12 Questions
What is the mechanism observed in the imipenem-colistin combination at low crestor concentrations?
Synergy-like effect
What was the only variable significantly associated with mortality in the study?
Cardiovascular illness
Why is sulbactam preferred over clavulanic acid in Acinetobacter infections?
Because sulbactam is more active peripherally
What type of patients are at risk of Acinetobacter infections?
Patients with urinary catheters, central line catheters, and wound infections
What is the name of the bacterium that is associated with the usage of urethral catheters, central line catheters, and wound infections?
A. calcoaceticus
What is the term used to describe the comprehensive criteria used to evaluate the clinical efficacy of the drug combinations?
Favorable clinical response criteria
What percentage of Gram-negative infections in Intensive Care Units are attributed to baumannii complex?
60%
What is essential for an effective infection control program with minimal intervention?
Frequent monitoring of body fluids
What is a major concern regarding the use of carbapenems in treating Acinetobacter infections?
Emergence of resistant isolates worldwide
What is a promising avenue for combating CRAB infections, according to in vivo studies?
Sulbactam combinations
Why is sulbactam not affected by hemodialysis?
It is not removed by kidney function
What is a consequence of the increased use of carbapenems in treating E. coli and Salmonella infections?
Increased resistance to carbapenems
Compare the efficacy of imipenem-sulbactam and imipenem-colistin combinations in treating bacterial infections. Evaluate the in vitro potency and clinical outcomes of these antimicrobial therapies.
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