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Questions and Answers
Which of these medications is classified as an indirect-acting cholinergic drug?
Which of these medications is classified as an indirect-acting cholinergic drug?
What is the primary mechanism of action for Oxybutynin?
What is the primary mechanism of action for Oxybutynin?
Which of the following is a contraindication for Memantine?
Which of the following is a contraindication for Memantine?
What is a common adverse effect of Pyridostigmine?
What is a common adverse effect of Pyridostigmine?
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Which medication is indicated for the treatment of overactive bladder (OAB)?
Which medication is indicated for the treatment of overactive bladder (OAB)?
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What nursing implication is important to consider when administering Pyridostigmine?
What nursing implication is important to consider when administering Pyridostigmine?
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Which of the following is NOT a contraindication for Oxybutynin?
Which of the following is NOT a contraindication for Oxybutynin?
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Which of the following medications is used to treat the symptoms of myasthenia gravis?
Which of the following medications is used to treat the symptoms of myasthenia gravis?
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Which of these conditions would be a contraindication for administering Dicyclomine?
Which of these conditions would be a contraindication for administering Dicyclomine?
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What is the mechanism of action of Dicyclomine?
What is the mechanism of action of Dicyclomine?
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Which of the following nursing implications would NOT be appropriate when administering Dicyclomine?
Which of the following nursing implications would NOT be appropriate when administering Dicyclomine?
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A patient is taking Dicyclomine for irritable bowel syndrome. Which of these would be most important to include in patient education?
A patient is taking Dicyclomine for irritable bowel syndrome. Which of these would be most important to include in patient education?
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According to the provided information, what is the recommended dosage of Dicyclomine?
According to the provided information, what is the recommended dosage of Dicyclomine?
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Which ethical principle emphasizes the nurse's obligation to avoid causing harm to the patient?
Which ethical principle emphasizes the nurse's obligation to avoid causing harm to the patient?
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Which of the following is NOT a contraindication for administering Dicyclomine?
Which of the following is NOT a contraindication for administering Dicyclomine?
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What is the primary benefit of administering Dicyclomine to a patient with irritable bowel syndrome?
What is the primary benefit of administering Dicyclomine to a patient with irritable bowel syndrome?
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Which of the following is a potential adverse effect of taking Mirabegron (Myrbetriq)?
Which of the following is a potential adverse effect of taking Mirabegron (Myrbetriq)?
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What is the primary mechanism of action of Tamsulosin (Flomax)?
What is the primary mechanism of action of Tamsulosin (Flomax)?
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Which of the following contraindications applies to the use of Epinephrine?
Which of the following contraindications applies to the use of Epinephrine?
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Which medication is classified as a nonselective beta-blocker?
Which medication is classified as a nonselective beta-blocker?
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What is the primary indication for using Dopamine (Inotropen) at a low dose?
What is the primary indication for using Dopamine (Inotropen) at a low dose?
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Which of the following is NOT a potential adverse effect of Epinephrine?
Which of the following is NOT a potential adverse effect of Epinephrine?
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Which of the following is a contraindication for the use of Sotalol (Betapace)?
Which of the following is a contraindication for the use of Sotalol (Betapace)?
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What is the appropriate nursing implication for administering Metoprolol (Lopressor) intravenously (IV)?
What is the appropriate nursing implication for administering Metoprolol (Lopressor) intravenously (IV)?
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Which of the following medications is NOT a sympathomimetic drug?
Which of the following medications is NOT a sympathomimetic drug?
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What is a potential adverse effect associated with Tamsulosin (Flomax) use?
What is a potential adverse effect associated with Tamsulosin (Flomax) use?
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Which of the following statements is TRUE regarding Mirabegron (Myrbetriq)?
Which of the following statements is TRUE regarding Mirabegron (Myrbetriq)?
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Which of the following nursing implications is MOST important when administering Dopamine (Inotropen)?
Which of the following nursing implications is MOST important when administering Dopamine (Inotropen)?
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Which of the following is NOT a common indication for using Epinephrine?
Which of the following is NOT a common indication for using Epinephrine?
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What is the primary mechanism of action of Sotalol (Betapace)?
What is the primary mechanism of action of Sotalol (Betapace)?
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Which of the following medications is classified as a beta 1 adrenergic agonist?
Which of the following medications is classified as a beta 1 adrenergic agonist?
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Which of the following medications, when used long-term, can cause irreversible tardive dyskinesia?
Which of the following medications, when used long-term, can cause irreversible tardive dyskinesia?
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Which antiemetic medication is classified as an antihistamine (H1 receptor blocker)?
Which antiemetic medication is classified as an antihistamine (H1 receptor blocker)?
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What is the preferred route of administration for promethazine (Phenergan)?
What is the preferred route of administration for promethazine (Phenergan)?
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Which drug class does Ondansetron (Zofran) belong to?
Which drug class does Ondansetron (Zofran) belong to?
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Which of the following medications is contraindicated in patients with glaucoma?
Which of the following medications is contraindicated in patients with glaucoma?
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Which of the following medications is classified as a prokinetic drug?
Which of the following medications is classified as a prokinetic drug?
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What is the mechanism of action of promethazine (Phenergan)?
What is the mechanism of action of promethazine (Phenergan)?
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Which of these medications is contraindicated for breastfeeding mothers?
Which of these medications is contraindicated for breastfeeding mothers?
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Which of the following is a potential adverse effect of promethazine (Phenergan)?
Which of the following is a potential adverse effect of promethazine (Phenergan)?
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What is the primary indication for scopolamine (Transderm-Scop) medication?
What is the primary indication for scopolamine (Transderm-Scop) medication?
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What is the contraindication for promethazine (Phenergan) in children less than 2 years old?
What is the contraindication for promethazine (Phenergan) in children less than 2 years old?
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What is the mechanism of action of ondansetron (Zofran)?
What is the mechanism of action of ondansetron (Zofran)?
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When administering promethazine (Phenergan) intravenously, which of the following is important?
When administering promethazine (Phenergan) intravenously, which of the following is important?
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What is the primary mechanism of action of meclizine (Antivert)?
What is the primary mechanism of action of meclizine (Antivert)?
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Which of these medications should be diluted in at least 10 ml of fluid before IV administration?
Which of these medications should be diluted in at least 10 ml of fluid before IV administration?
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Which of these medications is available as a transdermal patch?
Which of these medications is available as a transdermal patch?
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Flashcards
Memantine
Memantine
A drug that blocks stimulation of certain receptors to reduce cognitive symptoms in dementia.
Contraindications for Memantine
Contraindications for Memantine
Conditions where Memantine should not be used, like drug allergies.
Adverse Effects of Memantine
Adverse Effects of Memantine
Uncommon side effects include confusion and GI upset.
Pyridostigmine
Pyridostigmine
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Mechanism of Action of Pyridostigmine
Mechanism of Action of Pyridostigmine
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Oxybutynin
Oxybutynin
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Adverse Effects of Oxybutynin
Adverse Effects of Oxybutynin
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Patient Education for Oxybutynin
Patient Education for Oxybutynin
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Dicyclomine
Dicyclomine
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Anticholinergic effects
Anticholinergic effects
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Contraindications
Contraindications
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Patient Education
Patient Education
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Veracity
Veracity
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Beneficence
Beneficence
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Duty
Duty
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Justice
Justice
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Antiemetics
Antiemetics
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Chemoreceptor Trigger Zone (CTZ)
Chemoreceptor Trigger Zone (CTZ)
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Metoclopramide (Reglan)
Metoclopramide (Reglan)
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Contraindications of Metoclopramide
Contraindications of Metoclopramide
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Tardive Dyskinesia
Tardive Dyskinesia
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Ondansetron (Zofran)
Ondansetron (Zofran)
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Antihistamine
Antihistamine
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Meclizine (Antivert)
Meclizine (Antivert)
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Promethazine (Phenergan)
Promethazine (Phenergan)
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Contraindications of Promethazine
Contraindications of Promethazine
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Scopolamine
Scopolamine
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Adverse Effects of Scopolamine
Adverse Effects of Scopolamine
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Assessment for Allergies
Assessment for Allergies
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N/V in Pregnancy
N/V in Pregnancy
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Adrenergic Agonists
Adrenergic Agonists
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Alpha 1 Receptors
Alpha 1 Receptors
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Alpha 2 Receptors
Alpha 2 Receptors
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Beta 1 Receptors
Beta 1 Receptors
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Beta 2 Receptors
Beta 2 Receptors
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Dopamine
Dopamine
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Epinephrine (Epi-Pen)
Epinephrine (Epi-Pen)
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Adverse Effects of Adrenergics
Adverse Effects of Adrenergics
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Mirabegron (Myrbetriq)
Mirabegron (Myrbetriq)
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Tamsulosin (Flomax)
Tamsulosin (Flomax)
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Sotalol (Betapace)
Sotalol (Betapace)
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Metoprolol (Lopressor)
Metoprolol (Lopressor)
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Nursing Implications of Adrenergics
Nursing Implications of Adrenergics
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Contraindications of Epinephrine
Contraindications of Epinephrine
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Mechanism of Action of Beta Blockers
Mechanism of Action of Beta Blockers
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Study Notes
Antiemetic and Antinausea Drugs
- Antiemetics are drugs used to relieve nausea and vomiting.
- Seven categories exist, with different mechanisms of action, primarily by blocking pathways that induce vomiting.
- Chemoreceptor Trigger Zone (CTZ): a brain area responsible for nausea and vomiting sensations.
Metoclopramide (Reglan)
- Class: Prokinetic drug.
- Routes: Oral, Parenteral.
- Indications: Gastroesophageal reflux disease (GERD), delayed gastric emptying, nausea, and vomiting (N/V).
- Mechanism: Blocks dopamine receptors in the CTZ, desensitizing it to impulses from the GI tract. Stimulates GI peristalsis to aid stomach emptying.
- Contraindications: Patients with seizure disorders, pheochromocytoma, breast cancer, and GI obstruction.
- Allergic to procaine or procainamide.
- Adverse Effects: Long-term use can cause irreversible tardive dyskinesia, extrapyramidal symptoms (tremors, muscle contractions, eye spasms, lip smacking, tongue protrusion).
Ondansetron (Zofran)
- Class: Serotonin Blocker.
- Route: Oral, injection.
- Indications: Nausea and vomiting, chemotherapy, and postoperative settings, hyperemesis gravidarum.
- Mechanism: Blocks serotonin receptors in the GI tract, CTZ, and vomiting center (VC).
- Contraindications: Category B medication; concern about cleft palate development during first trimester; known drug allergy.
- Adverse effects: Known drug allergy. This medication is available by prescription only due to potential adverse effects if used incorrectly.
Meclizine (Antivert)
- Class: Antihistamine (H1 receptor blockers).
- Route: Oral.
- Indications: Motion sickness, non-productive cough, allergy symptoms, sedation and vertigo.
- Mechanism: Inhibits the cholinergic stimulation of the vestibular and reticular systems; this prevents nausea and vomiting.
- Contraindications: Shock and lactation.
- Adverse Effects: Drowsiness, fast heartbeat, hives, itching, rash, and headaches.
- Nursing Implications : Assess for drug allergy.
Promethazine (Phenergan)
- Class: Antidopaminergic.
- Routes: Oral, Intramuscular, intravenous.
- Indications: Psychotic disorders, intractable hiccups, relieving hay fever symptoms, allergic conjunctivitis.
- Mechanism: Blocks dopamine receptors in the CTZ.
- Contraindications: Children under two years due to potential for fatal respiratory depression.
- Adverse Effects: Sedation (common) drowsiness, dry mouth, lightheadedness.
- Nursing Implications: Dilute in fluid, administer via large bore vein rather than hand veins, discontinue immediately if pain is experienced.
Scopolamine (Transderm-Scop, Scopace)
- Class: Anticholinergic blocker.
- Route: Transdermal patch.
- Indications: Motion sickness, postoperative nausea/vomiting, pre-surgical use to reduce secretions.
- Mechanism: Blocks acetylcholine receptors in the inner ear labyrinth, preventing nausea-inducing stimuli from reaching the vomiting center.
- Contraindications: Glaucoma, pyloric obstruction, and urinary bladder obstruction.
- Adverse Effects: Blurred vision, confusion, hallucinations, urinary retention.
- Nursing Implications: Caution with glaucoma patients , avoid intra-arterial administration.
Adrenergic Agonists (Sympathomimetics)
- The autonomic nervous system (ANS) and sympathetic nervous system (SNS) play crucial roles.
- Catecholamines (epinephrine, norepinephrine, dopamine) are endogenous.
- Alpha 1 and 2 receptors; Beta 1 and 2 receptors mediate various actions.
- Alpha 1 receptors are postsynaptic. Beta 1 receptors primarily affect the heart.
- Beta 2 receptors are present in the lungs and arteries. Dopaminergic receptors dilate blood vessels in the renal, mesenteric, coronary, and cerebral regions.
- Indications: Cardiovascular (heart failure, shock), respiratory (bronchodilation, nasal congestion), and genitourinary (overactive bladder, benign prostatic hyperplasia).
Epinephrine (Epi-Pen)
- Class: Alpha and Beta adrenergic agonist.
- Indications: Anaphylaxis, bronchospasm, cardiac arrest, asthma.
- Mechanism: Binds to alpha receptors, causing vasoconstriction.
- Contraindications: Hypertension, hypersensitivity, CAD, tachyarrhythmias.
- Adverse effects: Palpitations, tachycardia, anxiety, tremors, hypertension, headache.
- Nursing Implications: Monitor vitals, cardiac rhythm.
Dopamine (Inotropen)
- Class: Beta 1 adrenergic agonist.
- Route: Intravenous.
- Indications: Lower doses dilate blood vessels in the brain, heart, kidneys, and mesentery, increasing blood flow to these areas, and higher doses are used to improve cardiac contractility and output, including cases involving vasoconstriction, dilation pupil, rate heart, arterioles BP, gi motility,
- Contraindications: Hypertension, hypersensitivity.
- Adverse Effects: Palpitations, tachycardia, anxiety, tremors, hypertension, headache.
- Nursing Implications: Monitor vital signs (vitals), cardiac rhythm.
Mirabegron (Myrbetriq)
- Class: GU Adrenergic Agonist (Beta 3 adrenergic).
- Route: Oral.
- Indication: Overactive bladder.
- Mechanism of Action.: Relaxes the detrusor muscle, increasing bladder capacity.
- Contraindications: None reported.
- Adverse Effects: Hypertension, urinary tract infections, headache, nausea, nasopharyngitis, dizziness.
Tamsulosin (Flomax)
- Class: Alpha Adrenergic Blocker.
- Route: Oral.
- Indication: Benign prostatic hyperplasia (BPH), kidney stones, and retention.
- Mechanism: Blocks alpha-adrenergic receptors on the prostate and bladder smooth muscles, relaxing the muscles to improve urinary flow.
- Contraindications: Current use of phosphodiesterase-5 inhibitors (e.g., sildenafil).
- Adverse Effects: Dizziness, orthostatic hypotension, abnormal ejaculation, rhinitis, abdominal pain.
- Nursing Implications: Monitor for dizziness, orthostatic hypotension and urinary retention.
Sotalol (Betapace)
- Class: Nonselective Beta Blocker.
- Route: Oral.
- Indication: Difficult-to-treat dysrhythmias.
- Mechanism of Action: Class III antiarrhythmic properties.
Metoprolol (Lopressor)
- Class: Beta 1 Blocker.
- Routes: Intravenous, oral.
- Indications: Hypertension, angina, heart failure.
- Mechanism: Acts on beta-1 receptors in the heart, reducing catecholamine effects on cardiac function.
- Contraindications: Bronchial asthma, sinus bradycardia, cardiogenic shock.
- Adverse Effects: Torsades de pointes, fatigue, dizziness, bronchospasm, heart failure.
Cholinergic Drugs
- Memantine (Namenda): N-methyl-D-aspartate (NMDA) receptor antagonist used in Alzheimer's dementia treatment.
- Mechanism: Blocks NMDA receptor stimulation, potentially reducing cognitive decline.
- Pyridostigmine (Mestinon): Indirect-acting cholinergic drug enhances acetylcholine effects, used in myasthenia gravis to relieve symptoms and reverse neuromuscular blocking drugs.
Oxybutynin (Ditropan)
- Class: Anticholinergic (muscarinic blocker).
- Route: Oral, transdermal patch (OTC).
- Indications: Overactive bladder (OAB), neurogenic bladder issues.
- Mechanism: Inhibits involuntary contractions of bladder muscles, increasing bladder capacity.
- Contraindications: Allergic response, urinary/gastric retention, uncontrolled angle-closure glaucoma.
- Adverse Effects: Dry mouth (common), constipation, blurred vision, drowsiness, dizziness.
Dicyclomine (Bentyl)
- Class: Synthetic antispasmodic cholinergic blocker.
- Route: Oral.
- Indications: Irritable bowel syndrome, functional gastrointestinal tract disturbances.
- Mechanism of action: Blocks muscarinic receptors in the GI tract, inhibiting smooth muscle contractions.
- Contraindications: Angle-closure glaucoma, GI tract obstruction, myasthenia gravis, paralytic ileus, and toxic megacolon.
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Description
Test your knowledge on antiemetic and antinausea drugs, focusing on their mechanisms of action and specific medications like Metoclopramide and Ondansetron. This quiz covers indications, contraindications, and potential side effects of these medications. Perfect for students in pharmacology or nursing.