15 Questions
What is the function of the anterior pituitary gland?
It secretes hormones that affect growth, sexual maturation, reproduction, metabolism, stress response, and fluid balance.
What is the most common type of pituitary adenoma?
Prolactinoma
What is acromegaly?
A rare condition characterized by an overproduction of GH
What are some clinical manifestations of acromegaly?
Thickening and enlargement of the bony and soft tissues on the face, feet, and head, proximal muscle weakness, joint pain, and sleep apnea
How is acromegaly diagnosed?
By evaluating plasma insulin-like growth factor-1 (IGF-1) levels and GH response to an oral glucose tolerance test (OGTT)
What hormones does the anterior pituitary gland secrete?
Growth hormone, prolactin, and tropic hormones
What is the most common type of pituitary adenoma?
Prolactinoma
What is acromegaly?
A rare condition characterized by an overproduction of GH
What are some clinical manifestations of acromegaly?
Thickening and enlargement of bony and soft tissues, joint pain, and voice deepening
How is acromegaly diagnosed?
Evaluating plasma insulin-like growth factor-1 (IGF-1) levels and GH response to an oral glucose tolerance test (OGTT)
What is the most common type of pituitary adenoma?
Prolactinoma
What is the most common age range for diagnosis of acromegaly?
40-45 years old
What is the main reason for the overproduction of GH in acromegaly?
GH-secreting pituitary adenoma
What are some clinical manifestations of acromegaly?
Increased joint pain
What diagnostic test is used to evaluate GH response in acromegaly?
Serum IGF-1 levels
Study Notes
Pituitary Gland and Acromegaly
- The anterior pituitary gland secretes several hormones, including growth hormone (GH), adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), prolactin, follicle-stimulating hormone (FSH), and luteinizing hormone (LH).
Acromegaly
- Acromegaly is a hormonal disorder caused by excessive production of growth hormone (GH) after normal growth has stopped, usually due to a benign tumor on the pituitary gland.
- The most common type of pituitary adenoma is a non-cancerous tumor that produces excessive GH, leading to acromegaly.
Clinical Manifestations of Acromegaly
- Clinical manifestations of acromegaly include joint pain and limited joint mobility, sleep apnea, excessive sweating, and enlarged hands and feet.
- Other symptoms may include coarse facial features, joint deformities, and changes in voice and skin texture.
Diagnosis of Acromegaly
- Acromegaly is diagnosed through a combination of physical examination, medical history, and laboratory tests, including GH level measurement and pituitary gland imaging.
- The oral glucose tolerance test (OGTT) is used to evaluate GH response in acromegaly.
Epidemiology of Acromegaly
- The most common age range for diagnosis of acromegaly is 40-50 years.
- The main reason for the overproduction of GH in acromegaly is a benign tumor on the pituitary gland.
Test your knowledge on the disorders of the anterior pituitary gland with this informative quiz. Learn about the various hormones secreted by this gland and how they affect growth, sexual maturation, and reproduction. From growth hormone deficiency to hyperprolactinemia, this quiz covers it all. Challenge yourself and enhance your understanding of endocrine system disorders.
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