Podcast
Questions and Answers
What is the purpose of somatic mutation in differentiated B-cells?
What is the purpose of somatic mutation in differentiated B-cells?
- To decrease antibody diversity
- To inhibit antibody production
- To increase the number of B cells
- To generate more diverse antibodies (correct)
Which gene regions are linked to the Class region in the Heavy chain of antibodies?
Which gene regions are linked to the Class region in the Heavy chain of antibodies?
- D and J regions
- Variable and Diversity regions
- Joining and Constant regions
- V and J regions (correct)
What process forms the variable region on the Heavy chain of antibodies?
What process forms the variable region on the Heavy chain of antibodies?
- Somatic Mutation
- Class Switching
- VDJ Recombination (correct)
- RNA splicing
What is the primary immunoglobulin formed after the DNA loop is created and transcribed?
What is the primary immunoglobulin formed after the DNA loop is created and transcribed?
Which sequence is removed by RNA splicing in the Light Chain of antibodies?
Which sequence is removed by RNA splicing in the Light Chain of antibodies?
When does class switching occur in B cells?
When does class switching occur in B cells?
What is the main immunoglobulin produced during secondary exposure to an antigen?
What is the main immunoglobulin produced during secondary exposure to an antigen?
What is the main purpose of Class Switching in antibody production?
What is the main purpose of Class Switching in antibody production?
What process leads to billions of different B cells with unique receptors for antigens?
What process leads to billions of different B cells with unique receptors for antigens?
Which process in antibody production is similar to VDJ recombination and involves switch regions?
Which process in antibody production is similar to VDJ recombination and involves switch regions?
Which cells express receptors for the Fc region of antibodies and participate in antibody-dependent cell-mediated cytotoxicity (ADCC)?
Which cells express receptors for the Fc region of antibodies and participate in antibody-dependent cell-mediated cytotoxicity (ADCC)?
During which exposure to an antigen do antibodies appear in the blood within hours, mostly in the form of IgG antibodies?
During which exposure to an antigen do antibodies appear in the blood within hours, mostly in the form of IgG antibodies?
What is recognized by phagocytes for opsonization?
What is recognized by phagocytes for opsonization?
Which sequences flank the V, D, J sequences in VDJ recombination?
Which sequences flank the V, D, J sequences in VDJ recombination?
What happens to unused J sequences in the VDJ recombination process?
What happens to unused J sequences in the VDJ recombination process?
What is the default constant region for B-cells in Ig production?
What is the default constant region for B-cells in Ig production?
Which cells differentiate into plasma cells after interacting with T helper cells?
Which cells differentiate into plasma cells after interacting with T helper cells?
Which process involves a loop of DNA formation that is lost during antibody production?
Which process involves a loop of DNA formation that is lost during antibody production?
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