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Questions and Answers
Antibiotics that affect protein synthesis target the differences between prokaryotic and eukaryotic cells.
Antibiotics that affect protein synthesis target the differences between prokaryotic and eukaryotic cells.
True (A)
Which antibiotics inhibit protein synthesis by preventing attachment to the 30S ribosomal subunit?
Which antibiotics inhibit protein synthesis by preventing attachment to the 30S ribosomal subunit?
Aminoglycoside antibiotics
What is Erythromycin a member of?
What is Erythromycin a member of?
macrolide group of antibiotics
Rifamycins affect mRNA production by inhibiting the ____________.
Rifamycins affect mRNA production by inhibiting the ____________.
What does MRSA stand for?
What does MRSA stand for?
Vancomycin is effective against all antibiotic-resistant infections.
Vancomycin is effective against all antibiotic-resistant infections.
How do some bacteria eliminate the effectiveness of antibiotics?
How do some bacteria eliminate the effectiveness of antibiotics?
Acquired resistance through bacterial conjugation is described as intrinsic resistance.
Acquired resistance through bacterial conjugation is described as intrinsic resistance.
Where are genes for enzymes that inactivate antibiotics usually carried?
Where are genes for enzymes that inactivate antibiotics usually carried?
What is the term for the lowest concentration of an antibiotic that prevents the growth of a microorganism?
What is the term for the lowest concentration of an antibiotic that prevents the growth of a microorganism?
In the disc diffusion method, antibiotics diffuse inwards from the center of the disc.
In the disc diffusion method, antibiotics diffuse inwards from the center of the disc.
What limits the usefulness of polyene antibiotics in fungal infections?
What limits the usefulness of polyene antibiotics in fungal infections?
What does acyclovir inhibit?
What does acyclovir inhibit?
Acyclovir has been used in the treatment of AIDS.
Acyclovir has been used in the treatment of AIDS.
Following Fleming's discovery of penicillin, ____________ were largely responsible for developing it.
Following Fleming's discovery of penicillin, ____________ were largely responsible for developing it.
It is essential for an antimicrobial agent to have _______________ to avoid affecting host cells.
It is essential for an antimicrobial agent to have _______________ to avoid affecting host cells.
Penicillins and cephalosporins both belong to the _____________ group of antibiotics.
Penicillins and cephalosporins both belong to the _____________ group of antibiotics.
They bind to the _____________ enzyme, preventing the extension of the peptide chain during protein synthesis.
They bind to the _____________ enzyme, preventing the extension of the peptide chain during protein synthesis.
____________ penicillins such as ampicillin have been developed to overcome some of the problems inherent in naturally occurring forms.
____________ penicillins such as ampicillin have been developed to overcome some of the problems inherent in naturally occurring forms.
____________ was the first antibiotic to show effectiveness against Gram-negative bacteria.
____________ was the first antibiotic to show effectiveness against Gram-negative bacteria.
____________ have a particularly broad range of specificity and act by preventing extension of the peptide chain during protein synthesis.
____________ have a particularly broad range of specificity and act by preventing extension of the peptide chain during protein synthesis.
Antibiotics that affect protein synthesis target the differences between prokaryotic and eukaryotic ______________.
Antibiotics that affect protein synthesis target the differences between prokaryotic and eukaryotic ______________.
Aminoglycoside antibiotics inhibit protein synthesis by preventing attachment of the _____________ subunit.
Aminoglycoside antibiotics inhibit protein synthesis by preventing attachment of the _____________ subunit.
What is another member of the macrolide group of antibiotics often used?
What is another member of the macrolide group of antibiotics often used?
Flashcards
Antibiotic Protein Synthesis Target
Antibiotic Protein Synthesis Target
Antibiotics that affect protein synthesis exploit the differences in prokaryotic and eukaryotic cellular structures.
Aminoglycoside Mechanism
Aminoglycoside Mechanism
Aminoglycoside antibiotics hinder protein synthesis by preventing the 30S ribosomal subunit from properly binding.
Macrolide Example
Macrolide Example
Erythromycin is a macrolide antibiotic sometimes used to treat bacterial infections in children.
Rifamycin Target
Rifamycin Target
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MRSA and Nosocomial Infections
MRSA and Nosocomial Infections
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Antibiotic Resistance (Vancomycin)
Antibiotic Resistance (Vancomycin)
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Efflux Pumps
Efflux Pumps
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Acquired Resistance
Acquired Resistance
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Antibiotic Inactivating Enzymes
Antibiotic Inactivating Enzymes
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Minimum Inhibitory Concentration (MIC)
Minimum Inhibitory Concentration (MIC)
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Study Notes
Antibiotics and Antimicrobial Agents
- Antibiotics affect protein synthesis, targeting differences between prokaryotic and eukaryotic cells
- Aminoglycoside antibiotics block protein synthesis by preventing attachment to the ribosome's subunit
- Rifamycins affect mRNA production by inhibiting the enzyme RNA polymerase
- MRSA is a major antibiotic-resistant organism frequently found in hospitals
- Some bacteria pump antibiotics out of the cell before they can act
- Antibiotic resistance can be acquired through bacterial conjugation
- Genes for enzymes that inactivate antibiotics are often carried on plasmids
- The lowest concentration of an antibiotic that prevents growth is the minimum inhibitory concentration (MIC)
- In the disk diffusion method, the antibiotic diffuses outward to affect bacteria
- Polyene antibiotics are less effective against human cells due to their low efficacy
- Acyclovir is an antiviral agent that inhibits viral replication
Antibiotic Discovery and Use
- Penicillin is one of the first antibiotics to treat Gram-negative bacteria
- Penicillins and Cephalosporins inhibit the formation of peptidoglycans in bacterial cell walls
- Phage therapy is an alternative approach to antibiotic treatments
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Description
Test your knowledge on the mechanisms and effects of antibiotics and antimicrobial agents. This quiz covers topics such as protein synthesis inhibition, antibiotic resistance, and the various types of antibiotics and their uses. Perfect for students in microbiology or pharmacology courses.
