Anticoagulant Medications Quiz
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Questions and Answers

Which of the following is a pharmacological effect of 2nd generation beta blockers?

  • Increase in heart rate
  • Delay of remodeling (correct)
  • Positive inotropy
  • Vasoconstriction of veins
  • How do mineralocorticoid receptor antagonists primarily affect the body?

  • Reduce angiotensin system activity (correct)
  • Reduce sympathetic tone
  • Increase parasympathetic tone
  • Increase angiotensin system activity
  • What is the primary purpose of SGLT2 inhibitors?

  • Increase blood glucose levels
  • Enhance heart performance (correct)
  • Increase sympathetic tone
  • Promote fibrotic activity
  • Which clinical condition is often treated with beta blockers?

    <p>Chronic heart failure</p> Signup and view all the answers

    What effect do 3rd generation beta blockers have on blood vessels?

    <p>Dilation of arteries</p> Signup and view all the answers

    In chronic heart failure, what happens to diastole length with beta blockers?

    <p>It lengthens</p> Signup and view all the answers

    What is the primary physiological effect of beta blockers on the heart?

    <p>Negative chronotropy</p> Signup and view all the answers

    What effect do Sodium-glucose cotransport protein 2 inhibitors have on heart load?

    <p>Reduce heart load</p> Signup and view all the answers

    What is the mechanism of action of Rivaroxaban?

    <p>Reversible inhibition of factor Xa</p> Signup and view all the answers

    Which specific anticoagulant neutralizer is used for Dabigatran?

    <p>Idarucizumab</p> Signup and view all the answers

    What is the clinical use of Warfarin?

    <p>Treatment of deep vein thrombosis</p> Signup and view all the answers

    Which drug is the antidote for Warfarin?

    <p>Vitamin K</p> Signup and view all the answers

    In case of life-threatening hemorrhage with Dabigatran, what specific neutralizer should be considered?

    <p>Idarucizumab</p> Signup and view all the answers

    What is the main effect of Rivaroxaban on factor Xa?

    <p>Irreversible inhibition</p> Signup and view all the answers

    What is the mechanism of action of Warfarin on coagulation factors?

    <p>Inhibition of synthesis</p> Signup and view all the answers

    Which drug should be considered if non-specific measures fail to control hemorrhagic complications from a factor Xa inhibitor?

    <p>Andexanet alfa</p> Signup and view all the answers

    What is the main reason for increased atrial and ventricular automaticity due to digoxin intoxication?

    <p>Enhanced calcium accumulation</p> Signup and view all the answers

    Which of the following symptoms is NOT typically associated with chronic digoxin intoxication?

    <p>Hypokalemia</p> Signup and view all the answers

    What treatment is recommended for acute digoxin overdose to manage hyperkalemia?

    <p>Sodium bicarbonate</p> Signup and view all the answers

    Which of the following drugs may increase serum digoxin levels by inhibiting its metabolism or cellular transport?

    <p>Antibiotics</p> Signup and view all the answers

    What is the main effect of digoxin on the ST segment in the electrocardiogram?

    <p>ST segment depression</p> Signup and view all the answers

    In patients with renal failure and digoxin toxicity, which treatment is preferred due to its ability to rapidly bind to digoxin and neutralize its effects?

    <p>Digoxin-specific antibodies</p> Signup and view all the answers

    Which diuretic medication has the primary mechanism of action of inhibiting carbonic anhydrase in the proximal renal tubules?

    <p>Acetazolamide</p> Signup and view all the answers

    What is a common side effect associated with the use of thiazide diuretics?

    <p>Hypokalemia</p> Signup and view all the answers

    Which diuretic medication is contraindicated for hypertensive patients due to its hyperhydration effect?

    <p>Acetazolamide</p> Signup and view all the answers

    Inhibition of which transporter in the ascending loop of Henle is the primary mechanism of action for Furosemide and Torasemide?

    <p>Na+/K+/2Cl- transporter</p> Signup and view all the answers

    Which diuretic medication promotes the excretion of Na, K, Cl, and Mg through urine and reduces uric acid excretion?

    <p>Furosemide</p> Signup and view all the answers

    What is a common side effect associated with the use of Acetazolamide?

    <p>Metabolic acidosis</p> Signup and view all the answers

    What is the main function of chronotropy in the heart?

    <p>Ability of cells to spontaneously generate an electrical impulse</p> Signup and view all the answers

    Which class of antiarrhythmic agents inhibits Na+ flux in cardiac myocytes phase 0 and K+ flow in phase 3?

    <p>Class Ia</p> Signup and view all the answers

    What is the mechanism of action of Lidocaine in treating arrhythmias?

    <p>Inhibits Na+ flux in phase 0 with fast dissociation kinetics</p> Signup and view all the answers

    What are the main side effects associated with the use of Class Ia antiarrhythmic agents?

    <p>Lupus erythematosus syndrome and CNS toxicity</p> Signup and view all the answers

    Which type of arrhythmias is Procainamide commonly used to treat?

    <p>Both supraventricular and ventricular arrhythmias</p> Signup and view all the answers

    What is the primary effect of Propafenone, Flecainide, and Ethacizine on cardiac myocytes?

    <p>Delay Na+ flow in CM phase 0 by expanding QRS complex</p> Signup and view all the answers

    In the heart, what does dromotropy refer to?

    <p>Ability to conduct the impulse from one cell to another</p> Signup and view all the answers

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