Antigen Receptors and Activation of T and B Cells
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Questions and Answers

What is the role of T cell receptor (TCR) and B cell receptor (BCR) on T and B cells, respectively?

  • They produce antibodies against antigens
  • They help in antigen presentation
  • They assist in immune response initiation
  • They carry antigen receptors on their surface (correct)
  • Why does random rearrangement of genes for the variable region of receptor molecules occur?

  • To increase the rate of antigen uptake
  • To produce receptors with a wide range of antigen binding sites (correct)
  • To induce apoptosis in lymphocytes
  • To decrease the specificity of T and B cells
  • How is an immune response initiated in T cells?

  • By exposure to cytokines
  • By contact with antigen presenting cells (APCs) (correct)
  • By interaction with B cells only
  • By direct activation through antigens
  • What happens when an antigen is taken up by an antigen presenting cell (APC)?

    <p>It is broken down into short peptides</p> Signup and view all the answers

    In T cells, which type of MHC-peptide complex induces a T helper cell (TH) response?

    <p>Class II MHC-peptide complex</p> Signup and view all the answers

    What is the outcome of an antigenic peptide being presented to T cells via MHC class II molecules?

    <p>Induction of a T helper cell response</p> Signup and view all the answers

    When is activation of B or cytotoxic T cells mediated by a variety of interleukins?

    <p>When B cell receptors bind to the antigen</p> Signup and view all the answers

    How do cytotoxic T cells recognize antigens presented on an infected cell's membrane?

    <p>By binding to class I MHC proteins</p> Signup and view all the answers

    What is required for a TC response to be mounted when antigen is synthesized within a body cell?

    <p>Activation of TH cells</p> Signup and view all the answers

    How do B lymphocytes recognize unprocessed antigens?

    <p>Recognition by the BCR (surface immunoglobulin, sIg)</p> Signup and view all the answers

    What happens when antibodies bind to viral surface antigens according to the text?

    <p>Activation of complement</p> Signup and view all the answers

    Which mechanism leads to the destruction of abnormal cells through apoptosis?

    <p>Cell-mediated cytotoxicity by cytotoxic T cells and NK cells</p> Signup and view all the answers

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