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Questions and Answers
What is the main role of Follicular Helper T cells (T FH cells)?
What is the main role of Follicular Helper T cells (T FH cells)?
Which subset of T cells stays in the lymph nodes to fight infection and does not egress to the site of infection?
Which subset of T cells stays in the lymph nodes to fight infection and does not egress to the site of infection?
What is responsible for directing T-cell differentiation into distinct effector cell types?
What is responsible for directing T-cell differentiation into distinct effector cell types?
Which type of T cells differentiate into cytotoxic T lymphocytes (CTLs)?
Which type of T cells differentiate into cytotoxic T lymphocytes (CTLs)?
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What is the main function of Regulatory T cells?
What is the main function of Regulatory T cells?
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What do activated effector T cells need to find their match and kill infected cells?
What do activated effector T cells need to find their match and kill infected cells?
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What molecule plays a role in restoring epithelial integrity after an infection is cleared?
What molecule plays a role in restoring epithelial integrity after an infection is cleared?
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What is the role of L-selectin in the immune response?
What is the role of L-selectin in the immune response?
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Which molecule binds to receptors on endothelial cells near inflamed tissue?
Which molecule binds to receptors on endothelial cells near inflamed tissue?
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What determines the fate of T cells according to the text?
What determines the fate of T cells according to the text?
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Which type of pathogens induce a Type 1 response in the immune system?
Which type of pathogens induce a Type 1 response in the immune system?
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How do polarizing cytokines affect T cells?
How do polarizing cytokines affect T cells?
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Which proteins act as transcription factors after being phosphorylated by cytokine signaling?
Which proteins act as transcription factors after being phosphorylated by cytokine signaling?
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What is the function of master transcriptional regulators in T cells?
What is the function of master transcriptional regulators in T cells?
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Which type of immunity do extracellular pathogens like worms induce?
Which type of immunity do extracellular pathogens like worms induce?
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How do polarizing cytokines guide T cells toward different effector fates?
How do polarizing cytokines guide T cells toward different effector fates?
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Which type of cytokines are responsible for signaling the differentiation of T helper cell subsets?
Which type of cytokines are responsible for signaling the differentiation of T helper cell subsets?
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How does the expression of new transcription factors affect T cell subtype activity?
How does the expression of new transcription factors affect T cell subtype activity?
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Which molecules determine the function of different T cells by regulating gene expression?
Which molecules determine the function of different T cells by regulating gene expression?
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Which type of immunity is induced by extracellular pathogens like worms?
Which type of immunity is induced by extracellular pathogens like worms?
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What is the main function of APCs in the immune response related to effector T cells?
What is the main function of APCs in the immune response related to effector T cells?
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What is the function of L-selectin in the immune response?
What is the function of L-selectin in the immune response?
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What induces the expression of transcription factors like GATA-3 and T-Bet in T cells?
What induces the expression of transcription factors like GATA-3 and T-Bet in T cells?
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What is the main function of L-selectin and VLA-4 in the immune response?
What is the main function of L-selectin and VLA-4 in the immune response?
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Which subset of T cells remains in the lymph nodes to combat infections without egressing to the site of infection?
Which subset of T cells remains in the lymph nodes to combat infections without egressing to the site of infection?
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What is the primary role of CTLA4 in the immune system?
What is the primary role of CTLA4 in the immune system?
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Which molecule is not required for activated effector T cells to find their match and kill infected cells?
Which molecule is not required for activated effector T cells to find their match and kill infected cells?
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What is the primary function of Regulatory T cells in adaptive immunity?
What is the primary function of Regulatory T cells in adaptive immunity?
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Which cytokines are responsible for promoting Th1 cell-mediated immunity?
Which cytokines are responsible for promoting Th1 cell-mediated immunity?
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What triggers the differentiation of Naïve CD8+ T cells into cytotoxic T lymphocytes?
What triggers the differentiation of Naïve CD8+ T cells into cytotoxic T lymphocytes?
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'Signal 3' in T cell activation is primarily responsible for directing what process?
'Signal 3' in T cell activation is primarily responsible for directing what process?
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'Efferent lymphatics' play a role in transporting immune cells from lymph nodes to where in the body?
'Efferent lymphatics' play a role in transporting immune cells from lymph nodes to where in the body?
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