Antimicrobial Drugs Mechanism Quiz

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Questions and Answers

What is the mechanism of action of bacteriostatic antibiotics?

  • Killing bacteria
  • Inhibiting protein synthesis
  • Disrupting bacterial cell wall synthesis
  • Preventing bacterial reproduction (correct)

Which of the following is a characteristic of probiotics?

  • They bind to mucosa receptor sites (correct)
  • They kill pathogenic bacteria directly
  • They are chemical antibiotics
  • They are synthetic compounds

Which antibiotic is classified as bactericidal?

  • Macrolides
  • Polymyxins
  • Penicillins (correct)
  • Tetracyclines

What is the spectrum of activity for macrolides?

<p>Act mainly against gram-positive organisms (C)</p> Signup and view all the answers

Which enzyme in bacteria is much more active against dihydrofolic acid compared to mammalian cells?

<p>Tetrahydrofolic acid reductase (A)</p> Signup and view all the answers

Which combination of antimicrobial agents shows synergism due to sequential blocking of the folic acid synthesis pathway?

<p>Sulfonamides + trimethoprim (B)</p> Signup and view all the answers

Which type of bacteria resistance mechanism involves producing enzymes that destroy the active drug?

<p>Beta-lactamase (B)</p> Signup and view all the answers

What adverse effect is associated with the use of trimethoprim?

<p>Megaloblastic anemia (A)</p> Signup and view all the answers

Which antimicrobial agent works by inhibiting cell membrane function?

<p>Tigecycline (B)</p> Signup and view all the answers

What type of enzymes do bacteria resistant to aminoglycosides produce to destroy the drug?

<p>Phosphorylating enzymes (D)</p> Signup and view all the answers

Which type of anti-microbial drugs act on the 30 S subunit?

<p>Aminoglycosides (B)</p> Signup and view all the answers

Which anti-microbial drug is considered bactericidal?

<p>Aminoglycosides (D)</p> Signup and view all the answers

What is the mechanism of resistance to aminoglycosides?

<p>Bacterial transferase enzymes inactivate the drug by acetylation, phosphorylation, or adenylation (A)</p> Signup and view all the answers

Which anti-microbial drug is known to be teratogenic and cause teeth discoloration?

<p>Tetracyclines (B)</p> Signup and view all the answers

What is the clinical use of tetracyclines like doxycycline?

<p>Treatment of Borrelia burgdorferi and intracellular bacteria like Chlamydia (B)</p> Signup and view all the answers

Which bacteria are aminoglycosides like streptomycin used to treat?

<p>Tuberculosis-causing bacteria (A)</p> Signup and view all the answers

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