10 Questions
What is the main function of the variable region in an antibody?
To give the antibody its specificity
What is the main difference between the different classes of antibodies?
The constant region structure and immune function
How many polypeptide chains are present in an antibody?
4
What is the term for the proteins that antibodies are a type of?
Immunoglobulins
What is the shape of an antibody molecule?
'Y' shaped
What is the function of the region at the tips of the 'Y' shaped antibody molecule?
Giving the antibody specificity
What is the basis for dividing antibodies into 5 major classes?
The constant region structure and immune function
What is the characteristic of the acid sequence in the tips of the 'Y' shaped antibody molecule?
It varies among different antibodies
What is the role of the constant region in an antibody?
Determining the mechanism used to destroy antigen
What is the number of acid residues in the region that gives the antibody specificity?
110-130
Study Notes
Antibody Structure
- Antibodies are proteins called immunoglobulins, consisting of four polypeptides: two heavy chains and two light chains, forming a "Y" shaped molecule.
Antibody Specificity
- The amino acid sequence at the tips of the "Y" shape (110-130 amino acids) varies among different antibodies, giving each antibody its specificity.
Antibody Function
- The constant region of an antibody determines the mechanism used to destroy antigens.
Antibody Classification
- Antibodies are divided into 5 major classes: IgM, IgG, IgA, IgD, and IgE, based on their constant region structure and immune function.
Antibody Structure
- Antibodies are proteins called immunoglobulins, consisting of four polypeptides: two heavy chains and two light chains, forming a "Y" shaped molecule.
Antibody Specificity
- The amino acid sequence at the tips of the "Y" shape (110-130 amino acids) varies among different antibodies, giving each antibody its specificity.
Antibody Function
- The constant region of an antibody determines the mechanism used to destroy antigens.
Antibody Classification
- Antibodies are divided into 5 major classes: IgM, IgG, IgA, IgD, and IgE, based on their constant region structure and immune function.
Learn about the structure and classification of antibodies, including their polypeptide chains, variable and constant regions, and the five major classes of antibodies.
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