Anticholinergics and Atropine
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Questions and Answers

A patient taking tolterodine tartrate reports experiencing a sudden decrease in urine output. What is the most appropriate nursing intervention?

  • Administer a diuretic medication to promote urine output.
  • Reassure the patient that decreased urine output is a common side effect and requires no intervention.
  • Increase the patient's oral fluid intake to stimulate urine production.
  • Notify the healthcare provider to evaluate for urinary retention. (correct)

A patient is prescribed an anticholinergic medication. Which instruction is most important to emphasize to the patient regarding environmental considerations?

  • Maintain a cool and consistent room temperature to minimize sweating.
  • Increase physical activity to promote better circulation.
  • Use a humidifier to prevent dry skin and maintain skin integrity.
  • Avoid prolonged exposure to hot environments. (correct)

Before administering atropine intravenously, which action is most crucial for the nurse to take?

  • Flush the IV line with saline before and after administration.
  • Administer undiluted directly into the IV line for rapid effect.
  • Mix the atropine with dextrose solution to prevent irritation.
  • Dilute the atropine in sterile water and administer slowly via IV push. (correct)

What finding indicates that benztropine has achieved its desired therapeutic effect?

<p>Reduction in involuntary movements (B)</p> Signup and view all the answers

A patient taking an anticholinergic medication is also a regular consumer of grapefruit juice. Which potential interaction should the nurse be aware of?

<p>Grapefruit juice may significantly elevate drug levels, increasing the risk of adverse effects. (B)</p> Signup and view all the answers

Which of the following physiological responses would be expected following the administration of an anticholinergic medication?

<p>Reduced gastrointestinal motility (D)</p> Signup and view all the answers

Atropine is prescribed to a patient before surgery. What is the primary reason for administering this anticholinergic medication in the preoperative setting?

<p>To reduce respiratory and gastrointestinal secretions (B)</p> Signup and view all the answers

A patient taking atropine reports experiencing blurred vision and dry mouth. Which of the following is the best explanation for these side effects?

<p>These are expected anticholinergic effects of the medication (D)</p> Signup and view all the answers

Which condition would be a contraindication for the administration of atropine?

<p>Glaucoma (A)</p> Signup and view all the answers

A patient with Parkinson's disease is prescribed benztropine. What is the primary mechanism of action of this medication in managing Parkinsonian symptoms?

<p>Blocking acetylcholine to the skeletal muscles and blocking dopamine reuptake (A)</p> Signup and view all the answers

A patient taking benztropine for Parkinson's disease is also prescribed an antihistamine for allergies. What potential drug interaction should the nurse be aware of?

<p>Increased risk of anticholinergic side effects (B)</p> Signup and view all the answers

Which of the following conditions would warrant caution when considering the use of benztropine?

<p>Psychosis (A)</p> Signup and view all the answers

Tolterodine tartrate is prescribed for a patient with an overactive bladder. How does this medication improve bladder control?

<p>By selectively blocking cholinergic receptors in the bladder (D)</p> Signup and view all the answers

Flashcards

Anticholinergics

Drugs that block the action of acetylcholine.

Anticholinergic Actions

Inhibits acetylcholine, increases heart rate, bronchodilation, decreases secretions and GI motility, dilates pupils.

Atropine - Action & Uses

Non-selective anticholinergic that inhibits acetylcholine by occupying receptors. Uses include dilating pupils and increasing heart rate when bradycardic.

Atropine - Side Effects

Dry mouth/skin, flushing, blurred vision, constipation, urinary retention, palpitations, hypertension.

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Atropine - Contraindications

Glaucoma, GI disorders that slow the GI tract, tachycardia, BPH, myasthenia gravis.

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Benztropine - Action

Blocks acetylcholine to skeletal muscles and dopamine reuptake.

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Benztropine - Uses

Decreases involuntary muscle movement, tremors, and muscle rigidity. Used for Parkinson's disease and pseudoparkinsonism.

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Tolterodine Tartrate - Action

Selectively blocks cholinergic receptors in the urinary bladder.

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Tolterodine Tartrate

Reduces urinary frequency, urgency, and incontinence by blocking acetylcholine effects on bladder.

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Anticholinergic Side Effects

Dry mouth, blurred vision, constipation, urinary retention, and tachycardia.

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Anticholinergic Interventions

Monitor vital signs (report tachycardia), I&O (urinary retention), bowel status (constipation).

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Anticholinergic Client Teaching

Avoid hot environments, increase fluid and fiber intake, report decreased urine output, use hard candy for dry mouth.

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Tolterodine Therapeutic Effect

Decreased bladder irritability, fewer trips to the bathroom; I & O remain balanced.

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Study Notes

  • Anticholinergic medications, also known as cholinergic antagonists or cholinergic blockers, work by opposing the effects of cholinergic agonists.
  • Anticholinergics inhibit acetylcholine action, leading to increased heart rate, bronchodilation, and decreased secretions.
  • Anticholinergics also decrease motility and peristalsis, reduce GI secretions, increase bladder sphincter constriction, and dilate pupils.
  • They can also reduce salivation, perspiration, tremors, and rigidity.

Atropine

  • Atropine is a non-selective anticholinergic medication
  • Atropine functions by inhibiting acetylcholine through occupying receptors, which increases heart rate by blocking vagal nerve stimulation.
  • Atropine Uses:
  • To reduce salivation, respiratory, and GI secretions before surgery.
  • To increase heart rate in cases of bradycardia.
  • To dilate pupils for eye exams.
  • Atropine Adverse Reactions:
  • Dry mouth and skin
  • Inability to sweat
  • Flushing, blurred vision
  • Constipation
  • Urinary retention
  • Palpitations
  • Hypertension
  • Atropine Contraindications:
  • Glaucoma
  • GI disorders that slow the GI tract
  • Tachycardia
  • Benign Prostatic Hypertrophy
  • Myasthenia Gravis
  • Atropine Interactions:
  • Antihistamines can increase anticholinergic effects.

Benztropine

  • Benztropine is an anticholinergic and antiparkinson medication that blocks acetylcholine to skeletal muscles.
  • It also blocks dopamine reuptake which allows domaine to work for a longer amount of time.
  • Benztropine Uses
  • Decreases involuntary muscle movement, tremors, and muscle rigidity
  • Treats Parkinson’s disease and pseudoparkinsonism.
  • Benztropine Adverse Reactions:
  • Reactions are very similar to atropine.
  • Benztropine Contraindications:
  • Glaucoma
  • Tardive dyskinesia
  • Myasthenia gravis
  • Caution with psychosis.
  • Benztropine Interactions:
  • It interacts with other anticholinergic drugs, as well as drugs that increase heart rate and blood pressure.

Tolterodine Tartrate

  • Tolterodine Tartrate is an anticholinergic medication
  • It selectively blocks cholinergic receptors in the bladder to treat overactive bladder.
  • Tolterodine then decreases urinary frequency, urgency, and incontinence.
  • Tolterodine Tartrate Adverse Reactions:
  • Reactions are similar to atropine.
  • Tolterodine Tartrate Contraindications:
  • Contraindications are similar to atropine
  • Tolterodine Tartrate Interactions:
  • Grapefruit juice can increase drug levels.

Anticholinergic Drugs: Nursing Considerations

  • Assessment:
  • Assess vital signs
  • Medication/medical history
  • What is the reason it's being given?
  • Urine output
  • Interventions:
  • Monitor vital signs and report tachycardia
  • Monitor I & O for urinary retention
  • Monitor bowel status for constipation
  • Provide mouth care
  • When administering atropine IV, dilute in sterile water and administer slowly at a rate of at least 1 mg/minute

Client Teaching

  • Avoid hot environments
  • Increase fluid intake and fiber
  • Report large decrease in urine output
  • Use hard candy for dry mouth
  • Practice good oral care
  • Wear sunglasses in bright light
  • Avoid driving if drowsiness occurs

Evaluation

  • Evaluation checks if the drug has had a therapeutic effect
  • Atropine effectiveness is based on the heart rate increasing if the client had bradycardia.
  • The effectiveness of benztropine is based on decreased involuntary movement.
  • Tolteradine Tartrate effectiveness is based on decreased bladder irritability, fewer trips to the bathroom, and balanced I & O.
  • For pre surgery patients, effectiveness will be based on the client reporting a decrease in dry mouth.

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Description

This lesson covers anticholinergic medications, also known as cholinergic antagonists or cholinergic blockers. It inhibits acetylcholine action, leading to increased heart rate, bronchodilation, and decreased secretions. It also highlights Atropine, its uses and adverse reactions.

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