Antiepileptic Drugs
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Questions and Answers

Which antiepileptic drug is associated with gingival hyperplasia?

  • Phenytoin (correct)
  • Valproic acid
  • Topamax
  • Carbamazepine

Which antiepileptic drug is nicknamed 'dopamax' or 'stupimax' due to its association with word finding difficulties and cognitive slowing?

  • Carbamazepine
  • Topamax (correct)
  • Phenytoin
  • Valproic acid

Which antiepileptic drug is known as the 'divorce drug' due to its association with behavioral symptoms such as agitation, lability, hostility, and depression?

  • Levetiracetam (correct)
  • Carbamazepine
  • Valproic acid
  • Phenytoin

Which antiepileptic drug is associated with the most drug interactions?

<p>Carbamazepine (C)</p> Signup and view all the answers

Which antiepileptic drug should not be used in child-bearing aged women due to its teratogenic potential?

<p>Valproic acid (C)</p> Signup and view all the answers

Which antiepileptic drug is associated with word finding difficulties and cognitive slowing?

<p>Topamax (C)</p> Signup and view all the answers

Which antiepileptic drug is used for chronic neuropathic pain and causes weight gain?

<p>Pregabalin (C)</p> Signup and view all the answers

Which antiepileptic drug has the fewest drug interactions?

<p>Pregabalin (C)</p> Signup and view all the answers

Which antiepileptic drug is associated with progressive and permanent bilateral peripheral visual loss?

<p>Vigabatrin (D)</p> Signup and view all the answers

Which antiepileptic drug is associated with PCOS, tremor, pancreatitis, hepatotoxicity, teratogenicity, and thrombocytopenia?

<p>Valproic acid (B)</p> Signup and view all the answers

Flashcards

Gingival hyperplasia drug

Phenytoin is an antiepileptic drug that can cause the gums to swell.

'Dopamax/Stupimax' drug

Topamax is associated with cognitive slowing and trouble recalling words.

'Divorce drug'

Levetiracetam is linked to mood changes, agitation, hostility, and depression.

Antiepileptic with the most interactions

Carbamazepine has many interactions with other drugs.

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Antiepileptic avoided in women of bearing age

Valproic acid can cause birth defects.

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Antiepileptic that affects cognition

Topamax makes it difficult to recall words and slows thinking.

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Antiepileptic for neuropathic pain

Pregabalin is used for nerve pain and can cause weight gain.

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Antiepileptic with the fewest interactions

Pregabalin has very few interactions with other drugs.

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Antiepileptic causing vision loss

Vigabatrin can cause permanent vision loss.

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Antiepileptic linked to PCOS etc.

Valproic acid is associated with many endocrine and metabolic issues.

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Study Notes

Antiepileptic Drug Associations

  • Gingival Hyperplasia: Phenytoin is known for causing gingival hyperplasia, a condition where gums grow excessively.
  • Dopamax/Stupimax: Topiramate is nicknamed 'dopamax' or 'stupimax' due to cognitive side effects including word-finding difficulties and cognitive slowing.
  • Divorce Drug: Lamotrigine is referred to as the 'divorce drug' linked with behavioral symptoms such as agitation, emotional lability, hostility, and depression.
  • Most Drug Interactions: Carbamazepine is recognized for having the most drug interactions among antiepileptic medications.
  • Teratogenic Potential: Valproate should not be used in women of child-bearing age because of its high teratogenicity risk, which can lead to fetal developmental issues.
  • Cognitive Slowing: Topiramate is again associated with cognitive slowing and difficulties in word finding.
  • Chronic Neuropathic Pain: Gabapentin is used for chronic neuropathic pain and is known to cause weight gain as a side effect.
  • Fewest Drug Interactions: Levetiracetam is notable for having the fewest drug interactions, making it a safer choice in polypharmacy.
  • Progressive Visual Loss: Vigabatrin is linked to progressive and permanent bilateral peripheral visual loss, a serious side effect that requires monitoring.
  • PCOS and Other Risks: Valproate is associated with a range of risks including PolyCystic Ovary Syndrome (PCOS), tremors, pancreatitis, hepatotoxicity, teratogenicity, and thrombocytopenia.

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Test your knowledge on antiepileptic drugs and their side effects, including gingival hyperplasia, drug interactions, teratogenic potential, and cognitive difficulties.

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