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Antigen-Antibody Reactions

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Questions and Answers

What is required for the formation of a visible precipitate in antigen-antibody reactions?

Monovalent antibody and bivalent or polyvalent antigen

Monovalent antibody and monovalent antigen

Bivalent antibody and bivalent or polyvalent antigen (correct)

Bivalent antibody and monovalent antigen

What are antibodies called when they aggregate soluble antigens?

Agglutinins

Opsonins

Precipitins (correct)

Neutralizing antibodies

What is the purpose of centrifuging the tubes in a quantitative precipitation reaction?

To separate the antibody and antigen

To pellet the precipitate (correct)

To mix the antibody and antigen

To measure the amount of antigen

What does a precipitin curve measure?

<p>Amount of precipitate against increasing antigen concentrations</p> Signup and view all the answers

What type of antigen is required for the formation of an Ag-Ab lattice?

<p>Bivalent or polyvalent antigen</p> Signup and view all the answers

Study Notes

Antigen-Antibody Reactions

A visible precipitate forms when antigen-antibody complexes aggregate to a size that can be seen, requiring a sufficient concentration of both antigen and antibody.
Antibodies that aggregate soluble antigens are called precipitins.

Quantitative Precipitation Reaction

Centrifuging the tubes in a quantitative precipitation reaction separates the precipitate from the supernatant, allowing for measurement of the precipitate.

Precipitin Curve

A precipitin curve measures the amount of precipitate formed as a function of antigen concentration, providing a quantitative representation of the antigen-antibody reaction.

Antigen Requirements

For the formation of an Ag-Ab lattice, a multivalent antigen (having multiple epitopes) is required, allowing for the cross-linking of antibodies and subsequent precipitation.

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Description

Test your knowledge of antigen-antibody reactions with this clinical immunity quiz. Explore the concepts of precipitins and the formation of visible precipitates. Ideal for medical students and professionals seeking to deepen their understanding of immunology.