Antigen Processing and Presentation Pathways
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Questions and Answers

What is the primary function of Class I MHC antigens?

  • To present endogenous antigens to CD8 cells (correct)
  • To bind with antibodies
  • To facilitate humoral immune response
  • To activate CD4 cells

What is the approximate length of peptides bound to the MHC I groove?

  • 5-7 amino acids
  • 20-25 amino acids
  • 15-20 amino acids
  • 8-10 amino acids (correct)

What is the function of the β2-microglobulin molecule in MHC I?

  • To maintain proper conformation of MHC I molecules (correct)
  • To interact with CD8 cells
  • To bind peptides
  • To recognize endogenous antigens

What is the primary function of the α3 domain of MHC I?

<p>To serve as a binding site for CD8 (C)</p> Signup and view all the answers

What is the primary function of MHC class I molecules?

<p>To present endogenous antigens to CD8 cells (D)</p> Signup and view all the answers

Which type of cells typically express MHC class II molecules?

<p>Professional antigen presenting cells (A)</p> Signup and view all the answers

What is the nature of the transmembrane segment of MHC I molecules?

<p>Hydrophobic (C)</p> Signup and view all the answers

What is the primary function of the α1 and α2 domains of MHC I?

<p>To form a highly polymorphic peptide binding cleft (C)</p> Signup and view all the answers

Which type of cells can express MHC class I molecules?

<p>Only nucleated cells (A)</p> Signup and view all the answers

What is the homology between α3 and β2 microglobulin?

<p>Homology with immunoglobulin constant regions (C)</p> Signup and view all the answers

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