Anti-emetics and Anti-vertigo Drugs

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18 Questions

Which of the following antiemetic classes is associated with the antagonism of dopamine D2 receptors?

D2 Antagonists

Which antiemetic is a selective 5-HT3 antagonist and is used to treat chemotherapy-induced nausea and vomiting?

Ondansetron

Which antiemetic class is associated with the blockade of muscarinic receptors?

Muscarinic Antagonists

What is the mechanism of action of Metoclopramide as a prokinetic agent?

Blocks the normal inhibitory effect of dopamine on cholinergic smooth muscle stimulation

Which of the following antiemetics is a cannabinoid?

Dronabinol

What is the primary site of action of Metoclopramide as an antiemetic?

Chemoreceptor Trigger Zone (CTZ) of the medulla

Which of the following antiemetics does not cross the blood-brain barrier?

Domperidone

What is the primary mechanism of action of phenothiazines as antiemetics?

D2 antagonism and anti-muscarinic properties

Which of the following adverse effects is commonly associated with phenothiazines?

Extrapyramidal symptoms

Which of the following selective 5-HT3 antagonists has a longer half-life?

Palonosetron

What is the main advantage of using domperidone in patients taking levodopa?

It does not affect the efficacy of levodopa

Which of the following antiemetics is used to treat nausea and vomiting caused by chemotherapy?

Ondansetron

Which type of receptors are rich in the vestibular system, contributing to motion sickness?

Cholinergic M1 & Histamine H1

What is the primary mechanism of action of H1 antihistamines in treating motion sickness?

Inhibiting the influx of calcium to vestibular sensory cells

What is the primary pharmacokinetic characteristic of dronabinol?

Complete absorption with significant first-pass effect

Which of the following drugs is used to reduce anticipatory vomiting prior to cancer chemotherapy?

Diazepam

What is the primary advantage of meclizine over other H1 antihistamines in treating motion sickness?

It has a longer duration of action

What is the primary mechanism of action of cannabinoids in treating nausea and vomiting?

Acting as antiemetics and appetite stimulants

Test your knowledge of various medications used to treat nausea, vomiting, and dizziness. This quiz covers a range of anti-emetic and anti-vertigo drugs, including antihistamines, muscarinic antagonists, and more. Identify the different types of drugs and their uses.

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