18 Questions
Which class of antifungal drugs inhibits squalene epoxidase, an essential step in ergosterol synthesis?
Allylamines
Which antifungal drug class is considered less toxic than the Imidazole azoles?
Triazoles
Which antifungal drug class inhibits the synthesis of $ß(1,3)$-glucan, a major component of the fungal cell wall?
Echinocandins
Which antifungal drug is used to treat both cutaneous and vaginal candidiasis?
Fluconazole
Which antifungal drug class has a broad spectrum of activity, including treatment of chromoblastomycosis, histoplasmosis, and coccidioidomycosis?
Itraconazole
Which antifungal drug class is used for the topical treatment of dermatophyte infections like tinea pedis and tinea corporis?
Allylamines
Which class of antifungal drugs inhibits ergosterol synthesis by inhibiting the enzyme 14-alpha-demethylase?
Azoles
Which type of antifungal drug disrupts spindle formation, thus preventing mitosis?
Griseofulvin
Which antifungal drug class targets the fungal cell wall by inhibiting $b-(1,3)$-glucan synthase?
Echinocandins
Which antifungal drug class is chemically synthesized and inhibits the fungal enzyme lanosterol 14-alpha-demethylase?
Triazoles
Which antifungal drug is effective against candidiasis and cryptococcosis, and is often used synergistically with amphotericin B?
Flucytosine
Which class of antifungal drugs disrupts the fungal cell membrane by binding to ergosterol?
Polyenes
Which class of antifungal drugs targets the fungal cell wall by inhibiting the enzyme $eta$-1,3-D-glucan synthase?
Echinocandins
Which antifungal drug class inhibits the enzyme squalene epoxidase, leading to the accumulation of toxic sterols in the fungal cell membrane?
Allylamines
Which antifungal drug class inhibits the biosynthesis of ergosterol, a key component of the fungal cell membrane?
Azoles
Which class of antifungal drugs is derived from a natural product and interferes with microtubule formation, preventing fungal cell division?
Griseofulvin
Which antifungal drug class inhibits fungal cell division by interfering with microtubule function?
Griseofulvin
Which antifungal drug class targets the fungal cell membrane by inhibiting the enzyme squalene epoxidase, a key step in ergosterol biosynthesis?
Allylamines
Learn about antifungal drug Griseofulvin produced by Penicillium species, which disrupts spindle formation to prevent fungal mitosis. Discover how the drug, taken orally for months, concentrates into the skin's dead keratinized layers, inhibiting fungal growth against ringworm caused by specific fungal species.
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