Antimicrobial Agents Quiz

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Questions and Answers

What are antibiotics?

  • Chemical substances that kill or inhibit the growth of microorganisms produced by humans
  • Chemical substances that kill or inhibit the growth of microorganisms produced by plants
  • Chemical substances that kill or inhibit the growth of microorganisms produced by animals
  • Chemical substances that kill or inhibit the growth of microorganisms produced by other microorganisms (correct)

Which of the following is NOT a producer of antibiotics?

  • Virus (correct)
  • Actinomycetes
  • Fungi
  • Bacillus

Which of the following microorganisms is not a producer of antibiotics?

  • Actinomycetes
  • Bacteria
  • Fungi
  • Virus (correct)

What is the mode of action of antibiotics?

<p>Inhibition of cell wall synthesis, protein synthesis, cell membrane, DNA/RNA synthesis (A)</p> Signup and view all the answers

Which antibiotic inhibits cell wall synthesis by binding to the last D-alanine?

<p>Vancomycin (A)</p> Signup and view all the answers

Which antibiotic inhibits cell wall synthesis through transpeptidation?

<p>Penicillin (B)</p> Signup and view all the answers

Which antibiotic prevents peptide bond formation and is effective against obligate anaerobic bacteria?

<p>Clindomycin (D)</p> Signup and view all the answers

Which antibiotic prevents initiation of protein synthesis?

<p>Streptomycin (C)</p> Signup and view all the answers

Which antibiotic binds to the last D-alanine, stops removal by blocking enzymes?

<p>Vancomycin (D)</p> Signup and view all the answers

Which antibiotic prevents translocation?

<p>Erythromycin (A)</p> Signup and view all the answers

Which antibiotic binds to DNA and prevents replication and transcription?

<p>Actinomycin (A)</p> Signup and view all the answers

Which antibiotic distorts the phospholipid bilayer by altering the semi-permeability?

<p>Polymyxin (D)</p> Signup and view all the answers

Which antibiotic inhibits peptide bond formation and causes dissociation of polysome?

<p>Lincomycin (D)</p> Signup and view all the answers

Which antibiotic distorts the phospholipid bilayer by altering the semi-permeability?

<p>Polymyxin (B)</p> Signup and view all the answers

Which antibiotic causes anemia as a side effect?

<p>Tetracycline (D)</p> Signup and view all the answers

Which antibiotic binds with sterols in the cell membranes, especially for mycoplasmas?

<p>Nystatin (C)</p> Signup and view all the answers

Which antibiotic causes decolorization of teeth as a side effect?

<p>Chloramphenicol (C)</p> Signup and view all the answers

Which antibiotic binds to DNA, prevents replication and transcription?

<p>Actinomycin (B)</p> Signup and view all the answers

Which antibiotic causes hearing problems as a side effect?

<p>Streptomycin (A)</p> Signup and view all the answers

Which antibiotic inhibits peptide bond formation and causes dissociation of polysome?

<p>Lincomycin (C)</p> Signup and view all the answers

Which antibiotic prevents DNA gyrase from uncoiling DNA?

<p>Nalidixic acid (B)</p> Signup and view all the answers

Which antibiotic prevents tRNA, amino acids, and ribosomal binding?

<p>Tetracycline (B)</p> Signup and view all the answers

Which antibiotic inhibits RNA polymerase, therefore inhibits DNA replication and transcription?

<p>Rifampicin (C)</p> Signup and view all the answers

Flashcards

What are antibiotics?

Chemicals produced by microorganisms that kill or inhibit the growth of other microorganisms.

Antibiotic Producers (Excluding)

Viruses are not producers of antibiotics; bacteria and fungi are.

Antibiotic Action Modes

Inhibition of cell wall synthesis, protein synthesis, cell membrane function, and DNA/RNA synthesis.

Vancomycin's Action

It inhibits cell wall synthesis by binding to the last D-alanine molecules.

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Mode of Action of Penicillin

It inhibits cell wall synthesis by blocking transpeptidation.

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Clindamycin's Target

It prevents peptide bond formation, effective against obligate anaerobic bacteria.

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Streptomycin's Function

It prevents the initiation of protein synthesis.

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Vancomycin: Blocking Enzymes

It binds to the last D-alanine, stopping its removal by blocking enzymes.

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How Erythromycin Works

It prevents the translocation process during protein synthesis.

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Actinomycin's Impact

It binds to DNA, preventing replication and transcription.

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Polymyxin's Effect

It distorts the phospholipid bilayer, altering cell permeability.

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Lincomycin's Disruptive Action

It inhibits peptide bond formation and causes dissociation of polysomes.

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Tetracycline's Side Effect

It can cause anemia as a side effect.

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Nystatin's Target

It binds with sterols in cell membranes, especially in mycoplasmas.

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Side Effect: Chloramphenicol

Can cause decolorization of teeth.

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Purpose of Nalidixic acid

Inhibits the enzyme DNA gyrase preventing uncoiling.

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Effect of Tetracycline

Prevents tRNA, amino acids, and ribosomal binding.

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Effect of Rifampicin

Inhibits RNA polymerase, therefore inhibits DNA replication and transcription

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Streptomycin's Side effect

Hearing Problems

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