotics?
Which of the following is a precaution or contraindication for the use of typical antipsychotics?
Which of the following is a precaution or contraindication for the use of typical antipsychotics?
Which of the following statements about the FDA Black Box Warning for typical antipsychotics is true?
Which of the following statements about the FDA Black Box Warning for typical antipsychotics is true?
Which of the following statements about high-potency typical antipsychotics is true?
Which of the following statements about high-potency typical antipsychotics is true?
Which atypical antipsychotic drug is known to address both the positive and negative symptoms of schizophrenia?
Which atypical antipsychotic drug is known to address both the positive and negative symptoms of schizophrenia?
What is the maximum daily dose recommended for Thioridazine in adults with psychosis?
What is the maximum daily dose recommended for Thioridazine in adults with psychosis?
In which age group should the Abnormal Involuntary Movement Scale (AIMS) be rated more frequently according to the instructions?
In which age group should the Abnormal Involuntary Movement Scale (AIMS) be rated more frequently according to the instructions?
What is the usual optimal dose range for Thiothixene in adults with severe psychosis?
What is the usual optimal dose range for Thiothixene in adults with severe psychosis?
Which antipsychotic drug is specifically used for the treatment of motor and phonic tics in patients with Tourette’s syndrome?
Which antipsychotic drug is specifically used for the treatment of motor and phonic tics in patients with Tourette’s syndrome?
What is the appropriate initial dose of Loxapine for adults and children over 12 years with acute severe agitation?
What is the appropriate initial dose of Loxapine for adults and children over 12 years with acute severe agitation?
Which of the following antipsychotic drugs should undergo genotyping for CYP2D6 if doses exceed 4 mg/day?
Which of the following antipsychotic drugs should undergo genotyping for CYP2D6 if doses exceed 4 mg/day?
What is the maximum recommended dose of Pimozide per day in children and adults?
What is the maximum recommended dose of Pimozide per day in children and adults?
Which atypical antipsychotic drug could be most beneficial for patients concerned about cognitive functioning interference?
Which atypical antipsychotic drug could be most beneficial for patients concerned about cognitive functioning interference?
Which of the following antipsychotics has tablets available in 10, 12, 25, 50, 100, 120, and 200 mg doses?
Which of the following antipsychotics has tablets available in 10, 12, 25, 50, 100, 120, and 200 mg doses?
According to the information provided, what should be done when lurasidone is coadministered with strong CYP3A4 inhibitors like ketoconazole or clarithromycin?
According to the information provided, what should be done when lurasidone is coadministered with strong CYP3A4 inhibitors like ketoconazole or clarithromycin?
What is recommended when iloperidone is coadministered with CYP2D6 inhibitors like fluoxetine or paroxetine?
What is recommended when iloperidone is coadministered with CYP2D6 inhibitors like fluoxetine or paroxetine?
How should the asenapine dose be adjusted when coadministered with fluvoxamine?
How should the asenapine dose be adjusted when coadministered with fluvoxamine?
What is recommended when aripiprazole is coadministered with carbamazepine or other CYP3A4 inducers?
What is recommended when aripiprazole is coadministered with carbamazepine or other CYP3A4 inducers?
How should the aripiprazole dose be adjusted when coadministered with quinidine or other CYP2D6 inhibitors like fluoxetine or paroxetine?
How should the aripiprazole dose be adjusted when coadministered with quinidine or other CYP2D6 inhibitors like fluoxetine or paroxetine?
According to the information provided, what should be done when lurasidone is coadministered with moderate CYP3A4 inducers like St. John's wort or phenytoin?
According to the information provided, what should be done when lurasidone is coadministered with moderate CYP3A4 inducers like St. John's wort or phenytoin?
What is the potential effect of combining atypical antipsychotics with antihypertensives?
What is the potential effect of combining atypical antipsychotics with antihypertensives?
Which drug interaction may lead to increased atypical antipsychotic levels due to its effect as a potent 1A2 inhibitor?
Which drug interaction may lead to increased atypical antipsychotic levels due to its effect as a potent 1A2 inhibitor?
What is a possible implication of combining clozapine with anticholinergics?
What is a possible implication of combining clozapine with anticholinergics?
How does smoking affect the metabolism of antipsychotics?
How does smoking affect the metabolism of antipsychotics?
What may happen when olanzapine and quetiapine are used concurrently with rifampin or SSRIs?
What may happen when olanzapine and quetiapine are used concurrently with rifampin or SSRIs?
What is the implication of combining carbamazepine with olanzapine?
What is the implication of combining carbamazepine with olanzapine?
Which drug interaction should prompt ECG monitoring due to potentially life-threatening cardiac changes?
Which drug interaction should prompt ECG monitoring due to potentially life-threatening cardiac changes?
What potential effect does carbamazepine have when combined with clozapine?
What potential effect does carbamazepine have when combined with clozapine?
Which of the following adverse effects is associated with the use of olanzapine?
Which of the following adverse effects is associated with the use of olanzapine?
According to the passage, which of the following statements about clozapine is correct?
According to the passage, which of the following statements about clozapine is correct?
Which of the following adverse effects is associated with the use of ziprasidone?
Which of the following adverse effects is associated with the use of ziprasidone?
Which of the following statements about aripiprazole is correct?
Which of the following statements about aripiprazole is correct?
Which of the following adverse effects is associated with the use of brexpiprazole or cariprazine in older adult patients with dementia-related psychosis?
Which of the following adverse effects is associated with the use of brexpiprazole or cariprazine in older adult patients with dementia-related psychosis?
According to the passage, which of the following adverse effects is associated with the use of iloperidone?
According to the passage, which of the following adverse effects is associated with the use of iloperidone?
Which of the following statements about paliperidone is correct, according to the passage?
Which of the following statements about paliperidone is correct, according to the passage?
According to the passage, which of the following adverse effects is associated with the use of pimavanserin?
According to the passage, which of the following adverse effects is associated with the use of pimavanserin?
Which of the following adverse effects is associated with the use of risperidone, according to the passage?
Which of the following adverse effects is associated with the use of risperidone, according to the passage?
According to the passage, which of the following statements about quetiapine is correct?
According to the passage, which of the following statements about quetiapine is correct?
What is the primary reason for monitoring patients taking typical antipsychotics with the Abnormal Involuntary Movement Scale (AIMS)?
What is the primary reason for monitoring patients taking typical antipsychotics with the Abnormal Involuntary Movement Scale (AIMS)?
Which of the following is NOT a potential consequence of chronic prolactin elevation caused by typical antipsychotics?
Which of the following is NOT a potential consequence of chronic prolactin elevation caused by typical antipsychotics?
Which of the following is the BEST advice to give a patient taking typical antipsychotics?
Which of the following is the BEST advice to give a patient taking typical antipsychotics?
What is the MAXIMUM recommended daily oral dose for an adult of the typical antipsychotic chlorpromazine (Thorazine)?
What is the MAXIMUM recommended daily oral dose for an adult of the typical antipsychotic chlorpromazine (Thorazine)?
What is the MOST common cause of increased symptoms and hospitalization in patients taking typical antipsychotics?
What is the MOST common cause of increased symptoms and hospitalization in patients taking typical antipsychotics?
Which of the following is a recommended strategy to address constipation, a potential anticholinergic effect of typical antipsychotics?
Which of the following is a recommended strategy to address constipation, a potential anticholinergic effect of typical antipsychotics?
What is the MAIN purpose of using the depot or decanoate form of a typical antipsychotic medication?
What is the MAIN purpose of using the depot or decanoate form of a typical antipsychotic medication?
Which of the following is a potential side effect of the typical antipsychotic fluphenazine (Prolixin) that may require dose adjustment?
Which of the following is a potential side effect of the typical antipsychotic fluphenazine (Prolixin) that may require dose adjustment?
Which of the following is the MOST appropriate advice to give a patient taking a typical antipsychotic medication?
Which of the following is the MOST appropriate advice to give a patient taking a typical antipsychotic medication?
How often is the depot or decanoate form of a typical antipsychotic medication typically administered?
How often is the depot or decanoate form of a typical antipsychotic medication typically administered?
Which of the following statements about typical antipsychotics is correct?
Which of the following statements about typical antipsychotics is correct?
Which of the following factors should guide the choice of a specific antipsychotic medication?
Which of the following factors should guide the choice of a specific antipsychotic medication?
Which of the following statements about the pharmacokinetics of typical antipsychotics is incorrect?
Which of the following statements about the pharmacokinetics of typical antipsychotics is incorrect?
Which of the following statements about drug interactions with typical antipsychotics is correct?
Which of the following statements about drug interactions with typical antipsychotics is correct?
Which of the following statements about the pharmacokinetics of atypical antipsychotics is correct?
Which of the following statements about the pharmacokinetics of atypical antipsychotics is correct?
Which of the following atypical antipsychotics is primarily excreted through feces?
Which of the following atypical antipsychotics is primarily excreted through feces?
