Antimicrobial Drug Summary
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Questions and Answers

Which antibiotics are recommended for treating difficile infection?

Vancomycin (oral), Fidaxomicin, Metronidazole

Name some antibiotics effective against Atypical Organisms.

Azithromycin, clarithromycin, Doxycycline, minocycline

What antibiotics are suggested for treating Extended spectrum beta-lactamase producing Gram-negative rods (ESBL GNR)?

Carbapenems, Tigecycline, Ceftolozane/Tazobactam

What are the drugs of choice for community-associated methicillin-resistant Staphylococcus aureus (CA MRSA) skin & soft tissue infections (SSTIs)?

<p>SMX/TMP, doxycycline, minocycline, clindamycin, linezolid</p> Signup and view all the answers

What are the drugs of choice for VRE (E. faecium) infections?

<p>Daptomycin, linezolid</p> Signup and view all the answers

What are the drugs of choice for carbapenem-resistant Gram-negative rods (CRE)?

<p>Linezolid, ceftazidime/avibactam, quinupristin/dalfopristin, colistimethate, polymyxin B, tigecycline</p> Signup and view all the answers

What are the drugs of choice for nosocomial MRSA infections?

<p>Vancomycin, linezolid, daptomycin, rifampin, telavancin</p> Signup and view all the answers

Which antibiotics are recommended for more severe skin and soft tissue infections requiring IV treatment or hospitalization, covering MRSA and Streptococci?

<p>Vancomycin, linezolid, tedizolid, ceftazidime/avibactam, cefepime, tigecycline, ceftazidime, clindamycin, moxifloxacin, daptomycin, ceftolozane/tazobactam, ceftaroline, carbapenems (except ertapenem), telavancin, ciprofloxacin, levofloxacin, oritavancin, aztreonam, dalbavancin, aminoglycosides, quinupristin/dalfopristin, colistimethate, polymyxin B, and tigecycline.</p> Signup and view all the answers

Which antibiotics are recommended for cystitis caused by carbapenem-resistant Gram-negative rods (CRE)?

<p>Nitrofurantoin, fosfomycin, doxycycline.</p> Signup and view all the answers

What are the drugs of choice for Acinetobacter baumannii infections?

<p>Nosocomial MRSA infections can be treated with vancomycin (consider using alternative if MIC &gt; 2), linezolid, daptomycin (not in pneumonia), rifampin (select infections, never used alone), and telavancin.</p> Signup and view all the answers

What are the recommended antibiotics for VRE (E. faecalis) infections?

<p>Penicillin G or ampicillin, linezolid, daptomycin, and carbapenems.</p> Signup and view all the answers

Which antibiotics are recommended for treating Pseudomonas aeruginosa infections?

<p>Piperacillin/Tazobactam, Ceftolozane/Tazobactam, Aminoglycosides, Cefepime (high-dose), Carbapenems</p> Signup and view all the answers

Name some antibiotics effective against HNPEK organisms.

<p>Ampicillin/Sulbactam, Quinolones, Amoxicillin (if beta-lactamase negative), Cefotetan, Cefoxitin, Cephalosporins (except 1st generation), Carbapenems, SMX/TMP, Aminoglycosides</p> Signup and view all the answers

What antibiotics are suggested for treating cystitis caused by ESBL GNR?

<p>Ceftolozane/Tazobactam, Tigecycline, Cystitis only: nitrofurantoin, fosfomycin, Ceftazidime/Avibactam</p> Signup and view all the answers

Which antibiotics are recommended for treating difficile infection?

<p>Vancomycin (oral), Fidaxomicin, Metronidazole</p> Signup and view all the answers

Name some antibiotics effective against Atypical Organisms.

<p>Azithromycin, clarithromycin, Doxycycline, minocycline</p> Signup and view all the answers

What are the drugs of choice for Acinetobacter baumannii infections?

<p>Carbapenems, Sulbactam, Ampicillin</p> Signup and view all the answers

Name four antibiotics recommended for treating nosocomial MRSA infections.

<p>Vancomycin, Linezolid, Daptomycin, Rifampin</p> Signup and view all the answers

List four antibiotics suggested for treating Acinetobacter baumannii infections.

<p>Vancomycin, Linezolid, Daptomycin, Rifampin</p> Signup and view all the answers

What are the four drugs of choice for VRE (E. faecalis) infections?

<p>Penicillin G or ampicillin, Linezolid, Daptomycin, Carbapenems</p> Signup and view all the answers

Name four antibiotics recommended for treating carbapenem-resistant Gram-negative rods (CRE).

<p>Linezolid, Ceftazidime/Avibactam, Quinupristin/Dalfopristin, Colistimethate</p> Signup and view all the answers

Which liquid oral antibiotics should be refrigerated after reconstitution?

<p>Penicillin VK, Ampicillin, Amoxicillin/Clavulanate (Augmentin), Cephalexin (Keflex)</p> Signup and view all the answers

Why is refrigeration recommended for Amoxicillin?

<p>Refrigeration is recommended for Amoxicillin to improve taste.</p> Signup and view all the answers

Name some key drugs that do not require renal dose adjustments.

<p>Antistaphylococcal penicillins (e.g., dicloxacillin, nafcillin), Ceftriaxone, Clindamycin, Doxycycline, Macrolides (azithromycin and erythromycin only), Metronidazole, Moxifloxacin, Linezolid</p> Signup and view all the answers

Which liquid oral antibiotics should be refrigerated after reconstitution?

<p>Penicillin VK, Ampicillin, Amoxicillin/Clavulanate (Augmentin), Cephalexin (Keflex)</p> Signup and view all the answers

What are the key drugs that do not require renal dose adjustments?

<p>Antistaphylococcal penicillins (e.g., dicloxacillin, nafcillin), Ceftriaxone, Clindamycin, Doxycycline, Macrolides (azithromycin and erythromycin only), Metronidazole, Moxifloxacin, Linezolid</p> Signup and view all the answers

Why is refrigeration recommended for Amoxicillin?

<p>Refrigeration for Amoxicillin is recommended to improve taste.</p> Signup and view all the answers

List four liquid oral antibiotics that should be refrigerated after reconstitution.

<p>Penicillin VK, Ampicillin, Amoxicillin/Clavulanate (Augmentin), Cephalexin (Keflex)</p> Signup and view all the answers

Name four key drugs that do not require renal dose adjustments.

<p>Antistaphylococcal penicillins (e.g., dicloxacillin, nafcillin), Ceftriaxone, Clindamycin, Doxycycline</p> Signup and view all the answers

Which liquid oral antibiotic is recommended for refrigeration to improve taste?

<p>Amoxicillin</p> Signup and view all the answers

Which antibiotics should be taken on an empty stomach according to the RxPrep Course Book?

<p>ampicillin oral capsules and suspension, ceftibuten suspension, levofloxacin oral solution, penicillin VK, rifampin, isoniazid, itraconazole solution, voriconazole</p> Signup and view all the answers

What are some examples of antibiotics that should be taken within one hour of finishing a meal according to the RxPrep Course Book?

<p>amoxicillin ER</p> Signup and view all the answers

Which drugs have the same oral and IV dosing according to the RxPrep Course Book?

<p>Levofloxacin, moxifloxacin, Doxycycline, minocycline, Sulfamethoxazole/ Trimethoprim, Linezolid, tedizolid, Metronidazole, Fluconazole, isavuconazonium, posaconazole, voriconazole</p> Signup and view all the answers

What are some antibiotics that require specific light protection during administration according to the RxPrep Course Book?

<p>Doxycycline, Micafungin, Pentamidine</p> Signup and view all the answers

Which antibiotics should be taken on an empty stomach according to the RxPrep Course Book?

<p>ampicillin oral capsules and suspension, ceftibuten suspension, levofloxacin oral solution, penicillin VK, rifampin, isoniazid, itraconazole solution, voriconazole</p> Signup and view all the answers

Name some antibiotics that require specific light protection during administration according to the RxPrep Course Book.

<p>Doxycycline, Micafungin, Pentamidine</p> Signup and view all the answers

For which drugs is the oral and IV dose the same according to the RxPrep Course Book?

<p>Levofloxacin, moxifloxacin, Doxycycline, minocycline, Sulfamethoxazole/Trimethoprim, Linezolid, tedizolid, Metronidazole, Fluconazole, isavuconazonium, posaconazole, voriconazole</p> Signup and view all the answers

Which antibiotics can be taken with food to decrease GI upset, except for the ones mentioned in the RxPrep Course Book?

<p>amoxicillin ER</p> Signup and view all the answers

What antibiotics should be taken on an empty stomach according to the RxPrep Course Book?

<p>ampicillin oral capsules and suspension, ceftibuten suspension, levofloxacin oral solution, penicillin VK, rifampin, isoniazid, itraconazole solution, voriconazole</p> Signup and view all the answers

For which drugs is the oral and IV dose the same according to the RxPrep Course Book?

<p>levofloxacin, moxifloxacin, doxycycline, minocycline, sulfamethoxazole/trimethoprim, linezolid, tedizolid, metronidazole, fluconazole, isavuconazonium, posaconazole, voriconazole</p> Signup and view all the answers

Name some antibiotics that require specific light protection during administration according to the RxPrep Course Book.

<p>doxycycline, micafungin, pentamidine</p> Signup and view all the answers

What are the diluent compatibility requirements for certain drugs according to the RxPrep Course Book?

<p>Refer to the Learning IV Medications chapter for a complete list of drugs (including antibiotics and other drugs) that require specific diluents.</p> Signup and view all the answers

What is the primary type of infection that antibiotics treat?

<p>Antibiotics only treat bacterial infections. They do not treat viral infections.</p> Signup and view all the answers

What are the potential consequences of skipping antibiotic doses or not completing the full course of treatment?

<p>Skipping doses or not completing the full course of treatment can reduce the effects, cause the infection to return, and increase the likelihood that the medication will not work in the future.</p> Signup and view all the answers

What should be done if a patient experiences a rash while taking antibiotics?

<p>If a patient experiences a rash while taking antibiotics, they should contact their healthcare provider.</p> Signup and view all the answers

How should liquid doses of antibiotics be measured, and why is it important to use the appropriate measuring device?

<p>Liquid doses of antibiotics should be measured carefully using the measuring device/syringe that comes with the medication. It's important to use the appropriate measuring device because household spoons often do not deliver the correct dose.</p> Signup and view all the answers

List two potential side effects of the medication discussed in the text.

<p>Dark urine and serious lung problems</p> Signup and view all the answers

What should you do if you notice dark urine along with persistent nausea or vomiting, pale stools, unusual fatigue, or yellowing of the skin and eyes?

<p>Seek immediate medical attention</p> Signup and view all the answers

How should the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) be applied?

<p>Place half the ointment from the tube into each nostril, press the nostrils at the same time, and let go many times for about 1 minute to spread the ointment into the nose</p> Signup and view all the answers

What are the most common side effects of the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>Burning and itching</p> Signup and view all the answers

How should Amoxicillin ER be taken for optimal absorption and to minimize stomach upset?

<p>Amoxicillin ER should be taken within 1 hour of finishing a meal.</p> Signup and view all the answers

What are the administration guidelines for Augmentin to enhance absorption and reduce stomach upset?

<p>Augmentin should be taken with food.</p> Signup and view all the answers

How should Cephalexin (Keflex) be taken and how often?

<p>Cephalexin (Keflex) can be taken with or without food every six hours.</p> Signup and view all the answers

What are the administration guidelines for Cefuroxime in relation to food and frequency?

<p>Cefuroxime should be taken with food every 12 hours.</p> Signup and view all the answers

How should Cefdinir be taken in relation to food, and should its suspension be refrigerated?

<p>Cefdinir can be taken with or without food, and its suspension should not be refrigerated.</p> Signup and view all the answers

When should Penicillin VK be taken in relation to a meal, and should its suspension be refrigerated?

<p>Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.</p> Signup and view all the answers

What substances can interact with Quinolones, affecting their efficacy, and what should they not be taken with?

<p>Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins. They should not be taken with dairy products.</p> Signup and view all the answers

What are some potential side effects and interactions associated with Quinolones?

<p>Quinolones can cause tendon inflammation or rupture, increase the risk for seizures, and lead to various other side effects, such as skin sensitivity to the sun.</p> Signup and view all the answers

What are the specific administration guidelines for Ciprofloxacin in terms of its use with tizanidine and refrigeration of its liquid suspension?

<p>Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.</p> Signup and view all the answers

How should Levofloxacin be taken in relation to food and refrigeration of its suspension?

<p>Levofloxacin should be taken once daily, with or without food, and its suspension should not be refrigerated.</p> Signup and view all the answers

What specific considerations should be taken into account for the administration and storage of Azithromycin and clarithromycin?

<p>Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.</p> Signup and view all the answers

What should be done when taking Doxycycline and minocycline to avoid potential side effects?

<p>Doxycycline and minocycline should be taken with a full glass of water to avoid gastrointestinal irritation.</p> Signup and view all the answers

Explain the importance of completing the full course of antibiotic treatment and the potential consequences of not doing so.

<p>Completing the full course of antibiotic treatment is important to ensure that the infection is fully eradicated and to prevent the development of antibiotic resistance. Skipping doses or not completing the full course of treatment can reduce the effectiveness of the medication, cause the infection to return, and increase the likelihood that the medication will not work for you in the future.</p> Signup and view all the answers

What are the potential side effects of many antibiotics, and how should patients respond if they experience these side effects?

<p>Many antibiotics can cause rash and GI upset. If a patient experiences a rash or GI upset, they should contact their healthcare provider for guidance. Additionally, if the patient has watery diarrhea several times a day, with or without abdominal cramping, they should also contact their healthcare provider, especially if it occurs during treatment or weeks after the antibiotic treatment has finished.</p> Signup and view all the answers

What precautions should be taken when measuring liquid doses of antibiotics, and why should household spoons not be used for this purpose?

<p>Liquid doses of antibiotics should be measured carefully using the measuring device/syringe that comes with the medication. Household spoons should not be used, as they often do not deliver the correct dose. It is important to use the appropriate measuring device to ensure accurate dosing and avoid potential dosing errors.</p> Signup and view all the answers

How should Amoxicillin be taken in relation to food, and what potential side effects should patients be aware of?

<p>Amoxicillin can be taken with or without food. Patients should be aware that Amoxicillin can cause rash and GI upset, and they should contact their healthcare provider if they experience these side effects.</p> Signup and view all the answers

How should Amoxicillin ER be taken for optimal absorption and to minimize stomach upset?

<p>Amoxicillin ER should be taken within 1 hour of finishing a meal to maximize absorption and minimize stomach upset.</p> Signup and view all the answers

What are the administration guidelines for Augmentin to enhance absorption and reduce stomach upset?

<p>Augmentin should be taken with food to enhance absorption and reduce stomach upset.</p> Signup and view all the answers

How should Cephalexin (Keflex) be taken and how often?

<p>Cephalexin (Keflex) can be taken with or without food every six hours.</p> Signup and view all the answers

How should Cefuroxime be taken in relation to food and frequency?

<p>Cefuroxime should be taken with food every 12 hours.</p> Signup and view all the answers

How should Levofloxacin be taken in relation to food and refrigeration of its suspension?

<p>Levofloxacin should be taken once daily, with or without food, and its suspension should not be refrigerated.</p> Signup and view all the answers

What are the specific administration guidelines for Ciprofloxacin in terms of its use with tizanidine and refrigeration of its liquid suspension?

<p>Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.</p> Signup and view all the answers

What consequences can Quinolones have when interacting with certain substances?

<p>Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins, affecting their efficacy.</p> Signup and view all the answers

What are some potential side effects of Quinolones?

<p>Quinolones can cause tendon inflammation or rupture, increase the risk for seizures, and lead to various other side effects, such as skin sensitivity to the sun.</p> Signup and view all the answers

How should Doxycycline and minocycline be taken to avoid potential side effects?

<p>Doxycycline and minocycline should be taken with a full glass of water to avoid gastrointestinal irritation.</p> Signup and view all the answers

What are the specific storage instructions for Cefdinir's suspension?

<p>Cefdinir's suspension should not be refrigerated.</p> Signup and view all the answers

When should Penicillin VK be taken in relation to a meal, and should its suspension be refrigerated?

<p>Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.</p> Signup and view all the answers

What specific dosing regimens and storage instructions are there for Azithromycin and clarithromycin?

<p>Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.</p> Signup and view all the answers

What are the potential serious side effects of the medication mentioned in the text?

<p>Dark brown urine indicating liver damage and possibly fatal lung problems.</p> Signup and view all the answers

What should you do if you notice dark urine along with persistent nausea or vomiting, pale stools, unusual fatigue, or yellowing of the skin and eyes?

<p>Seek immediate medical attention.</p> Signup and view all the answers

What is the application method for the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>Place half of the ointment from the tube into each nostril and press the nostrils to spread the ointment into the nose for about 1 minute.</p> Signup and view all the answers

What are the most common side effects of the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>Burning and itching are the most common side effects.</p> Signup and view all the answers

Name two potential serious side effects of the medication discussed in the text.

<p>Dark urine as a sign of liver damage and possibly fatal lung problems</p> Signup and view all the answers

What are the most common side effects of the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>Burning and itching</p> Signup and view all the answers

How should the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) be applied?

<p>Place half the ointment from the tube into one nostril and the other half into the other nostril. Press the nostrils at the same time and let go; do this many times (for about 1 minute) to spread the ointment into the nose. Wash your hands after use.</p> Signup and view all the answers

Where are the guidelines available for this medication?

<p>Guidelines available at the Infectious Diseases Society of America website (<a href="http://www.idsociety.org">www.idsociety.org</a>)</p> Signup and view all the answers

Explain the potential consequences of skipping doses or not completing the full course of antibiotic treatment.

<p>Skipping doses or not completing the full course of treatment can lessen the effects, cause the infection to return, and increase the likelihood that the medication will not work for you in the future.</p> Signup and view all the answers

What should be done if a patient experiences a rash while taking antibiotics?

<p>If a patient experiences a rash while taking antibiotics, they should contact their healthcare provider.</p> Signup and view all the answers

What should a patient do if they have watery diarrhea several times a day during or after antibiotic treatment?

<p>If a patient has watery diarrhea several times a day during or after antibiotic treatment, they should contact their healthcare provider and not self-treat with anti-diarrheal medication.</p> Signup and view all the answers

Why is it important to measure liquid antibiotic doses carefully and avoid using household spoons?

<p>It is important to measure liquid antibiotic doses carefully using the provided measuring device/syringe to ensure the correct dose. Household spoons should not be used, as they often do not deliver the correct dose.</p> Signup and view all the answers

How should Amoxicillin ER be taken for optimal absorption and to minimize stomach upset?

<p>Amoxicillin ER should be taken within 1 hour of finishing a meal.</p> Signup and view all the answers

What are the administration guidelines for Augmentin to enhance absorption and reduce stomach upset?

<p>Augmentin should be taken with food.</p> Signup and view all the answers

How should Cephalexin (Keflex) be taken in relation to food and frequency?

<p>Cephalexin (Keflex) can be taken with or without food every six hours.</p> Signup and view all the answers

What are the administration guidelines for Cefuroxime in terms of food and frequency?

<p>Cefuroxime should be taken with food every 12 hours.</p> Signup and view all the answers

How should Cefdinir be taken in relation to food, and should its suspension be refrigerated?

<p>Cefdinir can be taken with or without food, and its suspension should not be refrigerated.</p> Signup and view all the answers

When should Penicillin VK be taken in relation to a meal, and should its suspension be refrigerated?

<p>Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.</p> Signup and view all the answers

What substances can interact with Quinolones, affecting their efficacy, and what should they not be taken with?

<p>Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins. They should not be taken with dairy products.</p> Signup and view all the answers

What are the specific administration guidelines for Ciprofloxacin in terms of its use with tizanidine and refrigeration of its liquid suspension?

<p>Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.</p> Signup and view all the answers

How should Levofloxacin be taken in terms of food and frequency?

<p>Levofloxacin should be taken once daily, with or without food.</p> Signup and view all the answers

What are the specific dosing and storage instructions for Azithromycin and clarithromycin?

<p>Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.</p> Signup and view all the answers

What are the potential side effects of Doxycycline and minocycline?

<p>Doxycycline and minocycline can increase skin sensitivity to the sun and should be taken with a full glass of water to avoid gastrointestinal irritation.</p> Signup and view all the answers

What precautions should be taken when measuring liquid doses of antibiotics, and why should household spoons not be used for this purpose?

<p>It is important to use the appropriate measuring device for liquid doses of antibiotics, and household spoons should not be used as they may not provide accurate measurements.</p> Signup and view all the answers

What are the potential side effects of using the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>The potential side effects of using the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) include dark yellow or brown urine, burning, itching, and possibly fatal lung problems.</p> Signup and view all the answers

What symptoms should prompt immediate medical attention when using the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>Immediate medical attention should be sought if dark urine is accompanied by persistent nausea or vomiting, pale stools, unusual fatigue, yellowing of the skin and whites of the eyes, or symptoms of lung problems such as persistent cough, chest pain, shortness of breath, joint/muscle pain, or bluish/purplish skin.</p> Signup and view all the answers

How should the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) be applied?

<p>The 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) should be applied by placing a small amount into each nostril and pressing the nostrils together to spread the ointment into the nose. This process should be repeated multiple times for about 1 minute. Hands should be washed after use.</p> Signup and view all the answers

What are the most common side effects of using the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL)?

<p>The most common side effects of using the 774 MUPIROCIN OINTMENT (BACTROBAN NASAL) are burning and itching.</p> Signup and view all the answers

Study Notes

Antibiotic Medication Administration Guidelines

  • Amoxicillin ER should be taken within 1 hour of finishing a meal to maximize absorption and minimize stomach upset.
  • Augmentin should be taken with food to enhance absorption and reduce stomach upset; its suspension should be refrigerated.
  • Cephalexin (Keflex) can be taken with or without food every six hours, and its suspension should be refrigerated.
  • Cefuroxime should be taken with food every 12 hours, and its suspension should be refrigerated.
  • Cefdinir can be taken with or without food, and its suspension should not be refrigerated.
  • Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.
  • Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins, affecting their efficacy. They should be taken at specific intervals in relation to these substances and should not be taken with dairy products.
  • Quinolones can cause tendon inflammation or rupture, increase the risk for seizures, and lead to various other side effects, such as skin sensitivity to the sun.
  • Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.
  • Levofloxacin should be taken once daily, with or without food, and its suspension should not be refrigerated.
  • Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.
  • Doxycycline and minocycline can increase skin sensitivity to the sun and should be taken with a full glass of water to avoid gastrointestinal irritation.

Antibiotic Medication Administration Guidelines

  • Amoxicillin ER should be taken within 1 hour of finishing a meal to maximize absorption and minimize stomach upset.
  • Augmentin should be taken with food to enhance absorption and reduce stomach upset; its suspension should be refrigerated.
  • Cephalexin (Keflex) can be taken with or without food every six hours, and its suspension should be refrigerated.
  • Cefuroxime should be taken with food every 12 hours, and its suspension should be refrigerated.
  • Cefdinir can be taken with or without food, and its suspension should not be refrigerated.
  • Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.
  • Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins, affecting their efficacy. They should be taken at specific intervals in relation to these substances and should not be taken with dairy products.
  • Quinolones can cause tendon inflammation or rupture, increase the risk for seizures, and lead to various other side effects, such as skin sensitivity to the sun.
  • Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.
  • Levofloxacin should be taken once daily, with or without food, and its suspension should not be refrigerated.
  • Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.
  • Doxycycline and minocycline can increase skin sensitivity to the sun and should be taken with a full glass of water to avoid gastrointestinal irritation.

Antibiotic Medication Administration Guidelines

  • Amoxicillin ER should be taken within 1 hour of finishing a meal to maximize absorption and minimize stomach upset.
  • Augmentin should be taken with food to enhance absorption and reduce stomach upset; its suspension should be refrigerated.
  • Cephalexin (Keflex) can be taken with or without food every six hours, and its suspension should be refrigerated.
  • Cefuroxime should be taken with food every 12 hours, and its suspension should be refrigerated.
  • Cefdinir can be taken with or without food, and its suspension should not be refrigerated.
  • Penicillin VK should be taken one hour before or two hours after a meal, and its suspension should be refrigerated.
  • Quinolones can interact with antacids, didanosine, sucralfate, bile acid resins, and various minerals and vitamins, affecting their efficacy. They should be taken at specific intervals in relation to these substances and should not be taken with dairy products.
  • Quinolones can cause tendon inflammation or rupture, increase the risk for seizures, and lead to various other side effects, such as skin sensitivity to the sun.
  • Ciprofloxacin should not be used with tizanidine, and its liquid suspension should not be refrigerated.
  • Levofloxacin should be taken once daily, with or without food, and its suspension should not be refrigerated.
  • Azithromycin and clarithromycin have specific dosing regimens and storage instructions for their tablets and suspensions.
  • Doxycycline and minocycline can increase skin sensitivity to the sun and should be taken with a full glass of water to avoid gastrointestinal irritation.

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Test your knowledge of drug choices for specific pathogens with this RxPrep summary tables quiz. Identify the drugs of choice for community-associated methicillin-resistant Staphylococcus aureus (CA MRSA), vancomycin-resistant Enterococcus (VRE), and carbapenem-resistant Gram-negative rods (CRE) among others.

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