Ankylosing Spondylitis and HLA-B27
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Questions and Answers

What percentage of Caucasians with ankylosing spondylitis are positive for LA-B27 alleles?

  • 50%
  • 7%
  • 95% (correct)
  • 100%

Study Notes

Ankylosing Spondylitis

  • A chronic inflammatory arthritis that affects the spine and sacroiliac joints
  • Strongly associated with the HLA-B27 allele in Caucasians:
    • 95% of ankylosing spondylitis patients are positive for HLA-B27 alleles
    • Compared to 7% of healthy individuals

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Description

This quiz covers the basics of Ankylosing Spondylitis, a chronic inflammatory arthritis that affects the spine and sacroiliac joints, and its strong association with the HLA-B27 allele.

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