Antidepressants and Depression Quiz
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Questions and Answers

Which of the following is NOT a biological symptom of depression?

  • Loss of interest in activities (correct)
  • Sleep disturbances
  • Headaches
  • Unexplained chronic pain

Which neurotransmitters are postulated to be deficient in depression?

  • Noradrenaline and Histamine
  • GABA and Glutamate
  • Dopamine and Serotonin (correct)
  • Endorphins and Acetylcholine

What is the major cause of disability in the world?

  • Disturbance of thought
  • Emotional symptoms
  • Disturbance of cognition
  • Psychic depression (correct)

What is postulated to be the cause of depression?

<p>Deficiency of NA and/or 5-HT in the CNS (B)</p> Signup and view all the answers

What percentage of adults are estimated to suffer from depression globally?

<p>5% (A)</p> Signup and view all the answers

Which gender is more affected by depression?

<p>Women (C)</p> Signup and view all the answers

What is the main mechanism of action of tricyclic antidepressants (TCA)?

<p>Inhibition of neuronal reuptake of both 5-HT &amp; NA (B)</p> Signup and view all the answers

What is the suggested relation between improvement of emotional symptoms and neurotransmitter transmission in tricyclic antidepressants (TCA)?

<p>Enhancement of 5-HT transmission for emotional symptoms (D)</p> Signup and view all the answers

What is a common adverse effect of tricyclic antidepressants (TCA) related to blockade of muscarinic receptors?

<p>Blurred vision (A)</p> Signup and view all the answers

What condition has imipramine been used for in children older than 6 years of age?

<p>Nocturnal enuresis (C)</p> Signup and view all the answers

What is the main action of selective serotonin reuptake inhibitors (SSRI)?

<p>Block the reuptake of serotonin (A)</p> Signup and view all the answers

What is a common adverse effect related to selective serotonin reuptake inhibitors (SSRI)?

<p>Weight gain (B)</p> Signup and view all the answers

Which neurotransmitter's transmission enhancement is related to improvement of emotional symptoms in tricyclic antidepressants (TCA)?

<p>Serotonin (5-HT) (A)</p> Signup and view all the answers

What condition have tricyclic antidepressants (TCA) been used to treat, particularly amitriptyline?

<p>Migraine headache prevention (D)</p> Signup and view all the answers

What is the therapeutic use of tricyclic antidepressants (TCA) in treating chronic pain syndromes?

<p>Treating neuropathic pain (C)</p> Signup and view all the answers

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