Podcast
Questions and Answers
What type of bonds hold the heavy and light chains of an antibody together?
What type of bonds hold the heavy and light chains of an antibody together?
- Ionic bonds
- Disulphide bonds (correct)
- Hydrogen bonds
- Peptide bonds
How many constant regions are possible for the heavy chain in humans?
How many constant regions are possible for the heavy chain in humans?
- 4 (correct)
- 3
- 2
- 5
What is the result of somatic recombination in the heavy chain locus?
What is the result of somatic recombination in the heavy chain locus?
- Temporary change in the DNA
- No change in the DNA
- Permanent change in the DNA (correct)
- Removal of the V gene
What is the role of the hypervariable regions in the antibody-antigen interaction?
What is the role of the hypervariable regions in the antibody-antigen interaction?
What is the result of the combination of heavy and light chain variable regions?
What is the result of the combination of heavy and light chain variable regions?
What type of regions flank the gene segments that undergo VDJ recombination?
What type of regions flank the gene segments that undergo VDJ recombination?
What is the primary function of the RAG1 protein?
What is the primary function of the RAG1 protein?
What is the outcome of the cleavage reaction during VDJ recombination?
What is the outcome of the cleavage reaction during VDJ recombination?
What is the role of Ku proteins during VDJ recombination?
What is the role of Ku proteins during VDJ recombination?
What is the result of somatic hypermutation during an immune response?
What is the result of somatic hypermutation during an immune response?
In which location does somatic hypermutation occur?
In which location does somatic hypermutation occur?
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