Podcast
Questions and Answers
What is the main role of Follicular Helper T cells (T FH cells)?
What is the main role of Follicular Helper T cells (T FH cells)?
- Producing ROS
- Activating macrophages
- Killing infected cells
- Activating B cells (correct)
Which subset of T cells stays in the lymph nodes to fight infection and does not egress to the site of infection?
Which subset of T cells stays in the lymph nodes to fight infection and does not egress to the site of infection?
- CTLs
- Follicular Helper T cells (correct)
- Th1 cells
- TH2 cells
What is responsible for directing T-cell differentiation into distinct effector cell types?
What is responsible for directing T-cell differentiation into distinct effector cell types?
- Signal 1
- IL-2
- Signal 2
- Signal 3 (correct)
Which type of T cells differentiate into cytotoxic T lymphocytes (CTLs)?
Which type of T cells differentiate into cytotoxic T lymphocytes (CTLs)?
What is the main function of Regulatory T cells?
What is the main function of Regulatory T cells?
What do activated effector T cells need to find their match and kill infected cells?
What do activated effector T cells need to find their match and kill infected cells?
What molecule plays a role in restoring epithelial integrity after an infection is cleared?
What molecule plays a role in restoring epithelial integrity after an infection is cleared?
What is the role of L-selectin in the immune response?
What is the role of L-selectin in the immune response?
Which molecule binds to receptors on endothelial cells near inflamed tissue?
Which molecule binds to receptors on endothelial cells near inflamed tissue?
What determines the fate of T cells according to the text?
What determines the fate of T cells according to the text?
Which type of pathogens induce a Type 1 response in the immune system?
Which type of pathogens induce a Type 1 response in the immune system?
How do polarizing cytokines affect T cells?
How do polarizing cytokines affect T cells?
Which proteins act as transcription factors after being phosphorylated by cytokine signaling?
Which proteins act as transcription factors after being phosphorylated by cytokine signaling?
What is the function of master transcriptional regulators in T cells?
What is the function of master transcriptional regulators in T cells?
Which type of immunity do extracellular pathogens like worms induce?
Which type of immunity do extracellular pathogens like worms induce?
How do polarizing cytokines guide T cells toward different effector fates?
How do polarizing cytokines guide T cells toward different effector fates?
Which type of cytokines are responsible for signaling the differentiation of T helper cell subsets?
Which type of cytokines are responsible for signaling the differentiation of T helper cell subsets?
How does the expression of new transcription factors affect T cell subtype activity?
How does the expression of new transcription factors affect T cell subtype activity?
Which molecules determine the function of different T cells by regulating gene expression?
Which molecules determine the function of different T cells by regulating gene expression?
Which type of immunity is induced by extracellular pathogens like worms?
Which type of immunity is induced by extracellular pathogens like worms?
What is the main function of APCs in the immune response related to effector T cells?
What is the main function of APCs in the immune response related to effector T cells?
What is the function of L-selectin in the immune response?
What is the function of L-selectin in the immune response?
What induces the expression of transcription factors like GATA-3 and T-Bet in T cells?
What induces the expression of transcription factors like GATA-3 and T-Bet in T cells?
What is the main function of L-selectin and VLA-4 in the immune response?
What is the main function of L-selectin and VLA-4 in the immune response?
Which subset of T cells remains in the lymph nodes to combat infections without egressing to the site of infection?
Which subset of T cells remains in the lymph nodes to combat infections without egressing to the site of infection?
What is the primary role of CTLA4 in the immune system?
What is the primary role of CTLA4 in the immune system?
Which molecule is not required for activated effector T cells to find their match and kill infected cells?
Which molecule is not required for activated effector T cells to find their match and kill infected cells?
What is the primary function of Regulatory T cells in adaptive immunity?
What is the primary function of Regulatory T cells in adaptive immunity?
Which cytokines are responsible for promoting Th1 cell-mediated immunity?
Which cytokines are responsible for promoting Th1 cell-mediated immunity?
What triggers the differentiation of Naïve CD8+ T cells into cytotoxic T lymphocytes?
What triggers the differentiation of Naïve CD8+ T cells into cytotoxic T lymphocytes?
'Signal 3' in T cell activation is primarily responsible for directing what process?
'Signal 3' in T cell activation is primarily responsible for directing what process?
'Efferent lymphatics' play a role in transporting immune cells from lymph nodes to where in the body?
'Efferent lymphatics' play a role in transporting immune cells from lymph nodes to where in the body?
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