Antimicrobial Pharmacology 1: Bacterial Cell Wall and Folic Acid Metabolism
29 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary difference between Gram-positive and Gram-negative bacteria?

  • The presence of porins in Gram-positive bacteria
  • The presence of a plasma membrane in Gram-negative bacteria
  • The structure of their cell walls (correct)
  • The presence of lipopolysaccharide in Gram-positive bacteria
  • What is the term used to describe drugs that kill bacteria?

  • Antifungals
  • Antiparasitics
  • Antivirals
  • Antibiotics (correct)
  • Which of the following bacteria is responsible for causing tuberculosis?

  • C. tetani
  • B. anthrax
  • M. leprae
  • M. tuberculosis (correct)
  • What is the function of porins in Gram-negative bacteria?

    <p>To allow for the passage of certain molecules</p> Signup and view all the answers

    Which of the following is an example of a Gram-positive bacterium that can cause wound infections?

    <p>S. Aureus</p> Signup and view all the answers

    What is the term used to describe drugs that target folic acid metabolism?

    <p>Sulfonamides</p> Signup and view all the answers

    What is the morphology of the bacteria species Campylobacter Jejuni?

    <p>Spiral rods</p> Signup and view all the answers

    Which bacteria is responsible for causing Whooping cough?

    <p>Bordetella Pertussis</p> Signup and view all the answers

    What is the disease caused by the bacteria Neisseria Gonorrhoeae?

    <p>Gonorrhea</p> Signup and view all the answers

    Which of the following bacteria is capable of causing Septicemia and UTIs?

    <p>All of the above</p> Signup and view all the answers

    What is the morphology of the bacteria species Helicobacter Pyroli?

    <p>Motile rods</p> Signup and view all the answers

    What is the primary mechanism of action of sulfonamides?

    <p>Competitively inhibiting dihydropteroate synthetase</p> Signup and view all the answers

    What is the effect of combining sulfonamides with folic acid antagonists?

    <p>Potentiating the action on decreasing bacterial DNA/RNA synthesis</p> Signup and view all the answers

    Which of the following antibiotics is an anti-malarial?

    <p>Sulfadoxine</p> Signup and view all the answers

    What is the function of the enzyme associated with PBP?

    <p>To perform construction, repair, and housekeeping</p> Signup and view all the answers

    What is the primary mechanism of action of β-lactam antibiotics?

    <p>Inhibiting the enzymes processing the developing peptidoglycan layer</p> Signup and view all the answers

    What is the mechanism of action of β-lactam antibiotics?

    <p>Inhibiting the synthesis of peptidoglycan</p> Signup and view all the answers

    What is a common adverse effect of folic acid antagonists?

    <p>Folate deficiency</p> Signup and view all the answers

    Which of the following penicillins is sensitive to β-lactamase?

    <p>Penicillin G</p> Signup and view all the answers

    How are sulfonamides primarily metabolized?

    <p>By the liver</p> Signup and view all the answers

    What is the characteristic of Ampicillin?

    <p>Good oral availability and active against gram-positive and negative bacteria</p> Signup and view all the answers

    Which of the following is an indication for the use of Penicillins?

    <p>Bone and joint infections</p> Signup and view all the answers

    What is the function of Clavulanic acid?

    <p>To inhibit the activity of β-lactamase</p> Signup and view all the answers

    What percentage of penicillins are eliminated via renal tubular secretion?

    <p>90%</p> Signup and view all the answers

    Which of the following is a common adverse effect of penicillins?

    <p>GI disturbances</p> Signup and view all the answers

    What is the mechanism of action of cephalosporins?

    <p>Irreversible inhibition of PBPs</p> Signup and view all the answers

    Which of the following cephalosporins is commonly used to treat sinusitis?

    <p>Cefaclor</p> Signup and view all the answers

    What is a common adverse effect of carbapenems?

    <p>Diarrhea</p> Signup and view all the answers

    Which of the following is a contraindication for cephalosporin use?

    <p>Anaphylaxis to penicillins</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser