Animal Health and Stress

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are some possible consequences of an animal being mismatched with its environment?

  • Increased stress, leading to a higher risk of disease (correct)
  • Improved overall health and well-being
  • No significant impact on the animal's health
  • Increased productivity and output

What are some examples of management practices that can be used to minimize animal stress and maximize stress resilience?

  • Providing adequate shelter and nutrition
  • Reducing overcrowding and providing enrichment
  • Implementing humane handling practices
  • All of the above (correct)

What are the two main stress axes involved in the physiological stress response?

  • Sympathetic-adrenal-medullary (SAM) axis and hypothalamic-pituitary-thyroid (HPT) axis
  • Parasympathetic-adrenal-medullary (PAM) axis and hypothalamic-pituitary-thyroid (HPT) axis
  • Parasympathetic-adrenal-medullary (PAM) axis and hypothalamic-pituitary-adrenal-cortex (HPA) axis
  • Sympathetic-adrenal-medullary (SAM) axis and hypothalamic-pituitary-adrenal-cortex (HPA) axis (correct)

How has the environment of laying hens changed over the past 100 years?

<p>From free-range to battery cage housing, and now to enriched aviary housing systems or free-range organic systems (D)</p> Signup and view all the answers

What are the key factors to consider when matching an animal to its environment?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of a good animal welfare assessment method?

<p>Subjective (C)</p> Signup and view all the answers

What is the importance of considering the physiology of the stress response in animal management?

<p>All of the above (D)</p> Signup and view all the answers

What is the main point emphasized in this content regarding animal welfare and management?

<p>All of the above (D)</p> Signup and view all the answers

What is the role of MHC molecules in the acquired immune response?

<p>MHC molecules present processed microbial antigens to T cells. (D)</p> Signup and view all the answers

What is the primary function of the neuroendocrine-immune system?

<p>To regulate the immune response and ensure its effectiveness without excessive activation. (D)</p> Signup and view all the answers

What are the primary effects of pro-inflammatory cytokines on the body?

<p>Fever response, sickness behavior, and protein catabolism. (C)</p> Signup and view all the answers

What is the primary function of hepatic acute-phase proteins (APP)?

<p>To support host defense and tissue repair processes. (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of the acquired immune response?

<p>Limited specificity and short-term protection. (A)</p> Signup and view all the answers

What is Systemic Inflammatory Response Syndrome (SIRS)?

<p>A severe, systemic response to infection with the potential for organ damage. (A)</p> Signup and view all the answers

Which of the following is a key characteristic of the innate immune response?

<p>Limited specificity and rapid response. (D)</p> Signup and view all the answers

What type of immunity is responsible for providing long-term protection against pathogens?

<p>Acquired immunity. (C)</p> Signup and view all the answers

Which of the following is NOT a step involved in the process of antigen recognition by the acquired immune response?

<p>Release of pro-inflammatory cytokines. (B)</p> Signup and view all the answers

What is the primary effect of DNA methylation on gene activity?

<p>Decreased transcription (C)</p> Signup and view all the answers

Which of the following is NOT a known mechanism of epigenetic modification?

<p>Acetylation of guanine nucleotides (C)</p> Signup and view all the answers

How do histone modifications influence gene activity?

<p>By affecting chromatin accessibility (A)</p> Signup and view all the answers

What is the relationship between the GR gene and stress response?

<p>The GR gene regulates the production of stress hormones (A)</p> Signup and view all the answers

How can epigenetics be targeted to improve livestock stress resilience?

<p>By manipulating epigenetic mechanisms (D)</p> Signup and view all the answers

What is the role of miRNA-18 and miRNA-124a in regulating GR levels?

<p>They inhibit the GR gene (B)</p> Signup and view all the answers

What is the significance of the zebra finch embryo's response to maternal song at higher temperatures?

<p>It suggests that epigenetic modifications can be influenced by environmental factors. (D)</p> Signup and view all the answers

Which of the following is a potential consequence of chronic stress?

<p>Impaired immune function (A)</p> Signup and view all the answers

What is the estimated heritability of the cortisol response 60 minutes after an ACTH challenge in porcine?

<p>0.68 (A)</p> Signup and view all the answers

What is the estimated heritability of cortisol levels at awakening in humans?

<p>0.28 (C)</p> Signup and view all the answers

Which of the following is NOT a modification that can occur on histone tails?

<p>glycosylation (B)</p> Signup and view all the answers

What is the role of microRNAs in regulating gene expression?

<p>They bind to and degrade target mRNA or repress its translation. (B)</p> Signup and view all the answers

Which of the following is an example of a pathogen-associated molecular pattern (PAMP)?

<p>Lipopolysaccharide (A)</p> Signup and view all the answers

How do modifications to histone tails affect gene expression?

<p>They affect the binding of transcription factors to DNA. (A)</p> Signup and view all the answers

What does the acronym 'H2' stand for in the context of this content?

<p>Heritability (B)</p> Signup and view all the answers

Which of the following is a stress hormone that can be used to measure individual resilience to stressors?

<p>Cortisol (D)</p> Signup and view all the answers

If you were looking for a fish species that will grow well in warm greenhouse water, which species might be most appropriate?

<p>Tilapia (C)</p> Signup and view all the answers

Which breed of cattle would be most appropriate for increasing milk production in Brazil?

<p>Holstein/Gir cross (B)</p> Signup and view all the answers

If you were faced with the challenge of increasing resistance of sheep to gastrointestinal parasites, which genetics could be introgressed into Canadian flocks?

<p>Gulf Coast (B)</p> Signup and view all the answers

Which of the following factors could contribute to an increased risk of viral infection?

<p>Disruption of circadian rhythms (D)</p> Signup and view all the answers

What is the significance of the statement that "viral infection worsens when circadian rhythm is abolished by disruption of a key circadian clock gene encoding the transcription factor BMAL1"?

<p>It highlights the importance of maintaining a regular sleep-wake cycle for health. (B)</p> Signup and view all the answers

Based on the information provided, what is the relationship between GHG emissions and the production of Q0 in Northern Europe?

<p>GHG emissions are expected to increase the production of Q0 in Northern Europe. (B)</p> Signup and view all the answers

How could genetic introgression be used to improve sheep resistance to gastrointestinal parasites?

<p>By introducing genes from parasite-resistant breeds into Canadian flocks. (C)</p> Signup and view all the answers

What is the main implication of seasonal variation in human BMAL1 levels?

<p>It suggests that humans are more susceptible to viral infections during winter months. (C)</p> Signup and view all the answers

Flashcards

Neuroendocrine-immune system

Integral system that communicates to regulate immune response effectively.

Pro-inflammatory cytokines

Signaling molecules like TNFα, IL-1, and IL-6 that activate the immune response.

Acute-phase response

Systemic reaction to infection that helps fight pathogens but may cause side effects.

Systemic Inflammatory Response Syndrome (SIRS)

Severe condition due to widespread inflammation, potentially leading to organ failure.

Signup and view all the flashcards

Sepsis

Life-threatening reaction to infection leading to organ dysfunction or failure.

Signup and view all the flashcards

Hepatic acute-phase proteins (APP)

Proteins produced by the liver in response to inflammation, aiding defense and repair.

Signup and view all the flashcards

Acquired immunity

Long-term immune protection against specific pathogens, with memory capabilities.

Signup and view all the flashcards

Immunological memory

The ability of the immune system to remember past infections for faster responses.

Signup and view all the flashcards

RCP6 and RCP8.5

RCP6 predicts lower greenhouse gas emissions while RCP8.5 predicts high emissions throughout the 21st century.

Signup and view all the flashcards

Dairy Production in Brazil

Increasing dairy production may require selecting appropriate cattle breeds for better yield.

Signup and view all the flashcards

Circadian Rhythms and Viral Infections

Circadian rhythms regulate virus progression, making infections worse when disrupted.

Signup and view all the flashcards

Genetic Resistance in Sheep

Introgressing resistant genetics can improve sheep’s ability to combat gastrointestinal parasites.

Signup and view all the flashcards

Alternative Breeds for Sheep Resistance

Identifying breeds like Merino or Rambouillet can enhance helminth resistance in Canadian flocks.

Signup and view all the flashcards

Fish Species in Aquaponics

Choosing the right fish is crucial for aquaponics, especially for temperature behavior.

Signup and view all the flashcards

Impact of BMAL1 on Infections

BMAL1 is a transcription factor affecting infection susceptibility based on seasonal variations.

Signup and view all the flashcards

Matching Livestock to Environment

Assessing if livestock and aquaculture species are suited to current farming practices helps optimize production.

Signup and view all the flashcards

Mycotoxins

Toxins produced by fungi that can affect health.

Signup and view all the flashcards

Corticosterone response

The measure of stress hormone levels in animals.

Signup and view all the flashcards

Histone proteins

Proteins that help package DNA into chromatin.

Signup and view all the flashcards

Chromatin modifications

Chemical changes to histone tails affecting gene accessibility.

Signup and view all the flashcards

Noncoding RNAs (ncRNA)

RNA that regulates gene expression without coding for proteins.

Signup and view all the flashcards

MicroRNA (miRNA)

A type of ncRNA that binds to mRNA and regulates translation.

Signup and view all the flashcards

Bacterial endotoxin

Components of bacterial cells, like lipopolysaccharides (LPS), that can trigger responses.

Signup and view all the flashcards

Epigenetics of stress

The study of how stress affects gene expression without altering DNA sequence.

Signup and view all the flashcards

Heritability estimates

Statistical measures of how traits can be passed down through generations.

Signup and view all the flashcards

DNA methylation

A process where a methyl group is added to cytosine nucleotides, impacting gene expression.

Signup and view all the flashcards

Histone modification

Changes to histone proteins that affect DNA accessibility and gene regulation.

Signup and view all the flashcards

Neuroendocrine-immune genes

Genes that link the nervous, endocrine, and immune systems and can be modified epigenetically.

Signup and view all the flashcards

GR gene and epigenetics

The Glucocorticoid Receptor gene is regulated by methylation and miRNAs in stress response.

Signup and view all the flashcards

miRNA role

MicroRNAs like miR-18 and miR-124a down-regulate GR levels by binding to its mRNA.

Signup and view all the flashcards

HPA axis

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates many body processes.

Signup and view all the flashcards

Polymorphisms in USP8

Genetic variations in the USP8 gene that affect ACTH production linked to stress responses.

Signup and view all the flashcards

Genetic and Epigenetic Matching

Matching animals with their environment based on genetic factors and epigenetic influences to reduce stress.

Signup and view all the flashcards

Impact of Housing Systems

The evolution from free-range to battery cage and enriched housing affects animal welfare and health.

Signup and view all the flashcards

Stress-Related Health Issues

Mismatches in environmental adaptation can lead to conditions like bone fractures and parasitic infections.

Signup and view all the flashcards

Matching Exotic Species

Assessing if exotic species like water buffalo and ostriches are suited for current farming systems.

Signup and view all the flashcards

Endangered Species Reintroduction

Ensuring that reintroduced species from zoos are compatible with wild ecosystems for survival.

Signup and view all the flashcards

Neuroendocrine Stress Response

The body's reaction to stress involving the brain and two major stress axes: SAM and HPA.

Signup and view all the flashcards

SAM and HPA Axes

Two pathways activated during stress: Sympathetic-Adrenal-Medullary and Hypothalamic-Pituitary-Adrenal.

Signup and view all the flashcards

Stress Management Practices

Techniques used to minimize animal stress and enhance resilience in production environments.

Signup and view all the flashcards

B cell receptors (BCR)

Membrane proteins on B cells that bind antigens.

Signup and view all the flashcards

Plasma cells

Terminally differentiated B cells that secrete antibodies.

Signup and view all the flashcards

T cell receptors (TCR)

Membrane proteins on T cells that recognize antigens presented by MHC.

Signup and view all the flashcards

Major histocompatibility complex (MHC)

Molecules that present processed antigens to T cells.

Signup and view all the flashcards

Humoral immunity

Immune response involving B cells and antibodies against extracellular pathogens.

Signup and view all the flashcards

Cell-mediated immunity (CMIR)

Immune response that involves T cells targeting intracellular pathogens.

Signup and view all the flashcards

Acquired immune response

A specific, delayed immune response that develops over days to weeks.

Signup and view all the flashcards

Memory B and T cells

Long-lived immune cells that facilitate rapid responses upon re-exposure to antigens.

Signup and view all the flashcards

Study Notes

Animal Health and Stress

  • Animal health is crucial for livestock and aquaculture producers, impacting production, product quality, and disease risk.
  • Consumers demand high-quality, ethically produced animal products at reasonable prices.
  • Many livestock pathogens are zoonotic, meaning they can be transmitted to humans, making animal health crucial for human health.

Antimicrobial Resistance (AMR)

  • Antibiotics and other antimicrobials have been heavily used in livestock and aquaculture, contributing to AMR.
  • AMR pathogens are a significant concern and new strategies to maintain animal health are needed.

Animal Stress Response

  • Domesticated animals experience various stressors (psychological, physical, chemical, biological).
  • Stress is defined as something that disrupts homeostasis and elicits a response.
  • The stress response is a conserved evolutionary response to perceived danger. It activates various physiological systems, including cardiovascular, metabolic, musculoskeletal, neuroendocrine, and immune systems. The response can manifest as "fight", "flight" or "freeze".
  • Excessive or chronic stress can lead to psychological, metabolic, reproductive, and immunological disorders, as well as increased susceptibility to infections and autoimmune diseases, and cancer.

Animal Resilience to Stress

  • Resilient animals can withstand, adapt to, and recover from stress, maintaining homeostasis.
  • Genetics, environment, and epigenetic mechanisms influence stress resilience.
  • Animals with lower stress resilience may be more susceptible to disease from exposure to stressors.

Examples of Stressors

  • Physical stressors: heat, cold, transport, noise, electrical restraint
  • Chemical stressors: mycotoxins, bacterial toxins, pro-inflammatory cytokines, neuropeptides
  • Biological stressors: microbes, pathogens, parasites, viral infections
  • Psychological stressors: isolation, re-grouping, noises

Biomarkers of Stress

  • Biomarkers are biological indicators of stress, useful for monitoring animal health.
  • Examples include catecholamines, glucocorticoids, ACTH, cytokine levels, various antibodies, and temperature.

Immune System in Response to Stress

  • The innate and adaptive immune systems play a vital role in restoring homeostasis.
  • Effective immune function is crucial for protecting against pathogens.
  • Microbial stressors may affect immune response.

Stress, Disease, and Epigenetics

  • Genetic and epigenetic variations contribute to the variability in animal response to stress, and their resilience to disease.
  • Stress factors can be influenced by the environment and the animal's genetic predisposition.
  • Maternal factors and early life experiences can have long-term effects on immune and physiological development.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Animal Health and Welfare Quiz
15 questions
Animal Health and Dermatology Quiz
51 questions
Essential Minerals for Animal Health
10 questions
Use Quizgecko on...
Browser
Browser