Antimicrobial Chemotherapy Mechanism of Action

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10 Questions

Which antibiotic shares a B-lactam ring in its molecular structure?

Penicillins

What is the mechanism of action of Vancomycin?

Inhibition of bacterial cell wall synthesis

What is the general adverse effect associated with broad-spectrum antibiotics?

Superinfection

What is the treatment for superinfection caused by broad-spectrum antibiotics with incomplete absorption?

Stop antibiotic and administer Metronidazole orally for bacteria

Which antibiotics decrease bacterial cell wall synthesis?

Penicillins & Cephalosporin

Which antibiotic is inactivated by B-lactamase and is usually combined with clavulanic acid or sulbactam to cover B-lactamase producing bacteria?

Amoxicillin

Which antibiotic is only effective against Gram-positive bacteria and is commonly used to treat Methicillin-resistant Staphylococcus Aureus (MRSA)?

Vancomycin

Which antibiotic has a high incidence of diarrhea and pseudomembranous colitis as a side effect due to superinfection, and is similar in mechanism to erythromycin?

Clindamycin

Which antibiotic class tends to be deposited in growing bones and teeth causing yellow discoloration of teeth due to its chelating properties with calcium?

Tetracyclines

Which antibiotic inhibits nucleic acid synthesis (DNA) and should have its empiric use in minor infections discouraged?

Ciprofloxacin

Test your knowledge of antimicrobial chemotherapy by classifying according to their mechanism of action and general adverse effects.

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