Antibiotics for Ruptured Appendix
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Questions and Answers

What is the mechanism of action of aminoglycosides?

  • Inhibiting bacterial metabolism
  • Inhibiting cell wall synthesis
  • Inhibiting protein synthesis by blocking 30S ribosome (correct)
  • Inhibiting DNA replication

    • Why is tobramycin preferred over gentamicin for Pseudomonas infections?

  • Tobramycin is more effective against Pseudomonas (correct)
  • Tobramycin is less nephrotoxic
  • Tobramycin is more effective against Gram-positive bacteria
  • Tobramycin is less ototoxic

    • What is the primary concern when using aminoglycosides in elderly females?

  • Nephrotoxicity (correct)
  • Ototoxicity
  • Allergic reactions
  • Hypotension

    • What is the role of pharmacy in aminoglycoside dosing?

    <p>To assist in dosing calculations</p> Signup and view all the answers

    Which of the following is NOT a mechanism of resistance to aminoglycosides?

    <p>Increased efflux</p> Signup and view all the answers

    What is the usual dose of gentamicin in a patient with normal renal function?

    <p>6 mg/kg daily</p> Signup and view all the answers

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