Antibiotics and Their Mechanisms Quiz

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Questions and Answers

What is the primary action of antibiotics that inhibit protein synthesis?

  • They interfere with nucleic acid synthesis.
  • They bind to ribosomal subunits, halting protein production. (correct)
  • They prevent the assembly of ribosomes.
  • They disrupt cell wall formation.

Which class of antibiotics specifically targets the synthesis of folic acid in bacteria?

  • Macrolides
  • Aminoglycosides
  • Quinolones
  • Sulfonamides and trimethoprim (correct)

How do nucleic acid synthesis inhibitors affect bacteria?

  • They interfere with protein synthesis through ribosomal action.
  • They alter the structural integrity of the cell wall.
  • They inhibit folic acid production essential for metabolism.
  • They disrupt DNA and RNA synthesis, inhibiting replication. (correct)

Which of the following antibiotics is classified as a protein synthesis inhibitor?

<p>Tetracycline (D)</p> Signup and view all the answers

Which statement about sulfonamides and trimethoprim is true?

<p>They target distinct enzymes in the folic acid pathway. (A)</p> Signup and view all the answers

Which process is directly targeted by antibiotics such as Sulfonamides and Trimethoprim?

<p>Folic acid synthesis (B)</p> Signup and view all the answers

How do antibiotics typically affect bacterial cells without harming human cells?

<p>They target processes specific to bacteria that humans do not utilize. (C)</p> Signup and view all the answers

What is the result of antibiotics inhibiting the folic acid synthesis pathway in bacteria?

<p>Decreased bacterial metabolism and growth (A)</p> Signup and view all the answers

In the context of antibiotic action, what role do enzymes play in bacterial cells?

<p>They catalyze essential metabolic reactions. (D)</p> Signup and view all the answers

Why are antibiotics ineffective against human cells?

<p>Human cells have a different set of metabolic pathways. (B)</p> Signup and view all the answers

Flashcards

Antibiotic mechanism

How antibiotics stop bacterial growth by targeting essential bacterial metabolic pathways.

Folic acid pathway

A bacterial metabolic pathway essential for bacterial growth, targeted by particular antibiotics.

Sulfonamides

Antibiotics that inhibit folic acid synthesis in bacteria.

Trimethoprim

Antibiotics that also inhibit folic acid synthesis, often used in combination with sulfonamides.

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Bacterial growth inhibition

The effect of antibiotics that keep bacteria from multiplying.

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Bacterial metabolic pathways

Essential series of chemical reactions in bacteria that the antibiotics target to stop their growth.

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Antibiotic selectivity

Specificity of an antibiotic to affect bacterial metabolic pathways, not human cells.

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Protein Synthesis Inhibitors

Antibiotics that disrupt protein synthesis in bacteria by targeting their ribosome subunits (30S or 50S), leading to cellular dysfunction and death.

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Aminoglycosides

Example of antibiotics that inhibit protein synthesis by targeting bacterial ribosomes.

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Nucleic Acid Synthesis Inhibitors

Antibiotics that interfere with DNA and RNA synthesis, essential for bacterial replication, leading to bacterial death.

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Quinolones

Antibiotics that hinder DNA replication, a critical process for bacteria.

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Other Metabolic Inhibitors

Antibiotics that target bacterial processes other than protein or nucleic acid synthesis, which are crucial for bacterial survival.

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Folic Acid Pathway

Metabolic pathway crucial for bacteria, but not for humans. Antibiotics can disrupt this pathway.

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Sulfonamides

Antibiotics disrupting the folic acid pathway by targeting dihydropteroate synthase.

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Trimethoprim

Antibiotics that target dihydrofolate reductase, an enzyme in the folic acid pathway.

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