Animal Studies in Drug Discovery
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Questions and Answers

Why is proper handling of rodents important in animal studies?

Improper handling can adversely affect experiments.

What is required for animal research protocols in laboratory settings?

Ethics committee approval

What are the two main routes of drug administration for laboratory animals?

Local and systemic (enteral or parenteral)

How does route of administration influence a drug's effect in laboratory animals?

<p>Anatomy, physiology, and biochemistry of route sites are different, impacting drug's effect.</p> Signup and view all the answers

What is one of the factors influencing how much volume can be administered into rodents?

<p>Maximum limit</p> Signup and view all the answers

How can dosage conversion be calculated for different species of animals?

<p>Using body surface area</p> Signup and view all the answers

What formula is used for converting doses based on body surface area?

<p>mg/m2 = km × mg/kg</p> Signup and view all the answers

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