Anticholinergic Drugs - Antihyperlipidemic & Vasodilators - PDF

Antihyperlipidemic & Vasodilators - Unit 6 Cholinergic Antagonistsor Anticholinergicsor Cholinergic blockers Unit 4 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergics Action of anticholinergics ? exactly opposite of cholinergic agonists Inhibits...

Antihyperlipidemic & Vasodilators - Unit 6 Cholinergic Antagonistsor Anticholinergicsor Cholinergic blockers Unit 4 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergics Action of anticholinergics ? exactly opposite of cholinergic agonists Inhibits the action of acetylcholine Increases heart rate Bronchodilation, decreases secretions Decrease motility and peristalsis, decrease GI secretions Increases bladder sphincter constriction Dilates pupils Decreases salivation and perspiration Decreases tremors and rigidity  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergics - Atropine Action Non-selective Inhibits acetylcholine by occupying receptors Increases heart rate by blocking vagal nerve stimulation Uses Decrease salivation and respiratory and GI secretions before surgery Increase heart rate when bradycardic Dilates pupils for eye exams  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergics - Atropine Side effects/Adverse reactions Dry mouth and skin Inability to sweat Flushing, blurred vision Constipation Urinary retention Palpitations Hypertension  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergics - Atropine Contraindications Glaucoma GI disorders that slow the GI tract Tachycardia Benign Prostatic Hypertrophy Myasthenia Gravis Interactions Can increase anticholinergic effects with antihistamines  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic ? Antiparkinson?s - Benztropine Action Blocks acetylcholine to the skeletal muscles Blocks dopamine reuptake to allow dopamine to work longer Uses Decrease involuntary muscle movement, tremors, and muscle rigidity Parkinson?s disease Pseudoparkinson?s  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic ? Antiparkinson?s - Benztropine Side effects/Adverse reactions Very similar to atropine  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic ? Antiparkinson?s - Benztropine Contraindications Glaucoma Tardive dyskinesia Myasthenia gravis Caution Psychosis Interactions Other anticholinergic drugs, other drugs that increase the heart rate, blood pressure  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic ? Tolterodine Tartrate Action Selectively blocks cholinergic receptors in the bladder Uses Overactive bladder ? decreases urinary frequency, urgency, and incontinence  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic ? Tolterodine Tartrate Side effects/Adverse reactions Similar to Atropine Contraindications Similar to atropine Interactions Grapefruit juice ? can increase drug levels  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic Drugs Assessment Vital signs Medication/medical history Know why it is being given Urine output  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic Drugs Interventions Monitor vital signs ? report tachycardia Monitor I & O (urinary retention) Monitor bowel status (constipation) Provide mouth care When giving atropine IV dilute in sterile water and give slowly IV push at least 1 mg/minute  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic Drugs Teach client to Avoid hot environments (unable to sweat and cool down) Increase fluid intake and fiber Report a large decrease in urine output Use hard candy to help with dry mouth Good oral care Wear sunglasses in bright light Not drive until the action is known as it can cause drowsiness  Antihyperlipidemic & Vasodilators - Unit 6 Anticholinergic Drugs Evaluation Importance to know why the nurse gave the medication and to know if the drug has a therapeutic effect. Atropine ? if client bradycardic ? heart rate increase *If before surgery ? client complains of a dry mouth Benztropine ? Decreased involuntary movement Tolteradine Tartrate ? Decreased bladder irritability ? fewer trips to the bathroom ? I & O remain balanced