Antidepressants and Their Side Effects
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Questions and Answers

What are the common side effects associated with amitriptyline?

  • Sedation, sexual dysfunction, nausea, seizures (correct)
  • Cardiac, seizures, sexual dysfunction, sedation
  • Nausea, insomnia, hyperarousal, sensory disturbance
  • Nausea, sexual dysfunction, insomnia, instability

How long should antidepressants be taken for?

  • Only for as long as symptoms persist
  • At least 2 years for all patients
  • 6 – 9 months for all patients
  • Depends on the severity and recurrence of the episodes (correct)

What factors determine the risk of antidepressant discontinuation syndrome?

  • Frequency of dosing and initial dose
  • Patient's age and sex
  • Severity of the patient's depression
  • Type of drug and its duration of treatment (correct)

How is depression severity defined?

<p>By the impact on personal functioning and duration of the disorder (D)</p> Signup and view all the answers

What is the key message regarding the use of valproate in men and women?

<p>It should be avoided except in very exceptional circumstances (C)</p> Signup and view all the answers

What is recommended for pharmacy teams regarding valproate?

<p>They should discuss warnings and upcoming measures with their patients (C)</p> Signup and view all the answers

What should women of childbearing potential and girls do at their next annual specialist review regarding valproate?

<p>Review using a revised valproate Risk Acknowledgement Form (D)</p> Signup and view all the answers

What distinguishes bipolar depression from unipolar depression?

<p>Bipolar depression is generally more severe (B)</p> Signup and view all the answers

What potential side effect of lithium is Ms AC likely experiencing?

<p>Lithium toxicity (D)</p> Signup and view all the answers

Why should the prescription for sertraline be stopped for Ms AC?

<p>Sertraline can exacerbate manic symptoms (B)</p> Signup and view all the answers

What is the most appropriate mood stabilizer alternative for Ms AC?

<p>Lamotrigine (A)</p> Signup and view all the answers

What concern should be highlighted regarding the patient's current medicine list?

<p>The potential for drug interactions between sodium valproate and folic acid (B)</p> Signup and view all the answers

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