Anticoagulant Administration in PCI
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Questions and Answers

What is the common pathophysiology of unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI)?

  • Vulnerable plaque
  • Myocardial infarction with no obstructive coronary artery disease
  • Atherosclerotic plaque rupture with subsequent platelet-rich thrombus overlying the culprit lesion (correct)
  • Ischemia and no obstructive coronary artery disease

What differentiates unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI)?

  • The location of the thrombus overlying the culprit lesion
  • The degree of atherosclerotic plaque rupture
  • The presence or absence of elevated cardiac biomarkers (correct)
  • The extent of coronary artery disease

What is the abbreviation for myocardial infarction with no obstructive coronary artery disease?

  • MINOCA (correct)
  • INOCA
  • NSTE-ACS
  • NSTEMI

What is the abbreviation for ischaemia and no obstructive coronary artery disease?

<p>INOCA (C)</p> Signup and view all the answers

Which type of acute coronary syndrome is usually caused by an unstable atherosclerotic plaque rupture with subsequent platelet-rich thrombus overlying the culprit lesion?

<p>Non-ST segment elevation myocardial infarction (NSTEMI) (D)</p> Signup and view all the answers

What forms the group of acute coronary syndromes (ACS) usually caused by atherosclerotic disease?

<p>Unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI) (C)</p> Signup and view all the answers

Which of the following is NOT an advantage of LMWH over UFH?

<p>Higher risk of allergic reactions (A)</p> Signup and view all the answers

In the setting of NSTEACS, what is the documented benefit of thrombolytic therapy?

<p>There is no documented benefit (B)</p> Signup and view all the answers

Which condition is NOT considered a cause of increased myocardial metabolic demand?

<p>Coronary occlusion (A)</p> Signup and view all the answers

What characterizes a transmural myocardial infarction (MI)?

<p>Ischemic necrosis extending from the endocardium through the myocardium to the epicardium (A)</p> Signup and view all the answers

What is the leading cause of death in most industrialized nations throughout the world?

<p>Myocardial infarction (B)</p> Signup and view all the answers

What factor determines the severity of a myocardial infarction?

<p>The size of the affected muscle segment (A)</p> Signup and view all the answers

Which symptom is NOT commonly associated with a myocardial infarction?

<p>Headache and dizziness (B)</p> Signup and view all the answers

When are most cases of myocardial infarction clustered?

<p>Around midnight or early morning (C)</p> Signup and view all the answers

Which test is NOT required for the diagnosis of myocardial infarction?

<p>Urinalysis (A)</p> Signup and view all the answers

What is the normal range for Troponin I levels in blood?

<p>0.0- 0.4 ng/ml (D)</p> Signup and view all the answers

What should not delay the reperfusion strategy/treatment during diagnosis of myocardial infarction?

<p>Blood sampling for serum markers (A)</p> Signup and view all the answers

What is indicated if a patient experiences syncope or near-syncope without other cause, associated with a chest pain?

<p>Coronary angiography (C)</p> Signup and view all the answers

What is the best alternative for measuring injury to the heart muscle if troponin is not available?

<p>Creatine kinase muscle and brain subunits (CK-MB) (B)</p> Signup and view all the answers

What is the latest generation of cardiac enzyme testing that allows for detection of very low levels of troponin?

<p>High sensitivity troponin (hscTn) (D)</p> Signup and view all the answers

What is considered the best and preferred for measuring injury to the heart muscle due to its greater sensitivity and specificity?

<p>High sensitivity troponin (hscTn) (D)</p> Signup and view all the answers

Which of the following is recommended for all patients without contraindications at an initial oral loading dose of 150-300 mg?

<p>Aspirin (B)</p> Signup and view all the answers

Which antiplatelet agent is recommended in addition to aspirin and maintained over 12 months unless there are contraindications or an excessive risk of bleeding?

<p>Ticagrelor (C)</p> Signup and view all the answers

Which antiplatelet agent is recommended in patients proceeding to interventional treatment?

<p>Prasugrel (D)</p> Signup and view all the answers

When should a glycoprotein IIb/IIIa antagonist be considered?

<p>If there are complications at angioplasty (C)</p> Signup and view all the answers

What should be assessed at least twice 3-6 hours apart?

<p>Cardiac biomarkers (B)</p> Signup and view all the answers

What indicates ischemic dysfunction of a papillary muscle or mitral apparatus?

<p>Increased intensity of a preexisting murmur (B)</p> Signup and view all the answers

What does a rise of Tn occur within after injury and peaks within 1-2 days?

<p>2-3 hours (C)</p> Signup and view all the answers

What indicates overt pulmonary edema according to the Killip Classification?

<p>Cardiogenic shock (B)</p> Signup and view all the answers

Which leads should be used if the standard leads are inconclusive on the electrocardiogram?

<p>Right leads, posterior leads (C)</p> Signup and view all the answers

What is the primary purpose of echocardiography in the context of acute myocardial infarction?

<p>Detecting wall motion abnormalities (C)</p> Signup and view all the answers

Which arrhythmia occurs most commonly during the early hours after myocardial infarction?

<p>Sinus bradycardia (A)</p> Signup and view all the answers

What is the recommended treatment for premature ventricular complexes in the peri-infarct period?

<p>β-blockers (A)</p> Signup and view all the answers

Which arrhythmia is associated with a higher infarct mortality when occurring in the peri-infarct period?

<p>Atrial fibrillation (D)</p> Signup and view all the answers

What percentage of myocardial infarction patients experience ventricular fibrillation without antecedent-warning arrhythmias?

<p>50% (C)</p> Signup and view all the answers

What is the incidence of ventricular tachycardia in cases of myocardial infarction?

<p>20% to 40% (C)</p> Signup and view all the answers

Which arrhythmia occurs in approximately 10-20% of patients after myocardial infarction and is usually transient?

<p>Atrial fibrillation (D)</p> Signup and view all the answers

In what percentage of myocardial infarction cases does new bundle branch block occur?

<p>~15% (C)</p> Signup and view all the answers

What is the most common cause of sinus tachycardia in the peri-infarct period?

<p>Sympathetic stimulation (C)</p> Signup and view all the answers

What is the impact of Wenkebach rhythm in the peri-infarct period on long-term prognosis?

<p>It has no impact on long-term prognosis (B)</p> Signup and view all the answers

What is the primary reason for premature atrial contractions in patients with myocardial infarction?

<p>Atrial or sinus node ischemia (D)</p> Signup and view all the answers

What is the recommended treatment for sustained ventricular tachycardia during the peri-infarct period?

<p>Cardioversion (C)</p> Signup and view all the answers

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