Antimicrobial Drugs Mechanism Quiz
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Questions and Answers

What is the mechanism of action of bacteriostatic antibiotics?

  • Killing bacteria
  • Inhibiting protein synthesis
  • Disrupting bacterial cell wall synthesis
  • Preventing bacterial reproduction (correct)
  • Which of the following is a characteristic of probiotics?

  • They bind to mucosa receptor sites (correct)
  • They kill pathogenic bacteria directly
  • They are chemical antibiotics
  • They are synthetic compounds
  • Which antibiotic is classified as bactericidal?

  • Macrolides
  • Polymyxins
  • Penicillins (correct)
  • Tetracyclines
  • What is the spectrum of activity for macrolides?

    <p>Act mainly against gram-positive organisms</p> Signup and view all the answers

    Which enzyme in bacteria is much more active against dihydrofolic acid compared to mammalian cells?

    <p>Tetrahydrofolic acid reductase</p> Signup and view all the answers

    Which combination of antimicrobial agents shows synergism due to sequential blocking of the folic acid synthesis pathway?

    <p>Sulfonamides + trimethoprim</p> Signup and view all the answers

    Which type of bacteria resistance mechanism involves producing enzymes that destroy the active drug?

    <p>Beta-lactamase</p> Signup and view all the answers

    What adverse effect is associated with the use of trimethoprim?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    Which antimicrobial agent works by inhibiting cell membrane function?

    <p>Tigecycline</p> Signup and view all the answers

    What type of enzymes do bacteria resistant to aminoglycosides produce to destroy the drug?

    <p>Phosphorylating enzymes</p> Signup and view all the answers

    Which type of anti-microbial drugs act on the 30 S subunit?

    <p>Aminoglycosides</p> Signup and view all the answers

    Which anti-microbial drug is considered bactericidal?

    <p>Aminoglycosides</p> Signup and view all the answers

    What is the mechanism of resistance to aminoglycosides?

    <p>Bacterial transferase enzymes inactivate the drug by acetylation, phosphorylation, or adenylation</p> Signup and view all the answers

    Which anti-microbial drug is known to be teratogenic and cause teeth discoloration?

    <p>Tetracyclines</p> Signup and view all the answers

    What is the clinical use of tetracyclines like doxycycline?

    <p>Treatment of Borrelia burgdorferi and intracellular bacteria like Chlamydia</p> Signup and view all the answers

    Which bacteria are aminoglycosides like streptomycin used to treat?

    <p>Tuberculosis-causing bacteria</p> Signup and view all the answers

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